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Another satisfied customer :(

Posted on 08/09/2021 2:52:13 PM PDT by uscga77

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To: Steve Van Doorn

This led me to reading about chalconoids and their effect on SARS‑CoV‑2.

That reading is proving to be a fascinating continuation of longstanding interest in the remarkable power of bioflavonoids.


61 posted on 08/10/2021 3:07:57 PM PDT by Arcadian Empire
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To: uscga77

Prayers for mother and child.


62 posted on 08/10/2021 3:18:43 PM PDT by KYGrandma
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To: Steve Van Doorn

Steve: “said, “P. Yoelli is the bridge for malaria between mice and humans”
via mosquito
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0167178

Me: Where, oh where, is there any proof P.Yoelli is a “bridge for malaria between mice and humans” in this paper about animal models for studying malaria transmission by South American mosquitoes? It is not there.

Can you cite one case of a human syffering from P. Yoelli? No, you can’t, any more than you can back up your claim that P. Yoelli causes Vivax malaria, which is totally absurd, as by definition, P. vivax causes it.

Steve: “said, “While P. vivax can go cerebral, it is fairly rare (where you live)”
https://pubmed.ncbi.nlm.nih.gov/31533821/

Me: You added the “where you live” part. Actually, it’s nonexistent where I live now (USA). The link you provided says vivax is recognized as “a major cause of severe and cerebral malaria” in areas where vivax predominates. Note *severe* and cerebral (severe does not always mean cerebral). This is only to be expected. For example, if 80% percent of cases are vivax, and 5% are severe, then it would be “a major cause” even if 15% are falciparum and 20% of those are severe.

The fact remains that falciparum is much more likely to go cerebral than vivax. Look it up. You will find it stated over and over and over.

I still don’t get why you think P. Yoelli causes vivax. Can you please explain?
Steve: “You said in the next line you said, “Malaria parasites (genes) are also nowhere”

Me: You added the genes part. I would not be be surprised if the virus shared one or more genes with plasmodium species (or lettuce or house cats or even possums). All living things share many genes (and viruses, too, even though they are not considered living things really). But to cause cerebral malaria, as you claim, you need the actual parasites.

Steve: “I’m going to stop here. First we have to work out the vectors of malaria and the genes that are in covid. Before we move on to these next issues.
You seem to be stuck on the first points. Without understanding the premise you can’t continue.”

Me: We know the vector for malaria. It’s mozzies. Covid is not a vector-borne disease. It is spread from human to human via respiratory droplets.

Now for your Perez “report”. Have a look at this:

- - -
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033698/#!po=22.7273

“Sequences that completely match the insertion 3 and 4 sequences were not found in any HIV-1 sequences. This clearly shows that these insertion sequences are widely present in living organisms including viruses, but not HIV-1 specific. All these regions in HIV-1 envelope glycoprotein are highly variable with many large insertions and deletions, indicating that they are not essential for biological functions of HIV-1 envelope glycoprotein.

(snip)

Second, these insertions are present not only in 2019-nCoV viruses but also in three betaCoV sequences from bats: two (ZC45 and ZXC21) from Zhejiang deposited in GenBank in 2018 and RaTG13 from Yunnan obtained in 2013 [8]. The RaTG13 is much more similar to 2019-nCoV than both ZC45 and ZXC21 (Figure 1A). The similarity of the spike protein between RaTG13 and 2019-nCoV is 97.7%.”
- - -

Personally, I suspect SARS-COV-2 came from the Wuhan lab. It may or may not have been a product of the gain-of-function research being carried out there. I would not be surprised if it is. That said, you do need to understand that just because SARS-COV-2 might have some genes in common with other viruses (like HIV) or even protazoa (like malaria parasites) — and even insects and mammals — that does not mean it can cause AIDS or malaria in humans (or cause them to grow tails or whatever). See here:

https://science.howstuffworks.com/life/genetic/people-bananas-share-dna.htm

Just because humans have a whole bunch of genes in common with banana trees does not mean we can sprout banana stalks out of our heads.

Finally, if the SARS-COV-2 virus really does happen to have a gene in common with P. Yoelli, that hardly means it can magically produce P. vivax parasites!

