“What ever happened to Nancy’s parents ?”
Per Wilipedia:
“There was never a sequence of episodes exploring Fritzi’s adoption of Nancy or what happened to Nancy’s parents; she just seemed to appear as Fritzi’s niece and gradually was seen more and more often throughout the 1930s.”
That is a long-lived comic strip!
Poor Aunt Fritzi being stuck with Nancy when she was enjoying a carefree flapper life style. At least Nancy has someone too look after her , Sluggo seems to be a homeless orphan