Collins, Murky and Romney are merely the worse of the RINO bunch. There are several other turncoats to worry about.
In other words, we don’t have a comfortably reliable majority.
If PDJT & Mitch could get enough votes for Gorsuch and Kavanaugh, the situation would seem at least marginally better now, IMO.
I have no doubt that Mittens will support Trump’s SCOTUS nominee. Manchin probably will as well. Collins and Murkowski? Doubtful. I feel good about 53.