You apparently have the bizarre notion that SARS-COV-2 can cause cerebral malaria, and therefore Decadron should not be used to treat Covid patients. Do you actually believe SARS-COV-2 can somehow release malaria parasites into the blood of Covid patients? Seriously? And if this miraculous thing can actually happen, why has no one noticed them in the blood drawn from Covid patients?

You have accused doctors of killing patients (including one of our fellow Freepers) by giving them Decadron because it is contraindicated in malaria. I’m sorry, but this is nuts.


63 posted on 08/10/2021 6:33:15 PM PDT by CatHerd (Not a newbie - lost my password)
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To: CatHerd
said, "Where, oh where, is there any proof P.Yoelli is a “bridge for malaria between mice and humans”"

Maybe you're getting hug up on the terms I use? I'm not sure.

The last report I gave the term they used "anophelines" (which means. a carry the malaria parasite and transmit the disease to humans)

Dr Perez referenced a source.
It's even on Wikipedia.
here is another
Validation of Plasmodium vivax centromere and promoter activities using Plasmodium yoelii
https://pubmed.ncbi.nlm.nih.gov/31860644/

asked, "human syffering from P. Yoelli"

They suffer from the symptoms that Plasmodium vivax give.

said, "severe does not always mean cerebral"
ok... that is fine. Though cerebral the key part of 'brain fog' which I believe is the cause of the problem with covid. Which we can go back to that later once you understand the vectors of malaria.

said, "falciparum is much more likely to go cerebral than vivax"
Either way it makes no difference the question is the vectors of malaria. Which you seem to now agree that vivax can lead to cerebral. Good.

"Covid is not a vector-borne disease" Which you're saying here is that covid doesn't have P.Yoelli that forms the three spikes. Contrary to Perez report.

Can you explain why you have this belief?

said, look at the report from Chuan Xiao

Chuan Xiao never mentioned plasmodium Yoelii or STAT1 which was both are proof of a human made virus.

64 posted on 08/10/2021 8:43:41 PM PDT by Steve Van Doorn (*in my best Eric Cartman voice* 'I love you, guys')
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To: Arcadian Empire
said, "This led me to reading about chalconoids and their effect on SARS‑CoV‑2."

I remember reading something about that a while ago. I must have had covid or infected with someone's vax .. I'm fogged. Can you reference something you read on chalconoids? Thanks
65 posted on 08/10/2021 11:37:29 PM PDT by Steve Van Doorn (*in my best Eric Cartman voice* 'I love you, guys')
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To: mad_as_he$$

... started HCQ and had their asthma diminish significantly or go away all together.
_______________________________

Have heard similar anecdote wrt: Ivermectin.


66 posted on 08/11/2021 5:02:40 AM PDT by reformedliberal (Make yourself less available.)
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To: reformedliberal

Interesting. Thanks!


67 posted on 08/11/2021 5:19:28 AM PDT by mad_as_he$$
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To: Steve Van Doorn

Steve: “said, “Where, oh where, is there any proof P.Yoelli is a “bridge for malaria between mice and humans””

Maybe you’re getting hug up on the terms I use? I’m not sure.

The last report I gave the term they used “anophelines” (which means. a carry the malaria parasite and transmit the disease to humans)”

Me: Anopholine refers to a genus of mosquito (Anopholes). Some species of this genus are malaria vectors. Some transmit P. yoelli to rats and mice. Humans do not contract P. yoelli. It’s mousie ratty thing.

Steve: “Dr Perez referenced a source.
It’s even on Wikipedia.
here is another
Validation of Plasmodium vivax centromere and promoter activities using Plasmodium yoelii
https://pubmed.ncbi.nlm.nih.gov/31860644/

Me: I don’t know what you think this proves. Researchers have been studying malaria in the lab using rats and mice for a very long time. The difficulty is they are stuck studying the murine strains and mucking about with gene manipulation. This hardly proves that P. yoelli could infest humans or produce vivax malaria in a human. You will find many, many mouse studies using transgenic P. Yoelii in an effort to produce a vaccine for P. falciparum. Like this one:https://malariajournal.biomedcentral.com/articles/10.1186/s12936-016-1248-z

Steve: “asked, “human syffering from P. Yoelli”

They suffer from the symptoms that Plasmodium vivax give.”

