1. The Big Bang is wrong: creation of the entire mass and energy of the universe out of nothing in the first instant of time is a violation of the law of conservation of mass/energy.
2. Evolution is wrong: the orderly sequencing of more than 64 base instructions in DNA code is mathematically impossible in less than 17 billion years without intelligent intervention.
3. General Relativity is wrong: if Gravity was limited to merely the speed of light our planetary orbits would be stacked and shaped like a wedding cake in ever expanding layers as one went out to ever more distant planets from the Sun due to the movement through space of our solar system in the Milky Way's rotational travels through the universe.
...
Whew! Is that enough scientific sacred cows slaughtered for one day?!
nah - i prefer this one above all others:
If the BBT was even slightly correct, the universe ought to be a very large patch of hard and total vacuum located dead-center in a uniformly expanding sphere the surface of which is a uniform-density skim of dust, with no accretions of matter larger than a proton.
that manifestly ain't the case.