Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

Osteoarthritis: Realigning bad knees may prompt the body to generate cartilage again
Medical Xpress / Science Translational Medicine / ^ | Apr. 29, 2022 | Delthia Ricks / Tamás Oláh et al

Posted on 04/29/2022 7:24:17 AM PDT by ConservativeMind

Osteoarthritis is a wear-and-tear disorder marked by bone thickening and cartilage degeneration, an excruciatingly painful disability and a major cause of impaired mobility as people age. But scientists have begun viewing this form of arthritis differently with a deeper understanding of the disorder's causes and an eye toward personalized medicine as a treatment option.

Although for decades medical experts have focused on problems such as the pain caused by bone thickening and the disappearance of cartilage, scientists say bone malalignment may play a critical role in osteoarthritis. In a novel clinical study, medical scientists demonstrate how the alignment problem can contribute to osteoarthritis—and they also suggest that correcting it can protect cartilage and reverse its degeneration.

"Although osteoarthritis, a leading cause of disability, has been associated with joint malalignment, scientific translational evidence for this link is lacking," wrote Dr. Tamás Oláh.

But Oláh and a team of researchers launched a two-pronged approach to the problem demonstrating in both animal research and in a human case study that relieving a troublesome misalignment of the joint can help alleviate pain and restore the shock-absorbing role of cartilage in the knee. They report that malalignment of a joint can cause excessive pressure to be placed on it in a manner similar to a condition known as varus malalignment, more commonly known as bow-leggedness. People with severe forms of that condition can suffer cartilage loss and impaired mobility.

By correcting the misaligned joint—unloading pressure on it—the team discovered they could restore function and reduce pain. "We provide evidence of osteochondral recovery upon unloading symptomatic isolated medial tibiofemoral knee osteoarthritis associated with varus malalignment," Olah noted.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: boron; cartilage; il6; knees; ortho; osteo; osteoarthritis
Navigation: use the links below to view more comments.
first 1-2021-24 next last
Only the abstract was available without purchase, but this points to something now being possible to at least somewhat reverse cartilage loss, yet, it’s really just a physical manipulation that causes a response in the body to repair part of itself.

Do note other signs of wear (seemingly the bone itself) did not improve.

Boron is a mineral that has been shown to reduce bone inflammation at the joint-on-joint location, while embedding a super slick surface layer and strengthening the bone.

A prior study back in January posted showed what doctors have seen as an inflammatory marker, IL-6, is fundamental to regeneration of cartilage through its direct influence on STAT3. I think I posted that one.

1 posted on 04/29/2022 7:24:17 AM PDT by ConservativeMind
[ Post Reply | Private Reply | View Replies]

To: ConservativeMind
This was it:

Arthritis-related gene also regenerates cartilage in joints and growth plates

https://medicalxpress.com/news/2022-01-arthritis-related-gene-regenerates-cartilage-joints.html

2 posted on 04/29/2022 7:25:35 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Pete from Shawnee Mission; Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ...

The “Take Charge Of Your Health” Ping List

This potentially high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Now keeping a new list (“Common/Top Issues”) for conditions expected to only concern at least 1% of the population. Ask to be on either the “Common/Top Issues” or “Everything” list.

Please email or private message me if you want on or off of a list and of which list you desire.

3 posted on 04/29/2022 7:26:30 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

This was the thread, here:

https://freerepublic.com/focus/f-chat/4058928/posts


4 posted on 04/29/2022 7:27:46 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
[ Post Reply | Private Reply | To 2 | View Replies]

To: ConservativeMind

Bkmk


5 posted on 04/29/2022 7:28:37 AM PDT by sauropod ("We put all our politicians in prison as soon as they are elected. Don’t you?" Why? "It saves time.”)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

I’ll believe it when I see it.


6 posted on 04/29/2022 7:29:43 AM PDT by Scarlett156 (On the way to #ScientologyPause we enacted #DisneyPause. A thing of beauty. You're welcome.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

They tried it with my wife’s knees, both of them, also paid for the injections of Hyaluronic acid, or rooster comb, as well.

Trying to realign it just made what was left on the other side wear that much faster, some relief of pain at first, but still ended up with both replaced.

I will say this, watching what my wife went through compared to my hip made me realize how lucky I was. I had my hip replaced on a Monday, my birthday actually, sent me home Tuesday, sat around the house Wednesday and Thursday and on Friday said screw it and went back to work. 30 days after I was up to a mile a day on top of my regular work movements with no problems, she is still fighting back 6 months later with stiffness and pain again.


7 posted on 04/29/2022 7:37:04 AM PDT by Abathar (Proudly posting without reading the article carefully since 2004)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

Thank you very much for this post. My knees have been bone-on-bone for years now due to osteoarthritis. However, finally, I’m finally going in for bi-lateral knee replacement in a couple of weeks. Doc sez I’ll get most of my mobility back. It’ll be worth the discomfort. I hope.