Me: What on earth do you mean? Yes, Covid patients and patients who have contacted vivax may present with similar symptoms: fever, headache, fatigue, etc. So do those with the ‘flu. Similar symptoms do not equal Covid somehow miraculously causing malaria. You need actual malaria parasites for that.

Steve: “said, “severe does not always mean cerebral”
ok... that is fine. Though cerebral the key part of ‘brain fog’ which I believe is the cause of the problem with covid. Which we can go back to that later once you understand the vectors of malaria.”

Me: I understand the vectors of malaria just fine: certain species of the Anopholes mosquito.

Do you understand the symptoms of cerebral malaria? Seizures, delirium, coma, and other deathly fun stuff. Hardly brain fog.

In case you think brain fog means seizures, delirium, coma, etc., here you go:

https://www.healthline.com/health/covid-brain-fog

- - -
Manifestations of severe malaria:

The manifestations of severe malaria differ depending on the age of the patient and previous exposure.1 In the first 2 years of life severe anaemia is a common presenting feature of severe malaria. In older children seizures and cerebral malaria predominate; whereas in adults acute renal failure, acute pulmonary oedema, liver dysfunction, and cerebral malaria may all occur. Metabolic acidosis, mainly a lactic acidosis, is common at all ages. Severe malaria is a multisystem disease, and the outcome often depends on the degree of vital organ dysfunction.

Link: https://jnnp.bmj.com/content/69/4/433
- - -

Steve: “said, “falciparum is much more likely to go cerebral than vivax”
Either way it makes no difference the question is the vectors of malaria. Which you seem to now agree that vivax can lead to cerebral. Good.”

Me: It is quite rare, but it can happen:

https://pubmed.ncbi.nlm.nih.gov/19742268/

Why is the question vectors? Everyone knows mozzies are the vector for malaria.

Steve: “”Covid is not a vector-borne disease” Which you’re saying here is that covid doesn’t have P.Yoelli that forms the three spikes. Contrary to Perez report.”

Me: No, what I am saying is Covid is not a vector-borne disease. No mosquitoes, fleas, ticks or lice required. It is transmitted directly from human to human via respiratory droplets.

Do you not know what a disease vector is? Look it up!

Examples of vector-borne diseases are dengue fever (mosquitoes are the vector), Lyme disease (ticks are the vector), bubonic plague (fleas are the vector), Chagas disease (triatomine bugs are the vector), typhus (lice), leishmaniasis (sand flies) — well, you get the picture.

As for your assertion that P. Yoelli “form the three spikes” (I presume spikes on the SARS-COV-2 virus — I thought it had more than three lousy spikes) — if you mean a tual malaria parasites, how ridiculous can you get? Surely you cannot mean that.

If you mean the fragment of genetic material from P. Yoelii that Perez proposes was inserted in the lab, if you scroll down to Table 12 in the paper you posted here, you will see that as SARS-CoV-2 mutates, it preferentially deletes the P. Yoelii fragment. He cites this preferential jettisoning of the P. Yoelii fragment as proof that it was artificially inserted in the lab. If he is correct, and that trend has continued to play out, most SARS-CoV-2 now in existence has no P. Yoelii genetic material at all. None! Here is the link, so you can check for yourself:

https://www.researchgate.net/publication/342926066_COVID-19_SARS_and_Bats_Coronaviruses_Genomes_Peculiar_Homologous_RNA_Sequences_Jean_Claude_perez_Luc_Montagnier

Perez makes a pretty good argument that SARS-CoV-2 was created in a lab. Here is another paper that supports that view and is more easily understood by we laymen:

https://thebulletin.org/2021/05/the-origin-of-covid-did-people-or-nature-open-pandoras-box-at-wuhan/

Surely now you can see that SARS-CoV-2 does not somehow magically produce vivax malaria in Covid patients? And therefore doctors are not killing their patients with Decadron, but rather saving lives?


68 posted on 08/11/2021 11:08:36 AM PDT by CatHerd (Not a newbie - lost my password)
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To: CatHerd
Anopheles is a Greek term. For medical reasons to mean a carrier of diseases that contract to humans. That was used for a genus of mosquito.

said, "Humans do not contract P. yoelli"

We don't contract slugs either. Though we can contract the diseases the slug carries. I'm not sure why this is so difficult.

