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Models of eel cells suggest electrifying possibilities[Electric Eels]
EurekAlert! ^ | 02 Oct 2008 | Michael Baum

Posted on 10/08/2008 6:05:25 PM PDT by BGHater

Engineers long have known that great ideas can be lifted from Mother Nature, but a new paper* by researchers at Yale University and the National Institute of Standards and Technology (NIST) takes it to a cellular level. Applying modern engineering design tools to one of the basic units of life, they argue that artificial cells could be built that not only replicate the electrical behavior of electric eel cells but in fact improve on them. Artificial versions of the eel’s electricity generating cells could be developed as a power source for medical implants and other tiny devices, they say.

The paper, according to NIST engineer David LaVan, is an example of the relatively new field of systems biology. “Do we understand how a cell produces electricity well enough to design one—and to optimize that design?” he asks.

Electric eels channel the output of thousands of specialized cells called electrocytes to generate electric potentials of up to 600 volts, according to biologists. The mechanism is similar to nerve cells. The arrival of a chemical signal triggers the opening of highly selective channels in a cell membrane causing sodium ions to flow in and potassium ions to flow out. The ion swap increases the voltage across the membrane, which causes even more channels to open. Past a certain point the process becomes self-perpetuating, resulting in an electric pulse traveling through the cell. The channels then close and alternate paths open to “pump” the ions back to their initial concentrations during a “resting” state.

In all, according LaVan, there are at least seven different types of channels, each with several possible variables to tweak, such as their density in the membrane. Nerve cells, which move information rather than energy, can fire rapidly but with relatively little power. Electrocytes have a slower cycle, but deliver more power for longer periods. LaVan and partner Jian Xu developed a complex numerical model to represent the conversion of ion concentrations to electrical impulses and tested it against previously published data on electrocytes and nerve cells to verify its accuracy. Then they considered how to optimize the system to maximize power output by changing the overall mix of channel types.

Their calculations show that substantial improvements are possible. One design for an artificial cell generates more than 40 percent more energy in a single pulse than a natural electrocyte. Another would produce peak power outputs over 28 percent higher. In principle, say the authors, stacked layers of artificial cells in a cube slightly over 4 mm on a side are capable of producing continuous power output of about 300 microwatts to drive small implant devices. The individual components of such artificial cells—including a pair of artificial membranes separated by an insulated partition and ion channels that could be created by engineering proteins—already have been demonstrated by other researchers. Like the natural counterpart, the cell’s energy source would be adenosine triphosphate (ATP), synthesized from the body’s sugars and fats using tailored bacteria or mitochondria.

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* J. Xu and D.A. LaVan. Designing artificial cells to harness the biological ion concentration gradient. Nature Nanotechnology, published online: September 21, 2008.

Caption: Electric eel anatomy: The first detail shows stacks of electrocytes, cells linked in series (to build up voltage) and parallel (to build up current). Second detail shows an individual cell with ion channels and pumps penetratimng the membrance, The Yale/NIST model represents the behavior of several such cells. Final detail shows an individual ion channel, one of the building blocks of the model.

Credit: Daniel Zukowski, Yale University

Usage Restrictions: Credit line must be included.

Related news release: Models of Eel Cells Suggest Electrifying Possibilities


TOPICS: Miscellaneous
KEYWORDS: cells; eel; electricity

1 posted on 10/08/2008 6:05:26 PM PDT by BGHater
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To: BGHater

Interesting read. Thanks.


2 posted on 10/08/2008 6:11:01 PM PDT by OneWingedShark (Q: Why am I here? A: To do Justly, to love mercy, and to walk humbly with my God.)
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To: BGHater

Wicked cool.

This sort of thing may have many, many serious applications if they can pull it off.

What if it can be scaled up to larger and larger potential? Hmmm...


3 posted on 10/08/2008 6:22:03 PM PDT by Ramius (Personally, I give us... one chance in three. More tea?)
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To: Ramius

Indeed.

I’ve always felt that God gave us the greatest blue prints to create things. We simply have to look around.


4 posted on 10/08/2008 6:24:41 PM PDT by BGHater (The GOP, the new DNC.)
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To: BGHater
Eels? Can "The Matrix" be far behind?

Battery people are those humans who were birthed and raised in the Matrix. Both the Animatrix and the first Matrix movie makes clear that the former battery-people (those people stuck in the Matrix Pods from birth but who now live in Zion) are REPLEAT with electronic parts. Their entire nervous system is wired from head to foot. They have massive amounts of electronics in their brain that allow a virtual reality simulation to completely take over all sensory and perceptual elements. But the purpose of the cybernetic implants is two-fold – it is used to allow perceptual control of the battery people (cyborgs) and its designed to harvest and transfer human-generated energy into electricity. - The Matrix Trilogy: A Man-Machine Interface Perspective


5 posted on 10/08/2008 6:24:42 PM PDT by ricks_place
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To: Ramius
What if it can be scaled up to larger and larger potential? Hmmm..

That was my thought when I saw the headline. Na and K are two of the more abundant elements on the planet. Seems that nanotech is currently sexy, but is it possible to create massive sodium-potassium pumps?

6 posted on 10/08/2008 6:34:55 PM PDT by Mr. Bird
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To: BGHater

Interesting what Mother Nature has come up with in the last 500 million or so years. The article is of the ilk, we can make the desert bloom, cure the sick, raise the dead - just send more money please.


7 posted on 10/08/2008 6:43:04 PM PDT by Citizen Tom Paine (Swift as the wind; Calmly majestic as a forest; Steady as the mountains.)
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To: BGHater

There’s no technology that 40 years and a few trillion can’t bring to maturity.


8 posted on 10/09/2008 11:07:03 AM PDT by TexasRepublic (Brother, can you spare a dime?)
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