Posted on 07/07/2023 8:42:50 PM PDT by ConservativeMind
Around 60,000-100,000 Danes suffer from a form of chronic diarrhea called bile acid malabsorption or bile acid diarrhea.
It is a chronic condition characterized by frequent and sudden diarrhea more than 10 times a day.
"A lot of people with chronic diarrhea don't realize that they suffer from bile acid diarrhea and what has caused it. This is a result of lack of knowledge among healthcare workers and the relatively complex and expensive—and for the patient difficult—process of diagnosing the disease," says Filip Krag Knop.
The new method means that doctors should be able to determine whether the patient has bile acid diarrhea based on a simple blood sample. They focus on molecules known as metabolites in the blood.
Which treatment?
The researchers analyzed blood samples from 50 patients and they quickly realized that the samples—and patients—could be divided into two groups.
The doctors studied the effect of two different treatments: the conventional treatment involving bile acid sequestrant colesevelam and a new treatment involving liraglutide, which is normally used to treat type 2 diabetes and severe overweight.
"What is interesting is that the metabolites in the patients' blood divided them into two groups: one that responds well to colesevelam and one that responds well to liraglutide. This suggests that we should be able to say which treatment is the most effective by analyzing the patient's blood at the time of diagnosis," says Jesper Bøje Andersen.
The clinical study showed that colesevelam treatment eased the bile acid diarrhea symptoms of 50 percent of the patients, while liraglutide treatment eased the symptoms of 77 percent of the patients.
The majority of cases of bile acid diarrhea is diagnosed at a very late stage or never diagnosed at all.
(Excerpt) Read more at medicalxpress.com ...
Heads up!
The author of the study has a familiar name.
Why does that name sound …..
Sounds like a condition in the White House. Time to rid the Bidens out.
Wow, treated with Victoza or Saxenda? Interesting!
PING for later.
try lactaid. cheaper than drugs.
bkmk
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