The rest of your post seems to be over similar miss understandings of basic communication.
I have to ask myself why?

example: "SARS-CoV-2 does not somehow magically produce vivax malaria in Covid patients"
I never said it does.
69 posted on 08/11/2021 1:35:03 PM PDT by Steve Van Doorn (*in my best Eric Cartman voice* 'I love you, guys')
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To: CatHerd
yes the P. Yoelli spike does drop off after the S1 spike mutates. There are hundreds of mutations it forms into. Some of which are new munitions of covid. One is particularly concerning me.

said, "therefore doctors are not killing their patients with Decadron, but rather saving lives?"

Those doctors that prescribe Decadron are being miss lead in a very deadly way. I can't seem to explain why to you. Try to understand P. Yoelli is a carrier not the disease. Parasites can only carry specific types of diseases.

We don't seem to have a good line of communication. I'm sorry.
70 posted on 08/11/2021 2:13:49 PM PDT by Steve Van Doorn (*in my best Eric Cartman voice* 'I love you, guys')
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To: Steve Van Doorn

Yes, certain species of anopheles mosquito can carry diseases to humans, like P. falciparum, P. vivax, P. ovale, and P. malariae. Certain species can carry P. knowlesi to monkeys and humans. Certain species can carry P. berghei, P.chabaudi, P. vinckei and P. yoelii to rats and mice.

People do not contract the murine varieties (such as P. yoelii and rats and mice do not contract the forms that infest humans (like P. vivax).

Don’t you get it? The disease IS P. yoelii. The carrier (vector) is the mosquito!

Not only can P. yoelii not be contracted by humans, it cannot carry P.vivax or any other disease. ****It is the disease!*** And it is only contracted by rats and mice.

Furthermore, the teensy-weensy little SARS-CoV-2 virus cannot “carry” malaria parasites (which are humongous in comparison). Only mosquitoes can. What is so hard to understand about that?

The reason you cannot explain it is because you have zero understanding of how any of this works.


71 posted on 08/11/2021 6:21:08 PM PDT by CatHerd (Not a newbie - lost my password)
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To: Steve Van Doorn

Steve: “Those doctors that prescribe Decadron are being miss lead in a very deadly way. I can’t seem to explain why to you. Try to understand P. Yoelli is a carrier not the disease. Parasites can only carry specific types of diseases.”

Me: No, you need to understand that P. Yoelii is the parasite that causes the disease. The mosquito is the vector (carrier). And, again, it only is only contracted by rats and mice.

You do not even understand why Decadron is contraindicated in cerebral malaria, do you? Nor do you understand how malaria parasites can cause cerebral malaria and why there must be actual parasites (not some tiny scrap of genetic material for an innocuous protien) to cause cerebral malaria.

Maybe you need to study up a bit more.

Why Dacadron can be life saving at later stages of Covid in an easy to understand article:

https://www.news-medical.net/news/20210629/How-does-dexamethasone-therapy-in-COVID-19.aspx

I am sorry there appears to be poor communication as well. I’m sorry I have to say your theory that Covid patients have cerebral malaria is utterly nonsensical and unscientific. I don’t mind if you keep your harebrained theories on your Q threads. Go to town with it. But when you post on threads about fellow freepers who have died of Covid and where people are worried about loved ones, and give out erroneous medical advice and accuse doctors of killing people I will challenge you. I am so sick of FR being taken over with this nonsense.


72 posted on 08/11/2021 7:27:16 PM PDT by CatHerd (Not a newbie - lost my password)
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To: CatHerd
I'm going to try one last time with you. I honestly think you're a bad actor on FR at this point. you argue without making any sense. You sound like a liberal fact checker twisting what people say in order to make an argument that was never stated.

example: you CLAIM I said,
"Covid patients have cerebral malaria is utterly nonsensical and unscientific"

I agree it is so stop saying it. I didn't. YOU did.

said "it only is only contracted by rats and mice"
Either way. P. Yoelii is the parasite genes which are the three spikes on covid. P. Yoelii is usually attributed the P. vivax malaria infections. Does this statement register in your head as saying covid is malaria?

How would you word it to make it clear it doesn't? you can't can you? The reason is your don't read the sentence you interpret the sentence.

