I see you don’t understand how an adenovirus vector vaccine works. It is intended to go into the nucleus.
From Google answering “does the adenovirus enter the nucleus?”
Answer:
Adenovirus targets its genome to the cell nucleus by a multistep process involving endocytosis, membrane penetration and cytoplasmic transport, and finally imports its DNA into the nucleus.
The ADENOVIRUS itself should NOT enter the nucleus. It’s genome should. The virus itself should only get as far as the cellular fluid, and then, through a series of steps, it’s GENOME enters the nucleus.
Is that what you’re saying? Because those aren’t the words you used.