Posted on 11/12/2023 9:24:32 AM PST by ConservativeMind
Researchers have found a correlation between a compound found in fruits and vegetables and a reduction in the symptoms of endometriosis.
In an article, the researchers outline how flavonoids may be able to help suppress the symptoms of inflammatory diseases like endometriosis. In endometriosis, cells similar to those in the lining of the uterus begin growing in other places in the body, causing inflammation. The painful condition affects millions of women, and there is no cure.
Flavonoids have been associated with anticancer, antioxidant, anti-inflammatory and antiviral medical benefits, but the details of how they work have remained a mystery.
"We were able to show that there is a strong connection between flavonoids and endometriosis," he said. "By eating more foods that contain flavonoids, people are more likely to reduce their chances of endometriosis or reduce the severity of its symptoms."
Flavonoids act in ways similar to some of the drug treatments that Safe's laboratory has developed for diseases like endometriosis.
"We looked at more than 20 flavonoids, and many of them showed an interaction with NR4A1 and NR4A2, which are two of the receptors that we study," he said. "Both of these receptors are involved with regulating inflammation, which is why we target them for treating endometriosis."
The two flavonoids that showed the most influence on NR4A1 and NR4A2 were quercetin and kaempferol, which are commonly found in apples, broccoli, berries, tea, onions and red wine.
"Now we know that these are the flavonoids most likely to help with treating symptoms of endometriosis," Safe said.
"We're not yet to the point of handing out prescriptions for flavonoids to treat endometriosis," Safe said. "What we know right now is that there's a connection between flavonoids and the cell receptors that govern inflammation."
(Excerpt) Read more at medicalxpress.com ...
Table 1 has foods for each substance, in the following paper:
Dietary Quercetin and Kaempferol: Bioavailability and Potential Cardiovascular-Related Bioactivity in Humans
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835347/
I’d never heard of endometriosis. It sounds awful.
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