After re-reading this I took a shot in the dark. found this.
Plasmodium yoelii. Both Py17XNL and Py17XL infections induced a maximum activation of STAT1"
They enhanced STAT1 with Plasmodium yoelii? I have to look in to this some more.
https://pubmed.ncbi.nlm.nih.gov/18954557/

said, "You do not even understand why Decadron is contraindicated in cerebral malaria, do you?"
IL-10 and TGF-β are negatively effected. They regulates cytokines. This can cause an infection. Which will attack the kiddies. can cause swelling and blood clots (low platelets.)
73 posted on 08/11/2021 9:34:04 PM PDT by Steve Van Doorn (*in my best Eric Cartman voice* 'I love you, guys')
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To: Steve Van Doorn

Steve: “I’m going to try one last time with you. I honestly think you’re a bad actor on FR at this point. you argue without making any sense. You sound like a liberal fact checker twisting what people say in order to make an argument that was never stated.”
-
Me: You are the one making no sense because you have no understanding of what you are carrying on about. Typical Q follower response to make unfounded accusations and ad hominem attacks when you can’t support your own argument. Really, accusing me of being a “bad actor”. Sad. I thought better of you than that.

I have never knowingly twisted your words. I have had serious trouble trying to make sense of the sentences you write. I have done my best to figure out what you mean in good faith.
-
Steve: “example: you CLAIM I said,
“Covid patients have cerebral malaria is utterly nonsensical and unscientific”

I agree it is so stop saying it. I didn’t. YOU did.”
-
Me: No, I would never say such a thing.

Quote from your post (link follows below):
-
Steve: “Doctors are giving drugs that are killing them. This case was with Freeper terart. I believe the steroid Decadron (Corticosteroids) killed her.

The spikes of covid are the parasite that creates malaria. on the directions for “Corticosteroids should not be used in cerebral malaria.””
-
Me: You indicate here that you believe the spikes on the SARS-CoV-2 virus are actually malaria parasites (which I have proven is a laughable claim). You further assert that doctors are killing Covid patients because corticosteroids should not be used in cerebral malaria. Therefore, it appeared to me that you believe that Covid causes cerebral malaria. And, no, I have not misquoted you.

Link to your post quoted above:
https://freerepublic.com/focus/chat/3983555/posts?page=22#22
-
In your next post, answering mine, you say:
-
Steve: “said, “Do you actually believe the SARS-CoV-2 protein spikes are malaria parasites???? Seriously?”

Yes. The genes from Plasmodium Yoelii the parasite that causes malaria.”
-
Me: So your “yes” means you do believe that? Or is it that you assume the “genes” somehow cause cerebral malaria in Covid patients?

Continuing on with this post, you say:
-
Steve: “Plasmodium Yoelii parasite gene that forms the spikes of covid-19 (attributing the P. vivax malaria infections) P. vivax malaria (lessor form of malaria) often contributes to cerebral malaria” and “This is why ivermectin works. It’s what causes the loss of brain grey matter (brain fog) after people get infected with covid.
It’s why some medicines doctors are giving is killing people.”
-
Casting aside the ridiculous notion that P. yoelii causes P. vivax infestation (addressed later in point 2), now you claim ivermectin “works” in the treatment of cerebral malaria and seem to think this is some sort of proof Covid patients actually have cerebral malaria. Again, ivermectin does not! Ivermectin is never used to treat malaria, cerebral or otherwise. It is not an antimalarial drug. Because it has insecticidal properties, may help prevent malaria in areas where it is widely used by shortening the lifespan of the vector (mosquito). But I repeat myself.

Link to post quoted above: https://freerepublic.com/focus/chat/3983555/posts?page=45#45
-
In a later post, you say:
-
Steve: “They suffer from the symptoms that Plasmodium vivax give.”
Link:https://freerepublic.com/focus/chat/3983555/posts?page=64#64
-
Okay, you think this, and appear to be the only person in the world who thinks this. But we have already been round about this. Headache is a symptom of Covid and it is a also a symptom of malaria, eating ice cream too fast, a brain tumor, the ‘flu, I could go on and on. Appropriate treatment would differ, depending on the causative agent. Same with all the other symptoms. The fact remains that the causative agent (or to be more precise, the etiological driver) of Covid symptoms is SARS-CoV-2, not malaria, not ice cream, not a brain tumor.
-
To continue on with your last post now:
-
Steve: “said “it only is only contracted by rats and mice”
Either way. P. Yoelii is the parasite genes which are the three spikes on covid. P. Yoelii is usually attributed the P. vivax malaria infections. Does this statement register in your head as saying covid is malaria?