8 posted on 04/29/2022 7:40:32 AM PDT by Afterguard (Deplorable me! )
[ Post Reply | Private Reply | To 1 | View Replies]

To: Abathar

Yeah, I’ve done the shots for several years and they provide relief for maybe a week, max.


9 posted on 04/29/2022 7:43:21 AM PDT by Afterguard (Deplorable me! )
[ Post Reply | Private Reply | To 7 | View Replies]

To: ConservativeMind

My wife eliminated osteoarthritis in her shoulders & in her hands by eating only meat & drinking water over 3 years ago. She continues to eat this way & enjoys full range of movement without any discomfort of any kind. Stop eating inflammatory garbage & the body will heal!


10 posted on 04/29/2022 7:48:34 AM PDT by TheStickman (#MAGA all day every day!)
[ Post Reply | Private Reply | To 1 | View Replies]

To: TheStickman

Wow, interesting. Thank you.


11 posted on 04/29/2022 7:52:38 AM PDT by Quilla
[ Post Reply | Private Reply | To 10 | View Replies]

To: Afterguard

I wish you good luck. I cannot imagine having both knees done at the same time. Although, at least they will both heal together. Take good care of the wounds, rub in vitamin E oil three times a day. It will help with your mobility.


12 posted on 04/29/2022 7:57:59 AM PDT by PUGACHEV
[ Post Reply | Private Reply | To 8 | View Replies]

To: ConservativeMind
This was the important stuff on osteoarthritis concerning boron, also previously posted:

Nothing Boring About Boron

https://freerepublic.com/focus/f-chat/3761669/posts?page=39#39

13 posted on 04/29/2022 8:02:29 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Afterguard

I have another suggestion for you: ditch your old sneakers. They have molded themselves to your old gait and will hamper your recovery now that your legs are straight. Buy a pair of Hoka walking shoes. They are marvelously cushioned and very stable - and expensive. They’ll help you learn to walk in a straight line again.


14 posted on 04/29/2022 8:18:36 AM PDT by PUGACHEV
[ Post Reply | Private Reply | To 8 | View Replies]

To: PUGACHEV

Good advice!


15 posted on 04/29/2022 8:20:37 AM PDT by nascarnation (Let's Go Brandon!)
[ Post Reply | Private Reply | To 14 | View Replies]

To: PUGACHEV

Great suggestion, but I’d talk to a podiatrist first. Make sure you know the best footwear to get for you. What mine recommemded to me is not what the salespeople tried to sell me. I went with my doc’s recommendation and my knees, and one ankle, are a lot less painful.


16 posted on 04/29/2022 8:23:15 AM PDT by mewzilla (We need to repeal RCV wherever it's in use and go back to dumb voting machines.)
[ Post Reply | Private Reply | To 14 | View Replies]

To: mewzilla

By all means follow your doctor’s advice. It was mine who recommended the Hokas. I had never heard of the brand before.


17 posted on 04/29/2022 8:30:30 AM PDT by PUGACHEV
[ Post Reply | Private Reply | To 16 | View Replies]

To: Afterguard

My 88 year old father’s knees are bone on bone. Couple years ago his doctor recommended replacement of both of his knees. Doctor said he had done a knee replacement on a 93 year old patient. I think he would be up for it but it means my mom would be by herself for a month or two.


18 posted on 04/29/2022 8:40:15 AM PDT by Mean Daddy (Every time Hillary lies, a demon gets its wings. - Windflier)
[ Post Reply | Private Reply | To 8 | View Replies]

To: PUGACHEV

Thanks for your kind remarks. The surgeries will actually take place a couple of weeks apart, i.e., right knee first then left followed by a couple of weeks. Doc says it will give him/me a bit of insight on the recovery will go. I’m not exactly looking forward to it, but I’m even less looking forward to going thru the rest of life with what has become severely limited mobility (in my opinion).

As for the shoes I’ll look into them. Oddly enough the last couple of years I’ve found that Birkenstock sandals and shoes are most comfortable for me. I used to laugh at Birkenstock wearers, but not anymore :-)


19 posted on 04/29/2022 8:40:53 AM PDT by Afterguard (Deplorable me! )
[ Post Reply | Private Reply | To 14 | View Replies]

To: Abathar
I will say this, watching what my wife went through compared to my hip made me realize how lucky I was. I had my hip replaced on a Monday, my birthday actually, sent me home Tuesday, sat around the house Wednesday and Thursday and on Friday said screw it and went back to work. 30 days after I was up to a mile a day on top of my regular work movements with no problems, she is still fighting back 6 months later with stiffness and pain again.

Every single person I've ever talked to about the subject has said the same thing. Hip replacement, no big deal. Knee replacement, very painful recovery. Fortunately, at 67 I have neither hip nor knee problems. I seem to have a very robust skeletal system.

20 posted on 04/29/2022 9:18:05 AM PDT by AlaskaErik (In time of peace, prepare for war.)
[ Post Reply | Private Reply | To 7 | View Replies]


Navigation: use the links below to view more comments.
first 1-2021-24 next last

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson