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New psychedelic-like drugs: All treatment, no trip?
East Bay Times ^ | 12/12/23 | Lisa M Krieger

Posted on 12/18/2023 5:02:28 PM PST by DallasBiff

California scientists race to concoct compounds that could rewire the brain more safely

Since their creation decades ago, mind-altering drugs have remained as unchanged as bellbottoms, tie-dye and patchouli oil.

Now — full of promise and peril — psychedelics are undergoing a makeover. Chemical neuroscientists, many based in Northern California, are redesigning the structures of psilocybin, ketamine, MDMA and other powerful drugs to concoct compounds that they hope will offer mental health benefits with fewer risks.

With advanced tech tools and a deepened understanding of brain chemistry, scientists say the new drugs might succeed where conventional therapies have failed, treating post-traumatic stress disorder, anxiety, depression, addiction and other devastating mental health problems.

“Our goal is to make medicines that are derived from psychedelics that are safer and gentler, more effective and more accessible,” said Matthew Baggott, former director of data science and engineering at Genentech, whose Palo Alto-based startup Tactogen has patented several novel MDMA, or “Ecstasy,” molecules that offer spiritual and personal insights with less heart-racing anxiety and euphoria.

(Excerpt) Read more at eastbaytimes.com ...


TOPICS: Business/Economy; Health/Medicine
KEYWORDS: california; drugs; mebntalhealth; mentalhealth
Figures, it's California.
1 posted on 12/18/2023 5:02:28 PM PST by DallasBiff
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To: DallasBiff

They have some success in PTSD and depression with micro dosing of mushrooms. Funny thing is GOD MADE IT, why screw it up now?


2 posted on 12/18/2023 5:08:15 PM PST by eyeamok
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To: DallasBiff

No trip? No dice.


3 posted on 12/18/2023 5:12:47 PM PST by moovova ("The NEXT election is the most important election of our lifetimes!“ LOL...)
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To: DallasBiff

I would say, try those drugs on Monkeys before giving them to Humans, but I don’t want to light up people like Dr. Fauci again. Try at your own risk, after all else has failed.


4 posted on 12/18/2023 5:13:55 PM PST by lee martell
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To: DallasBiff

The trip IS the treatment.


5 posted on 12/18/2023 5:23:43 PM PST by Pearls Before Swine
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To: DallasBiff

A hit of blotter acid was about $3 when I was in college.

...at least that’s what I was told anyway.


6 posted on 12/18/2023 5:27:04 PM PST by FLNittany (Autotune is jealous of Karen Carpenter)
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To: DallasBiff

The ideal citizen for a dictatorial government would be someone who is perpetually high and happy and safely stoned, the ultimate “bread and circuses.”


7 posted on 12/18/2023 5:39:58 PM PST by piasa (Attitude adjustments offered here free of charge)
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To: DallasBiff

Are you opposed to this research?


8 posted on 12/18/2023 5:40:12 PM PST by Mariner (War Criminal #18)
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To: DallasBiff

“safer and gentler, more effective”

“Safe and Effective.”

We’ve all seen that movie. And not long ago, either.

Man “rewiring” his own brain. What could possibly go wrong?


9 posted on 12/18/2023 5:47:12 PM PST by ProtectOurFreedom (“Occupy your mind with good thoughts or your enemy will fill them with bad ones.” ~ Thomas More)
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To: Mariner

Ask Chandler Bing


10 posted on 12/18/2023 5:47:25 PM PST by Oystir
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To: DallasBiff

They’re developing a form of soma, to put in the water to placate everyone.


11 posted on 12/18/2023 5:48:03 PM PST by struggle
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To: Oystir

He was obviously self medicating with street ketamine.

Hell, whiskey would have killed him just as easy.


12 posted on 12/18/2023 5:50:05 PM PST by Mariner (War Criminal #18)
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To: DallasBiff; sauropod
The hazard from these drugs has been, not the insights, but the sense of certainty in their rectitude.

One should alway TEST an insight, especially if it deviates from tested wisdom. The blessing of the Hebrew Torah is its (IMO) 7,000 years of functional observation and testing. One learns a lot raising generations of animals subjected to controlled culling and breeding, in a closed culture with many generations of oral history.

13 posted on 12/18/2023 5:59:05 PM PST by Carry_Okie (The tree of liberty needs a rope.)
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To: DallasBiff

He’s drawing LSD derivatives.


14 posted on 12/18/2023 7:39:50 PM PST by ifinnegan (Democrats kill babies and harvest their organs to sell)
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To: DallasBiff

California scientists race to concoct compounds that could rewire the brain more safely.

And they said weed would help too homeless people nod.


15 posted on 12/19/2023 8:11:37 AM PST by Vaduz (....)
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To: DallasBiff

But mostly, they want to cure us deplorables of our Faith, patriotism, independent thinking, and addiction to liberty.


16 posted on 12/19/2023 8:14:07 AM PST by NorthMountain (... the right of the people to keep and bear arms shall not be infringed)
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