How would you word it to make it clear it doesn’t? you can’t can you? The reason is your don’t read the sentence you interpret the sentence.”
-
Me: I have no choice but to attempt to interpret, because your assertions are nonsensical and your arguments disjointed. In these few sentences, you have piled up quite the stack of erroneous assumptions, so let’s take them one by one.

1. Firstly, why do you keep talking about “the three spikes on Covid”? Here is what the virus looks like, spikes and all:

https://www.sdcity.edu/about/communications/imgs/covid-19.jpg

Do you see only three spikes?

Or do you think the codons discussed in Perez’s paper are spikes? Is that where your confususion lies?

What is a codon?
https://www.genome.gov/genetics-glossary/Codon

This may help you understand better:
https://www.nature.com/scitable/topicpage/nucleic-acids-to-amino-acids-dna-specifies-935/

If you are going to insist SARS-CoV-2 has three spikes, please back up your claim. If you have not mistakenly thought codons are spikes, then I would love to know where you got the idea it has three spikes.

I tried to be kind to you earlier by providing a link that explains how the insertion of genetic fragments at a crucial site would increase the infectivity of the SARS-CoV-2 virus in a way that may be easier for you to understand (and yes, you’ll read more about those codon thingies):

https://thebulletin.org/2021/05/the-origin-of-covid-did-people-or-nature-open-pandoras-box-at-wuhan/

Perhaps you should try reading it.
-
2. Steve: “P. Yoelii is usually attributed the P. vivax malaria infections.”
-
Me: ***I triple dog dare you to find a single citation of this.*** I am confident you cannot. It is utterly absurd. P. yoelii cannot cause vivax infections (by definition!!!!) The reverse is also true. And no one has ever attributed a vivax infestation to yoelii, nor the other way round. Are you just making stuff up in your head, or what?

P. Yoelii and P. vivax are two different species of the genus Plasmodium. The first occurs only in the Congo basin and only infests rats and mice, never humans. The latter affects humans, but never rats or mice.

Lions and jaguars both belong to the genus Panthera, but are two different species. Do you get it now?

Based on your previous posts, it sounds like you may have the odd idea that P. yoelii is a “carrier” or “vector” of P. vivax? Do you believe that?
-
3. Steve: “said, “You do not even understand why Decadron is contraindicated in cerebral malaria, do you?”
IL-10 and TGF-β are negatively effected. They regulates cytokines. This can cause an infection. Which will attack the kiddies. can cause swelling and blood clots (low platelets.)”
-
Me:
A. IL-10 and TGF-β *are* cytokines, not “regulators of cytokines”.

B. Cytokines do not cause infection. They are an immune system response to infection. Pro-inflammatory cytokines can cause inflammation and the inflammation can cause swelling.

The infamous and often lethal “cytokine storm” in some severe cases of Covid:

https://www.nature.com/articles/s41392-021-00679-0

Cytokine storm in some severe cases of malaria:

https://www.frontiersin.org/articles/10.3389/fcimb.2017.00324/full

4. You have stated several times that Covid patients have “symptoms of cerebral malaria” and stated these “symptoms” were brain fog. I have already established that the symptoms of cerebral malaria are far more serious than brain fog.

It appears you may believe the cytokine storm causes the “loss of grey matter” you talk about, and this results in brain fog. Perhaps, but patients who had mild cases of Covid (no cytokine storm) also later develop brain fog:

https://www.cedars-sinai.org/blog/covid-19-brain-fog.html

5. Your assertion that “P. Yoelii is the parasite genes which are the three spikes on covid” is confusng to me. Do you think the spikes are made up of genes? Um, no, have a look at this:

https://acs-h.assetsadobe.com/is/image//content/dam/cen/98/15/WEB/09815-feature2-virus.jpg/?$responsive$&wid=700&qlt=90,0&resMode=sharp2

Link to image source:
https://cen.acs.org/biological-chemistry/infectious-disease/know-novel-coronaviruss-29-proteins/98/web/2020/04

See the blue squiggly thingy in the center? That is the stand of RNA where all the genetic material is. That is where your little snippet of P. yoelii RNA is located,and is only a tiny percentage of it.

