Totally separate and unrelated problem. True, Baltimore lost manufacturing jobs -- just like all the other Rust Belt cities. And they lost population -- as the mostly white middle class moved west and south to where there were new jobs.
The inner city black population -- a group that was largely unrelated to the manufacturing sector, being mostly jobless in the first place -- was left in charge.
Accordingly, Baltimore is subject to two separate problems:
1. Loss of skilled manufacturing jobs.
2. Unskilled inner city blacks without any economic viability.
What would you employ the inner city population with if not manufacturing?
Is there any other economic activity that can employ thousands of low skilled people? Why else would the rest of the world subsidize manufacturing to export to the US?