Épidémie à Coronavirus COVID-19

l’Institut Hospitalo-Universitaire Méditerranée Infection ^ | March 22, 2020 | Professeur Didier Raoult

[StAnDeliver]

"In the current context of the spread of the Covid-19 coronavirus epidemic on French territory and worldwide.

In accordance with the Hippocratic Oath that we have taken, we obey our duty as doctors. We provide our patients with the best care for the diagnosis and treatment of a disease. We respect the rules of the art and the most recently acquired data of medical science.

We have decided :

• For all febrile (fever) patients who come to consult us, to carry out tests for the diagnosis of infection with Covid 19;
• For all infected patients, many of whom are not very symptomatic, have lung lesions on CT scan, we propose, at the earliest stage of the disease, as soon as the diagnosis is made:
• a treatment with the combination of hydroxychloroquine (200 mg x 3 per day for 10 days) + Azithromycin (500 mg on the 1st day then 250 mg per day for 5 more days); as part of the precautions for use of this combination (including an electrocardiogram on Day0 and Day2). In cases of severe pneumonia, a broad-spectrum antibiotic is also used.

We believe that it is not ethical that this treatment should not be systematically included in therapeutic trials concerning the treatment of Covid-19 infection in France."

[StAnDeliver]

Prof. Raoult has done it. The French have a treatment. Raoult has eliminated the control group, and opened the trial to all.

Cuomo is going to run Raoult's protocols starting Tuesday in New York disguised as a 'massive trial' -- it's no trial, it's the actual treatment!

The FDA using Regeneron labs in New York, will provide Cuomo with 10,000 PQL+AZT units -- unironically nearly equal to the amount of cases in New York.

TEVA Pharms makes generics of both PQL and AZT and is donating 6 million doses to US starting now to the end of March. Azithromycin is not in short supply, and is not particularly hard to make (Israeli firm TEVA Pharms makes a generic of AZT too, as do about 10 other companies).

The French won the battle and maybe the war. Vive Didier Raoult! Vive La France!

[ProtectOurFreedom]

Just WOW on PLQ + AZT. Incredible.

Can we lift the “shelter in place” order now?

[House Atreides]

Doctor Fauci and the bureaucratic CDC DO NOT APPROVE! ;-)

Props to these French doctors.

[fhayek]

Didn’t President Trump talk about this? And wasn’t he rebuked? The MSM’s heads will explode if this turns out to be a successful treatment.

[be-baw]

Great post. I’ve seen a lot of good articles lately, but yours is the best I’ve seen in a long time.

Thanks

[Yaelle]

Pas mal ça!

[ProtectOurFreedom]

Yes, President Trump talked about it quite a bit. I think the ruckus was about Fauci being a bit cautious about it and suggesting it could be tested or used per the FDA’s “compassionate use” protocol.

[headstamp 2]

Trials in the field. They’ll get a huge amount of data and save lives.

[headstamp 2]

You can bet Trump has greenlighted this over the bureaucracy like he has so many other things. We are not privy to all the communications flying back and forth.

[House Atreides]

“...TEVA Pharms makes generics of both PQL and AZT and is donating 6 million doses to US starting now to the end of March. Azithromycin is not in short supply, and is not particularly hard to make (Israeli firm TEVA Pharms makes a generic of AZT too, as do about 10 other companies)....”
***********************************
Mylan is reopening a shuttered West Virginia manufacturing facility and expects delivery of product beginning in early April. I’m pretty sure the facility is in Morgantown WV. They have necessary “raw materials” on hand for 50 million tabs. This is important because of the possibility of supply constraints on precursor stock.

http://newsroom.mylan.com/2020-03-19-Mylan-Ramps-Up-U-S-Manufacturing-of-Hydroxychloroquine-Sulfate-Tablets-to-Meet-Potential-COVID-19-Patient-Needs

I believe there are 7 to 8 CURRENT manufacturers of Hydroxychloroquine and more gearing up to manufacture.

[Bigg Red]

Very good.Thanks for posting this.

[catnipman]

“TEVA Pharms makes generics of both PQL and AZT and is donating 6 million doses to US starting now to the end of March. Azithromycin is not in short supply, and is not particularly hard to make (Israeli firm TEVA Pharms makes a generic of AZT too, as do about 10 other companies).”

i appreciate you posting this information; i felt like a lone voice in the wilderness trying to cut through all of the noise of FR ignorance trying to post information like that ...

[Orosius]

I wish FR had a Like button. You’d get ten thousand of them, and that’s just from me!

[StAnDeliver]

Great post! Thank you!

[ProtectOurFreedom]

I’ll bet he is really chewing asses behind the scenes. He’s a no-nonsense boss / CEO. “I don’t give a s$%t!! Just get it done!!!”

[catnipman]

“Doctor Fauci and the bureaucratic CDC DO NOT APPROVE!”

oh, bullshit ...

i’ve listened to every word Dr. Fauci has said on every press conference and he in no way disapproved trying this treatment, he has said only that he wishes to collect systematic data AS THESE TREATMENTS ARE APPLIED ... period ...

[allendale]

The Wusan triad is Fever, Cough and Shortness of Breath. It is now considered diagnostic of COVID-19 infection by the New York City Board of Health. If a patient has Fever and Cough, then the this therapeutic regimen should start before the third point of the triad ,Shortness of Breath, is reached. By then the lungs have already been compromised and the clinical outcome is in doubt. People are concerned that the quinolones and Zithromax prolong the QT interval on EKG and this may lead to serious or fatal arrhythmias. Many therapeutic agents prolong the QT interval. However if a person develops a pneumonia the right side pressures of the heart increase rapidly and while myocardial tissue itself is not a direct target of the virus, the increased strain on the heart due to hypoxemia and increased pressures can in itself lead to arrhythmias.

Quinolones and Zithromax may or may not work. However as of now its the best physicians can offer to patients ill with COVID-19. RNA viruses are bad actors and developing a vaccine is difficult. However until an effective and safe vaccine is developed, this virus will continue to devastate humans and their culture.

BTW believe data out of China at your own risk.

[catnipman]

“Didn’t President Trump talk about this?”

“And wasn’t he rebuked?”

by whom? he certainly wasn’t rebuked by anyone on his team during his press conferences, and i’ve watched very second of every one of them ...

[AndyJackson]

Cuomo is going to run Raoult's protocols starting Tuesday in New York

Tuesday????? Our effing FDA/CDC bureaucrats still at work?! Why not already done.

And yes I get it about the dangers of unsupervised or unrpoven drugs. But if you are in an at risk group the dangers are well known.

[AndyJackson]

Faucci used teh usual bureaucratic dismissal when they have lost control of developments - "it's anecdotal."

I don't know him, but I know this type and they are the bane of scientific progress. I won't give him a pass on his hyper-risk averse bureaucro speak.