This may he!p you understand better:
https://en.m.wikipedia.org/wiki/Genetic_code

6. Again, you don’t make very clear arguments, so I am left to interpret once more, but as far as I can tell you seem to think a tiny snippet of P. yoelii RNA, comprising an infinitesimal percent of the SARS-CoV-2 virus’ genome, can somehow cause cerebral malaria in humans? Is that correct?
-
Now for the real reasons Decadron is contraindicated in cerebral malaria:

(A) Quality research has proven it is not effective and can, in fact be deleterious. It was used to treat cerebral malaria before this study came out in 1982:

https://pubmed.ncbi.nlm.nih.gov/7033788/

(B) Decadron could reduce host immune response to the parasites. Given that there is a high correlation between density of parasitemia and severity of malaria, this is a valid concern.

As you can read in the study I cited earlier, this is not so much a concern when it comes to Covid:

https://www.news-medical.net/news/20210629/How-does-dexamethasone-therapy-in-COVID-19.aspx

Moreover, it is not administered during the viremic phase of Covid (when it theoretically could be deleterious), but much later during the severe phase when viremia has subsided and inflammatory response is skyrocketing (see this graphic):

https://swprs.org/wp-content/uploads/2020/08/covid-stages.png

And yet you continue to accuse doctors of killing Covid patients with Decadron.


The best I can figure out, you have grabbed onto Perez’s assertion that a fragment of P. yoelii RNA that codes for a fam-a protein is present in the SARS-CoV-2 genome. From there, you somehow jumped to the conclusion that this little snippet of genetic material somehow causes symptoms of another species, P. vivax, in Covid patients, and therefore doctors are killing Covid patients with Decadron. Your assumptions appear to go like this:

P. yoelii genetic fragment —> ? —> symptoms of P. vivax infestation in Covid patients —> ? —> Decadron kills.

It’s like the Underpants Gnomes:
Collect underpants —> ? —> profit.

Unless you can fill in those question marks, I cannot follow your argument.

Are you sure you want to continue posting here that doctors are killing people with Decadron?


74 posted on 08/15/2021 6:54:40 PM PDT by CatHerd (Not a newbie - lost my password)
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To: CatHerd
I said, "The spikes of covid are the parasite that creates malaria."

They are.

YOU said, "“Covid patients have cerebral malaria is utterly nonsensical and unscientific”"
Those two sentences are not the same. What you did was make an assumption that a fragment of the parasite can only carry malaria and nothing else. Though it COULD be related to malaria. Lets try an analogy
You see your friend Caturd's car. You made the assumption that only Caturd drives his car. When actually his wife drove it today. Though it's true Caturd wouldn't let someone drive his car unless they're family

You made a mistake. You can't apologies. It tells me a lot about you.

1. .. Do you see only three spikes?
That is an artist interpretation

said, "do you think the codons discussed in Perez’s paper are spikes? "
No. it wasn't from Perez’s paper. I didn't save those papers showing what looks like. Though it kind of like a triangle. I don't think it's that important and still don't. It's not important how many spikes are on the S1S2 spike protein either though I can tell you it's one spike.
But who cares?

said, "2. Steve: “P. Yoelii is usually attributed the P. vivax malaria infections.”
In my last few posts I gave you at least five links. not counting Wikipedia which it's also on.
I get the impression you don't look.

3. What comes first the chicken or the egg type word games. Yeah my wording could've been more clear here. But every time you talk you want me to write a book or something.
4. “symptoms of cerebral malaria” ....
yes. I was going to get into how malaria can crosses the blood brain barrier. but you got caught up on none sense at least in my opinion.

said, " Decadron could reduce host immune response to the parasites. Given that there is a high correlation between density of parasitemia and severity of malaria, this is a valid concern"

I agree with this statement. Given that covid spikes could be related to malaria. It's could be dangerous to give Decadron to patient with a sever case of covid. Yes the steroid would reduce the storm though it would cause other complications related to blood clotting. Which there is no study on this aspect that I'm aware of. Yes. I believe it was likely our freeper friend was killed by medical malpractice.

yes you can disagree though you never listened to my full argument. You tend to argue over nonsensical statements that you make up.

