Posted on 04/04/2024 8:05:24 PM PDT by ConservativeMind
Chronic obstructive pulmonary disease (COPD) is a chronic lung disease with irreversible airflow limitation and a leading cause of death worldwide.
Many studies have reported that the three major nutrients, namely protein, lipids, and glucose, along with nucleotide metabolites, are closely associated with COPD development and progression.
They found levels of lipids are significantly changed in individuals with COPD. Various studies suggested that reversing abnormal lipid metabolism and administration of beneficial lipids might alleviate COPD effects and cardiopulmonary comorbidities.
COPD patients have abnormal levels of amino acids and reduced synthesis capacity of antioxidant carnosine. Some studies suggested supplementation with amino acids and N-acetylcysteine might be able to regulate amino acid metabolism in COPD.
Glucose metabolism is crucial for energy generation and triggering the immune system. However, this metabolism is dysfunctional in COPD patients.
Besides metabolic disorders, microorganisms and their metabolites also play a key role in COPD pathogenesis. The authors found that both pulmonary and intestinal microbes and their metabolites invade and impact the lungs.
The intestinal microbiome of COPD patients consists predominantly of microorganisms that reduce lung function, further establishing the correlation between gut microbiome and COPD. On the other hand, gut microorganisms and their metabolites, like short-chain fatty acids, might play a crucial role in alleviating COPD.
Overall, this study suggested that efficient regulation of lipid, amino acid, glucose, and nucleotide metabolism, along with pulmonary and gut microbial metabolism, is essential for COPD management. Dietary modifications to a low-carbohydrate diet and increasing fiber, antioxidant, and vitamin uptake help in COPD prevention.
Dr. Zhang and Dr. Zhao conclude, "Dietary regulation prevents or suppresses respiratory infections by regulating the intestinal microenvironment, which is surprisingly effective in alleviating the symptoms of COPD. We emphasize that intensified dietary management may be among the most feasible methods to improve metabolism in the body."
(Excerpt) Read more at medicalxpress.com ...
Eating lower carb, increasing soluble fiber sources (increases short-chain fatty acids), getting more antioxidants, vitamins, amino acids (including carnosine and NAC), possible probiotics, and correcting LDL, HDL, and triglycerides can all incrementally help.
BKMRK.
NAC is not only useful for COPD but also will boost your glutathione level which in turn boosts you immune system but should always be taken with twice as much vitamin C.
N-Acetyl Cysteine
N-Acetyl Cysteine (NAC) is a metabolite of the sulfur-containing amino acid, Cysteine. Cysteine is found in high protein foods, N-Acetyl Cysteine is not. N-Acetyl Cysteine is produced within the human body. Cysteine plays a role in the sulfation cycle, acting as a sulfur donor in phase II detoxification and as a methyl donor in the conversion of homocysteine to methionine. Cysteine also helps synthesize glutathione, one of the body’s most important natural antioxidants and detoxifiers. N-Acetyl-Cysteine is the acetylated form of L-Cysteine.
N-Acetyl Cysteine increases Glutathione Levels
N-Acetyl Cysteine is rapidly metabolized to intracellular glutathione. Glutathione acts as a powerful antioxidant in the body. Glutathione also detoxifies chemicals into less harmful compounds. N-Acetyl Cysteine also protects the body from acetaminophen toxicity and is used in hospitals for patients with acetaminophen poisoning. It has also been shown to be effective at treating liver failure from other causes as well.
N-Acetyl Cysteine Chelates Heavy Metals
Heavy metals like lead, mercury and arsenic are detoxified and removed from the body by N-Acetyl Cysteine . It also increases the excretion of zinc and other essential minerals when taken over an extended period. It is therefore necessary to supplement zinc, copper and other trace minerals when taking N-Acetyl Cysteine.
N-Acetyl Cysteine and the Immune System
Glutathione is known to aid in the transport of nutrients to lymphocytes and phagocytes, two major classes of immune cells, and to protect cell membranes. While purified glutathione is available as a dietary supplement, absorption is low, and N-Acetyl Cysteine is thought to be a better method of boosting cellular glutathione levels. N-Acetyl Cysteine is being investigated as a treatment for AIDS.
