With a vampire like Kankles, it’s not good enough to just throw her under the bus.
You need to back the bus over her at least 25 times, throw holy water on her, douse her with lighter fluid and light her on fire, flatten her with a steamroller, and then drive 25 wooden stakes into her heart (that’s assuming she has a heart).
.....and even then, that might not be enough to stop lifetime criminal Kankles.
It might be good to consult Sam and Dean Winchester, they specialize in sending demons to oblivion. (if someone could get her to stand still/pass out, they could surround her in salt and she wouldn’t be able to move. Oh and hell yes to the holy water, it will burn her skin and can only improve on her looks!)