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Antibiotics after breast cancer linked to poorer survival, study finds
Medical Xpress / Stanford University Medical Center / Nature Communications ^ | April 21, 2023 | Krista Conger / Julia D. Ransohoff et al

Posted on 04/22/2023 7:48:17 PM PDT by ConservativeMind

Women with triple-negative breast cancer who received multiple antibiotic prescriptions within three years after their cancer diagnosis were more likely to experience disease recurrence and to die from their cancer than those who took fewer courses of the drugs, according to a study. The effect on survival was not due to differences in cancer severity, the study showed.

The risk increased substantially with the total number and types of antibiotics prescribed for each patient.

"Each additional antibiotic increased the risk of death between 5% and 18% relative to patients who weren't prescribed antibiotics," said Julia Ransohoff, MD.

The researchers found that treatment with antimicrobials was associated with a decrease in the numbers of an immune cell called lymphocytes circulating in a patient's blood.

The researchers believe the link between antimicrobials and lymphocyte numbers lies in the gut.

"We've long known that the gut microbiome plays a role in shaping the immune system," Ransohoff said.

This study is the first to correlate antimicrobial use with both the number of circulating lymphocytes and overall cancer survival.

The researchers found that 20% of the women who were not prescribed antimicrobials during the study died. In contrast, 23% of the women who had ever received antimicrobials died. Ransohoff and her colleagues found that the risk of death from breast cancer increased not just with the total number of prescriptions a woman had received since diagnosis, but also with the number of unique drugs to which she was exposed (amoxicillin versus tetracycline, for example).

The association between antimicrobial use and an increased risk of death lasted about three years after the women's cancer diagnoses; the risk gradually decreased in years four and five. Further analysis showed the association was not due to how sick the patients were when they received the drugs.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: antibiotics; breast; cancer; jimknowsdonors
As the association appeared to weaken after the third year, it makes it sound like the gut bacteria took that long to recover.

This could mean a variety of probiotics and cultured foods could be of help, as this study showed no active attempt to recover the bacteria.

1 posted on 04/22/2023 7:48:17 PM PDT by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

2 posted on 04/22/2023 7:49:38 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Bookmark


3 posted on 04/22/2023 7:55:54 PM PDT by ObozoMustGo2012
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To: ConservativeMind

Lovely. Since my mastectomy in 2014 I’ve taken amoxicillin and cipro at times. 😕


4 posted on 04/22/2023 8:14:48 PM PDT by MayflowerMadam
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To: ConservativeMind

How exactly does breast cancer kill? Breasts are not necessary for survival. Total mastectomies are done and the patient lives many healthy years. Cancer in vital organs such as pancreas, brain, liver, lungs etc is obvious killer.


5 posted on 04/22/2023 8:22:06 PM PDT by entropy12 (Food is most popular anxiety drug, exercise is the least popular.)
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To: MayflowerMadam

Please keep active and you will live a long time.


6 posted on 04/22/2023 8:22:54 PM PDT by entropy12 (Food is most popular anxiety drug, exercise is the least popular.)
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To: entropy12

They metastasize and that is how women die.

It’s the same with prostate cancer. Men don’t have to have a prostate, yet they die from metastasis.


7 posted on 04/22/2023 8:29:02 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: entropy12

“Please keep active and you will live a long time.”

It’s hard to be very active with certain health issues, but Mom turns 99 this year so maybe her genes will give me some extra juice. Dad lived to 87.


8 posted on 04/23/2023 3:29:16 AM PDT by MayflowerMadam
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To: entropy12

It spreads to those vital Organs particularly the brain.


9 posted on 04/23/2023 3:58:16 AM PDT by Chickensoup (Genocide is here. Leftist extremists are spearhheading the Genocide against conservatives. )
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To: Chickensoup

Okay that explains it
Breast cancer did not kill all by itself.
Brain or lungs got it from breast and was the cause of death.


10 posted on 04/23/2023 7:31:47 AM PDT by entropy12 (Food is most popular anxiety drug, exercise is the least popular.)
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To: entropy12

they don’t give antibiotics for cancer but if you are prone to infections for other reasons the return of cancer and hospitalizations may be more of a cause than the antibiotic use, 250,000 deaths a year are caused by medical ooopsies. they have to blame something.


11 posted on 04/23/2023 10:34:29 AM PDT by bdfromlv (Leavenworth hard time)
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