Which is why I believe you're a disrupter or bad operative.

said, "6. Again, you don’t make very clear arguments"
I never claimed to be perfect.
75 posted on 08/15/2021 8:40:17 PM PDT by Steve Van Doorn (*in my best Eric Cartman voice* 'I love you, guys')
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To: reformedliberal; CatHerd

Hydroxchloroquine also helps against rheumatoid arthritis and lupus and chronic hives etc and of course certain malaria

I take it ....for RA ..it helps ..turn down volume and slows momentum of progression

It is an immunosuppressive agent

It does this by interfering with cell structure communications .....immune cell signaling

Which is likely why it’s also effective against some parasitic diseases growing severe


76 posted on 01/10/2022 7:52:20 AM PST by wardaddy (Do we really think a culture vested in transgenderism can defeat 6000 years of mankind so easily...)
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To: wardaddy

I have read about HCQ being helpful for RA patients, and so glad it’s working so well for you! My late aunt suffered so with RA. Back in the 90s when she had it, there was not as much they knew to do. It is a cruel disease. I’m so sorry you have it!

I’m sure you know to get your eyes checked regularly when taking HCQ longterm, but just in case:

https://www.nature.com/articles/eye2016298

CQ/HCQ “inhibits the action of heme polymerase in malarial trophozoites, preventing the conversion of heme to hemazoin. Plasmodium species continue to accumulate toxic heme, killing the parasite.” Of course the little stinkers developed resistance to it in SE Asia and then in sub-Saharan Africa.

Apparently, it’s being looked at as a cure for giardia, too. I don’t know that much about it, but assume it must work in much the same way on giardia trophozoites. What a rotten stinky disease it is. A dear friend got it, right after recovering from dengue, poor guy. Another dear friend and I cared for him during his illness and agreed you *really* have to care about someone to nurse him through that. Pee-yew!

It also has some antiviral properties, but supposedly fairly weak. I lost interest in it for Covid after MABs became available.


77 posted on 01/10/2022 7:19:36 PM PST by CatHerd (And we are are on earth a little space, That we may learn to bear the beams of love - William Blake)
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To: CatHerd; Pelham

Yes to annual eye exam....my very cute young rheumatologist is on my butt...

Yes I’d taken it before for malaria and dengue 1978-1991

My life of the adventure world wide mostly third world adventure years...before a reckoning and shortly after the start of five children I’ve raised and still raising with a 15 year old at pushing 65

I’ll have raised kids 40 years steady when he turns 21

I took plaquenil as a Covid prophylactic ....my Covid 18 months ago was extremely mild and I’m high risk for sure

Congenital heart issue and pacemaker and lung compromise


78 posted on 01/11/2022 12:27:07 AM PST by wardaddy (Do we really think a culture vested in transgenderism can defeat 6000 years of mankind so easily...)
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To: max americana

My hero.


79 posted on 01/11/2022 12:34:05 AM PST by wardaddy (Do we really think a culture vested in transgenderism can defeat 6000 years of mankind so easily...)
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To: wardaddy

My adventure years were also third world. And war zones. I took doxy for malaria prophylaxis, as I was in an area of multi-drug resistant malaria. It worked pretty well, but in the Land of No Sunscreen I quit taking it for about a week hoping to get over my sunburn and get a nice tan. And boom, I got resistant falciparum. It wasn’t that bad. The cure was much worse than the disease (”toxic doses of quinine”). I was deaf for a couple of weeks from it, but my hearing came back. Yay. Not everyone’s does. And, oh yes, I did get a great tan and went back on my doxy.

Wow, that’s a lot of years of raising kids!

Glad your Covid was mild. I had it in February of 2020 and it was scary bad. Way worse than malaria. I did not go to the hospital, but probably should have. Right now, I either have Omicron or a bad cold. I never get colds, so ...


80 posted on 01/12/2022 3:17:34 PM PST by CatHerd (And we are are on earth a little space, That we may learn to bear the beams of love - William Blake)
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