CJD disinfection by autoclave:
Standard gravity displacement steam sterilization at 121°C has been studied with different strains of CJD, BSE, and scrapie and has been shown to be only partially effective, even after exposure times of 120 min. As the temperature and exposure time was increased, greater inactivation of the prion agents was achieved (table 5). Although there is some disagreement about the ideal time and temperature cycle [26], the recommendations of 121°C–132°C for 60 min (gravity) and of 134°C for ⩾18 min (prevacuum) are reasonable on the basis of the scientific literature. These methods should result in a decrease of >5 logs, and cleaning should result in a 4-log reduction, which provides a significant margin of safety (brain tissue concentration 105 prions/g) [13]. Other steam sterilization cycles, such as 132°C for 15 min (gravity), have been shown to be only partially effective [36].
I wonder what the source of infection was? Goat? Squirrel? Deer? Sheep?
A family member died last year from CJD - it is a horrible disease. He passed within weeks of diagnosis.
Apparently he didn’t catch inside the US. He traveled globally.
Ping....
The theory is the prion is normally bound to copper. In a copper deficient area, the heavy ferrimagnetic metal gets substituted. The substituted prion is activated by infrasound to make it magnetic. That is when it becomes an agent of damage. The organo phosphate poisons allow the passage of the metal ions into the brain.
It's not a "living" pathogen that is subject to sterilization. It is a chemical toxin. A protein bonded to a very strong magnet.
Purdey's work was inspired by the mad cow outbreaks in the UK where the government required applying an organo-phosphate poison down the back of cattle to deal with warble fly. The military jet aircraft and trucks in the area provided the infrasonic stimulation.
I always tell people that I do not donate blood because anyone receiving my blood will get mad cow disease and die.
I am indefinitely disqualified from donating blood because I lived in Europe for 4 years.
Post to me or FReep mail to be on/off the Bring Out Your Dead ping list.
The purpose of the “Bring Out Your Dead” ping list (formerly the “Ebola” ping list) is very early warning of emerging pandemics, as such it has a high false positive rate.
So far the false positive rate is 100%.
At some point we may well have a high mortality pandemic, and likely as not the “Bring Out Your Dead” threads will miss the beginning entirely.
*sigh* Such is life, and death...
The supposed time-traveler had said a few times that CJD was a big problem in his time. He suggested that people convert to a vegan lifestyle to avoid it. Although I do not believe the story, I first heard about CJD while researching the Titor story.
Just a thought.
Our family member died of CJD while living near Denison, TX in 2008. The medical arena were extremely close hold on any information. Although a 1 in a million disease, another wife seeing his obituary, wrote from just 7 miles away that her husband had died of it.