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Niacin May Protect Against Alzheimer's (and other mental decline)
Reuters ^ | July 15, 2004 | Anthony J. Brown, MD

Posted on 07/15/2004 9:46:53 PM PDT by FairOpinion

NEW YORK (Reuters Health) - High intake of the vitamin niacin, particularly from food sources, may reduce the risk of Alzheimer's disease and age-related mental decline, according to a new report.

The study in the Journal of Neurology, Neurosurgery, and Psychiatry points out that severe niacin deficiency is known to cause dementia. However, the researchers note that it is unclear if more subtle variations in niacin intake influence the risk of mental deterioration.

"There have been no epidemiologic studies to look at the association between dietary niacin and Alzheimer's disease or cognitive decline," lead author Dr. Martha C. Morris, from the Rush Institute for Healthy Aging in Chicago, told Reuters Health.

Moreover, "animal studies and other studies have really focused on the effects of very high therapeutic dose levels of niacin," not amounts found in a standard diet.

To investigate, the researchers asked several thousand elderly people living in a Chicago community about the types and amounts of food they ate and tested their mental abilities.

The study focused on 815 randomly selected subjects who were free from Alzheimer's disease at the start of the study. After an average of nearly four years, 131 of the participants were diagnosed with Alzheimer's disease.

A high level of total niacin intake seemed to protect against both Alzheimer's disease and cognitive decline. The association was stronger for niacin intake from foods than for niacin taken in vitamin supplements.

"We were surprised to see a fairly strong association between niacin intake from foods and Alzheimer's disease," Morris said. Compared with the lowest intake, the highest intake "was linked to an 80 percent reduction in risk."

In the overall study population, high niacin intake was also linked to a reduced risk of cognitive decline.

Although the finding are provocative, Morris concluded, they will require verification before any changes to current dietary guidelines can be recommended.

SOURCE: the Journal of Neurology, Neurosurgery, and Psychiatry; August 2004.


TOPICS: News/Current Events
KEYWORDS: aging; brain; dementia; deterioration; health; mental
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They keep finding out that vitamins are really important and good for you.
1 posted on 07/15/2004 9:46:53 PM PDT by FairOpinion
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To: FairOpinion

Next story: Researchers discover Alzheimers-jelly bean link.


2 posted on 07/15/2004 9:49:44 PM PDT by formercalifornian (Democrat platform: Hate, hate, hate, hate, tolerance, hate, hate, hate, hate)
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To: FairOpinion

I'll have to look on-line tomorrow to find out which sources provide niacin. Hope I can remember.


3 posted on 07/15/2004 9:52:39 PM PDT by Lijahsbubbe
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To: FairOpinion

Wouldn't you think they would include a list of the most NIACIN rich foods in the story?

There must be more than come to mind immediately.


4 posted on 07/15/2004 9:52:50 PM PDT by 3D-JOY
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To: 3D-JOY

Ever taken niacin? I have for my ears ... to increase circulation which I think this is all about. You get very hot and tingly. Weird feeling.


5 posted on 07/15/2004 9:58:30 PM PDT by BunnySlippers (Must get moose and squirrel ... B. Badanov)
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To: 3D-JOY

Also, my girlfriend takes it for her multiple sclerosis (sp). Same thing ... circulation.


6 posted on 07/15/2004 10:00:00 PM PDT by BunnySlippers (Must get moose and squirrel ... B. Badanov)
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To: Lijahsbubbe
Hope I can remember.

LOL! I know the feeling.

Would you like a reminder FReepmail? :)

7 posted on 07/15/2004 10:00:10 PM PDT by upchuck (Attention politicians of all persuasions: Talk that is not actionable is better left unsaid.)
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To: BunnySlippers
You get very hot and tingly.

There's niacin in FReeping?
8 posted on 07/15/2004 10:00:45 PM PDT by RandallFlagg (<a href="http://www.michaelmoore.com" target="_blank">Hatriotism)
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To: BunnySlippers

Does it help? I'm asking because I have a friend with MS.


