Much has been speculated about the ACE receptors that seem to be the portal of entry for this virus. There is the question if the use of ACE inhibitors such as Vasotec or ARBs such as valsartan either alter those ACE receptors and inhibit virus infectivity or do they increase the number of ACE sites an make infection more likely.
By now the CDC should have collected enough data on this issue to advise the public.
I read an article that warned hypertensive patients on ACE inhibitors NOT to get off their medication in case they suspect Corona infection.
I doubt current crop of ARBs (sartans) would do any good on ACE2.
The AACs used on CoV-2’s receptors seem to have been effective on previous generations of CoV (NL63, HKU1 etc.) so there is a good chance this is a real deal, and not just against COVID19.
The spike protein has a cleavage site which reacts with furin-related enzymes on the cell to increase infectivity 1,000-fold compared to the ACE receptor interaction...do these peptides interfere with that?
Secondly, will this compound need to be taken prophylactically forever?
What I’m thinking, is if the compound interferes with the virus binding to cells, will the body develop enough of an immune response, to maintain immunity? Compare the common cold (also a coronavirus) which keeps circling around year after year.