N-Acetyl Cysteine Breaks up Mucus
N-Acetyl Cysteine cleaves disulfide bonds by converting them to two sulfhydryl groups. This action results in the breakup of mucoproteins in lung mucus, reducing their chain lengths and thinning the mucus, improving conditions such as bronchitis and flu. Double-blind research has found that N-Acetyl Cysteine supplements improved symptoms and prevented recurrences in people with chronic bronchitis. N-Acetyl Cysteine at a dosage of 1,200 mg per day helps to prevent Influenza infection, reduces the symptoms of existing Influenza infection and reduces the duration of Influenza infections.
N-Acetyl Cysteine and Cancer
N-Acetyl CysteineN-Acetyl Cysteine has been shown to reduce the proliferation of certain cells lining the colon and may reduce the risk of colon cancer in people with recurrent polyps in the colon. Its action as an antioxidant and a glutathione precursor may also contribute to a protective effect against cancer.
N-Acetyl Cysteine Cautions
When taking N-acetyl cysteine it is recommended that two to three times as much vitamin C be taken at the same time. Failure to do so may result in more harm than good from taking this product because of the prolonged presence of the oxidized form of L-Cysteine. The vitamin C also helps keep the glutathione that is produced from the Cysteine in its reduced form so that it can continue acting as an antioxidant.
N-Acetyl Cysteine Dosage
Typical dosage recommendations are in the range of 250-1500mg of NAC daily for the majority of therapeutic benefits.
N-Acetyl Cysteine Safety
NAC is considered safe for consumption in its therapeutic dosage ranges. Individual reactions may vary and anyone experiencing adverse symptoms while taking N-Acetyl Cysteine should discontinue it.
What is your source that NAC should be taken with twice as much vitamin c?
.
Read the post where it is spelled out quite clearly. On top of it ascorbic acid is quite beneficial bu itself.
In addition.. Approximately 14 years ago when the H-1 N-1 made its rounds and there was a discussion about getting vaccinated, one Free Republican member suggested to forget about the shot and instead take NAC, no need for a shot. At the time I done some research on NAC and discovered that it can produce some amazing results for many different things. Amongst it the usage in ER’s if someone over doses on acetaminophen to prevent liver damage, that alone should tell you something.
For some reason I used to get colds and my head got all choked up lasting a week to ten days or so, but I started to take NAC and ever since this problem went away and of course it also will boost your Glutathione level making you more resistant to all types of sickness. No wonder a while back FDA tried to restrict public access to this nutrient even so it is pretty harmless even if consumed in somewhat large amounts like 1000 mg to 1500 mg. But it is available again from different sources including Amazon. Some people may find the smell somewhat offensive but it is only natural since it is a sulfur compound and the fresher it is the more potent the smell, what is a good indication.
You should create an “about page”/profile.
First of all thank you for your reply. If I may kindly suggest that you may keep and save my post about NAC for further reference as for many people it has turned out close to a miracle compound helping to improve as well as prevent many ailments. Of course it has a little smell like rotten eggs what is characteristic of a sulfur compound.
I ran into it accidentally around 2009-2010 when H-1 N-1 made it’s rounds and someone on FR suggested NAC instead of being vaccinated as it does an equal or better job. I done my research on it and have been using it ever since in connection with at least twice as much buffered ascorbic acid or vitamin C with good results.
Amongst many of NAC great benefits is its ability to boost ones glutathione level which contributes greatly to an enhanced immune system what may come in handy when those fools in government decide to test and release another virus onto the unsuspecting populace. Take care and be blessed with good health.
It is also supposed to cut the craving for nicotine, making it easier to quit smoking.
I wish I had known 21 years ago when I quit.
I don’t know if it hurts but I take a couple capsules out of the bottle and let them sit out for about 24 hours. It seems to help with the odor.
Bookmark. That’s all new to me. NAC.
I always order NAC in bulk or powder form, the fresher it is the more it reaks of sulfur which is a good indication as this is what you want in order to do what it is designed for. If it no longer smells it usually is old. Never mind the smell, just hold your nose (just kidding) When you use powder you always can mix it in with something else, along with your vitamin C.
Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.