Is their feeling about him an unprecedented hatred or fear? No
So far it's less than what other politicians have faced (for example George W. Bush, Dick Cheney).
Disliking somebody isn't always a psychosis or a derangement syndrome.
That may change as the race heats up, but nobody is required to love Ted Cruz and not loving him is hardly a form of madness.
Did you even read the article, or are you just taking the headline to it personally?