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Heart attack survivors who skip daily aspirin may have higher risk of recurrence
UPI ^ | AUG. 22, 2023 / 12:36 PM | By Denise Mann, HealthDay News

Posted on 08/22/2023 11:42:30 AM PDT by Red Badger

Those who don't take daily low-dose aspirin consistently after a heart attack are more likely to have another heart attack, stroke or die compared with their counterparts who consistently take aspirin, a new study shows.

If you've had a heart attack, your doctor likely told you to take a low-dose aspirin daily to stave off a second heart attack or stroke, but most people don't follow through with this advice over the long-term.

Those folks who don't take daily low-dose aspirin consistently are more likely to have another heart attack, stroke or die compared with their counterparts who consistently take aspirin, a new study shows. Aspirin keeps platelets from clumping together, which can help prevent or reduce the blood clots that can cause heart attacks and strokes.

"Most people should be on lifelong aspirin after a heart attack," said Dr. Deepak Bhatt, director of Mount Sinai Heart and professor of cardiovascular medicine at the Icahn School of Medicine in New York City.

"Long-term adherence to medication is a problem worldwide, including in the USA, and this is true even for inexpensive drugs such as aspirin, which can be life saving in heart attack patients," said Bhatt, who had no role in the research.

The study was led by Dr. Anna Meta Kristensen of Bispebjerg and Frederiksberg Hospital in Frederiksberg, Denmark.

The researchers followed more than 40,100 people aged 40 or older who had a first-time heart attack from 2004 through 2017. The study team checked up on aspirin use two, four, six, and eight years after their heart attacks to see who was still taking daily aspirin regularly. Anyone using other blood thinners was not included in the study.

Denmark keeps a national registry of medication use including aspirin. People on aspirin for 80% or less of the time were considered to be non-adherent or not taking aspirin as prescribed. By contrast, folks who took aspirin more than 80% of the time were considered adherent.

People stopped consistently taking aspirin over time. At two years, 90% of heart attack survivors were still taking daily aspirin consistently, and this fell to 84% at four years, 82% at six years, and 81% at eight years, the study showed. People who didn't take aspirin consistently were more likely to have another heart attack, a stroke or die at all follow-up points. At four years, the risk for nonadherent patients was 40% higher compared to patients who took low-dose aspirin as prescribed.

The research was scheduled for presentation Aug. 25 to 28, at the European Society of Cardiology meeting in Amsterdam. Findings presented at medical meetings should be considered preliminary until published in a peer-reviewed journal.

"This study emphasizes the importance of correctly taking aspirin after experiencing a first cardiovascular event," said Dr. Silvia Castelletti, a cardiologist in Milan, Italy. "Doing so reduces the chances of having another heart attack, as well as the risks of stroke or death," said Castelletti, who has no ties to the new research.

The study wasn't designed to say why aspirin use wanes over time, and it cannot prove causation.

However, "patients often forget to take aspirin if they are taking multiple medications," Castelletti said. "Additionally, some patients may experience gastrointestinal issues related to aspirin and choose to stop taking the medication on their own."

While aspirin can lower the risk of heart attacks and strokes, it can also increase the risk of gastrointestinal (GI) bleeding and stomach ulcers. "To minimize these risks, it is recommended to take aspirin during a main meal and regularly use gastroprotective medications," she said. Proton pump inhibitors, such as Nexium, Prevacid and Prilosec, can reduce the GI side effects of aspirin.

It's important to note that not every heart attack survivor can or should take aspirin to prevent a second heart attack. "If a patient is allergic to aspirin, it should not be used in their therapy after a heart attack," Castelletti said.

There are many reasons for not adhering to aspirin recommendations, said Bhatt. "At the time of a heart attack, patients are not feeling well and are focused on doing whatever is necessary to get better," he said. As the time from the heart attack increases and they feel well, there may be less motivation to continue taking preventive medicines.

Unfortunately, this behavior puts them at an increased risk of another heart attack, he added.

A related study published in Tuesday's issue of the Journal of the American Medical Association showed that daily aspirin use after a heart attack is lacking across the globe. Fewer than half of all people worldwide who have had a heart attack or stroke take daily low-dose aspirin.

And there hasn't been much of a dent made in these statistics in the past decade.

"We know aspirin use is low overall so we need to find ways to intervene at the patient-provider-level to increase use," said study author Dr. Sang Gune K. Yoo. He is a fellow in the cardiovascular division at Washington University School of Medicine in St. Louis. "The solution is likely multi-factorial and will involve improved patient education on the benefits of aspirin therapy after a heart attack and greater access to aspirin."

He agreed with Castelletti that not every heart attack survivor should take aspirin. "It's important to discuss the risks and benefits with your doctor," Yoo said.


TOPICS: Business/Economy; Food; Health/Medicine; Society
KEYWORDS: aspirin; heartattack; lowdoseaspirin

1 posted on 08/22/2023 11:42:30 AM PDT by Red Badger
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To: Red Badger

Thanks for the reminder, I hadn’t taken it yet today.


2 posted on 08/22/2023 12:43:14 PM PDT by READINABLUESTATE (Make orwell fiction again)
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To: READINABLUESTATE

I take mine every morning before breakfast with my blood pressure meds and vitamin and mineral supplements...........


3 posted on 08/22/2023 12:44:34 PM PDT by Red Badger (Homeless veterans camp in the streets while illegal aliens are put up in hotels.....................)
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To: Red Badger

I no longer trust Big Pharma for ANYTHING. Including 81 mg aspirin.

They lost any respect thru CONVID plandemic.


4 posted on 08/22/2023 1:07:06 PM PDT by C210N (We're at war: Make them have to cheat so much it becomes comical, then ridicule them into oblivion.)
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To: Red Badger

My cardiologist had me on dual anti-platelets, one of which was aspirin. 2 years after the 11 stents, he took me off the aspirin but kept me on Plavix. I’d just as soon stop taking all of it.


5 posted on 08/22/2023 1:10:50 PM PDT by jagusafr ( )
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To: Red Badger

Since I had a heart attack I’ve taken a baby aspirin every morning. Of course, I was taking a baby aspirin every morning before my heart attack, but apparently those don’t count.


6 posted on 08/22/2023 1:37:26 PM PDT by suthener
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To: suthener

And now for the bad news...


7 posted on 08/22/2023 2:18:49 PM PDT by dragnet2 (Diversion and evasion are tools of deceit)
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To: Red Badger

The lowly miracle drug called aspirin. It’s as miraculous as Ivermectin but for other purposes. I have heard Dr. McCollugh talk about taking Nanokinese to eliminate any spike protein from the body, but I am reluctant to take it unless I first talk to my doctor because it has a blood-thinning side effect. I currently take a mini aspirin a day. I have always had a high hemoglobin count and donate blood on a regular basis. Is anyone taking Nanokinese?


8 posted on 08/22/2023 4:38:13 PM PDT by iontheball
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To: suthener

I take two per my cardiologist.........................


9 posted on 08/23/2023 5:14:13 AM PDT by Red Badger (Homeless veterans camp in the streets while illegal aliens are put up in hotels.....................)
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