From semi personal experience, I say no. I was far to big, but one of my good friends had to face a girl. He was 123 at the time I believe. He agonized over it for several days...very seriously considered throwing it. He eventually decided to just go and do his best like any other opponent. He pinned her at about 45 seconds. She then accused him of 'inappropriate touching' with claims he was fondling her. I felt so sorry for him.
My semi personal experience was similar. I was wrestling in junior high when a guy on my team was scheduled to go up against a girl. He ended up forfeiting, didn't hear the end of it and ended up quitting. You can argue that everyone involved should have been more mature about it, but these are teenagers we are talking about. Plus, as several posters have pointed out, in our litigation crazy society this just seems to be asking for trouble. Let them develop girls teams for girls who want to wrestle and maybe we can get enough interest in the sport to get in back on the major college radar (since no one seems willing get rid of Title IX).