[grey_whiskers]

So the fallout is, at first blush, these cells are 'good enough' -- but on closer inspection the cells are not perfect replicas of (so to speak) "real, live, virgin" stem cells, and so they might fail to express certain proteins needed in their final destinations in the same amount or timing as needed, or might produce unwanted proteins, thereby hampering their function?

And this lack of methylation is as far as we can tell, random and therefore not limited to certain genes, which might in principle either be controlled for ("gee, that gene never gets turned on in a liver cell, who cares") ?

BUT such markers -- providing a faint memory of the cells' former role, might make them all the more suited if used to treat / regenerate the same organ from whence they came?

Cheers!

[Gondring]

You might find this interesting, too...more sad news...
http://media-newswire.com/release_1138486.html