9 posted on 07/15/2004 10:02:32 PM PDT by sunshine state
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To: upchuck

Ha ha! Why sure, thanks!


10 posted on 07/15/2004 10:02:44 PM PDT by Lijahsbubbe
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To: Lijahsbubbe; 3D-JOY

http://www.brighamandwomens.org/patient/nutritionRich.asp

Vitamin B3 (niacin)

Lowers cholesterol, protects against cardiovascular disease and may be of benefit in diabetes.

Low-fat meats, poultry, fish, eggs, cottage cheese, peas, broccoli, mushrooms, tofu, brewer's yeast, potato, peanuts, peanut butter

This is a good link -- it also talks briefly about what the other vitamins do and what foods are rich in the particular vitamins.


11 posted on 07/15/2004 10:03:15 PM PDT by FairOpinion (If you are not voting for Bush, you are voting for the terrorists.)
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To: FairOpinion
I've been taking B-complex vitamins for a couple years now. They include 100 milligrams of Niacin, 500% the daily value.

Even though it isn't from food, I highly recommend them. I have much more energy and seem to never get sick.

I know I should watch that word "never" but B-complex has worked wonders for me.
12 posted on 07/15/2004 10:06:00 PM PDT by Bullish
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To: sunshine state

Don't know. But I go to the biggest, best and most prestigious ear hospital in the world ... and if they say take niacin to improve circulation I suspect there is something to it. FYI, you do feel weird for a few days. The feeling wears off after awhile until it's not noticable. If you know someone with MS, it's one of the first things to use since you can find it everywhere over the counter.


13 posted on 07/15/2004 10:06:22 PM PDT by BunnySlippers (Must get moose and squirrel ... B. Badanov)
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To: FairOpinion; BunnySlippers

Vitamin B3 has many effects...only side effects if too heavy a dose as I remember.

I only add nutrients via food. No pills, thank you!

Meat, Eggs etc. Funny, they lower cholesterol and make for clear skin. Everything must be a balancing act.


14 posted on 07/15/2004 10:06:30 PM PDT by 3D-JOY
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To: FairOpinion

Niacin is also supposed to lower cholesterol.


15 posted on 07/15/2004 10:08:17 PM PDT by Keith in Iowa (Michael Moore has made "documentary" a 1-word oxymoron.)
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To: Lijahsbubbe; 3D-JOY
From www.mamashealth.com:

Vitamin B3, also called niacin, is needed for the metabolism of food, the maintenance of healthy skin, nerves and the gastrointestinal tract.

Niacin is found in protein-rich foods. The most common protein rich foods are: meats, fish, brewer's yeast, milk, eggs, legumes, potatoes and peanuts.

If too much niacin is consumed, itching, headaches, cramps, nausea and skin eruptions may occur.

Vitamin B3 is also called nicotinic acid and nicotinamide.

Deficiency of Vitamin B3?

A deficiency of niacin causes the disease, pellagra.

Too much Vitamin B3?

More than 100mg of vitamin B3 can cause flushing, tingling, itching, headaches, nausea, diarrhea and ulcers.

16 posted on 07/15/2004 10:08:30 PM PDT by Pegita ('Tis so sweet to trust in Jesus, just to take Him at His Word ...)
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To: FairOpinion

Thanks!


17 posted on 07/15/2004 10:09:17 PM PDT by Lijahsbubbe
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To: FairOpinion

Here's another link http://www.wholehealthmd.com/hc/doctortips/0,2316,476_892,00.html


18 posted on 07/15/2004 10:09:22 PM PDT by HomersNose
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To: 3D-JOY

I agree regarding balancing act. But some people have deficencies ... or do not eat enough to get the right nutrients. A small supplement doesn't hurt.


19 posted on 07/15/2004 10:09:24 PM PDT by BunnySlippers (Must get moose and squirrel ... B. Badanov)
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To: BunnySlippers

Thank you very much for the information. I'll pass it along to her.


20 posted on 07/15/2004 10:09:50 PM PDT by sunshine state
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