Posted on 04/04/2020 5:56:32 AM PDT by LisaFab
No control group means you don’t know if the drug actually helped anyone, or how much it helped. What is the number needed to treat (NNT) to save one life? 10? 500? You also don’t know if the deaths or ICU admissions could have been from the drug. It can cause arrhythmias and severe hypoglycemia, both of which can be deadly.
Cipro might be another possibility. I don’t know what side effects it may have, but it’s widely used.
Azithromycin and ciprofloxacin have a chloroquine-like effect on respiratory epithelial cells
https://www.mediterranee-infection.com/wp-content/uploads/2020/04/Azithro_COVID.pdf
India has just ordered 100 million doses of the anti-malaria drug. I guess someone thinks it works.
Meanwhile, we have to await the results of “clinical trials”, which may come in several months/years.../s
The outcomes don’t seem any different from what’s been reported from the start.
hydroxychloroquine is being used now both in general use and in multiple clinical trials. But keep spreading false information.
I could be wrong but I don’t believe those in the control group are aware they are in it.
Oh boy, another off-patent cheap antibiotic to replace Z-pack.
BOHICA for the lame rationalizations as to why doxycycline is bad.
I think the article proves that doctors don’t have to wait for clinical studies to use these drugs.
More details from the article:
The FDA has warnings that azithromycin “can cause abnormal changes in the electrical activity of the heart that may lead to a potentially fatal irregular heart rhythm.”
So instead, Alam replaced azithromycin with another decades-old antibiotic that doesn’t pose any known risks to the heart.
“Doxycycline is an anti-inflammatory with properties similar to azithromycin but without the safety concerns and without cardiac toxicity,” he said.
There you go again. The doctor and reporter didn't breathlessly say it was a miracle cure. And they didn't leave any "question" about whether there was a control group. They specifically said that there was no control group.
The answer in the form of a question is a valid way of making a point.
Reinterating an important point that the doctor and reporter made is fine and dandy. Asking a rhetorical question as if the doctor and reporter didn't already make the point is not a valid way to make the point.
“The outcomes don’t seem any different from what’s been reported from the start.”
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Well, the “universe” of his patients was three nursing homes. Almost all would have comorbidities. These were VERY good results considering his patients.
The antibiotic zithromycin is for treating secondary bacterial infections that might occur, not the virus itself. Any broad spectrum antibiotic should be able to work as well as zithromycin.
Are they? We do not have a control group so how would you know?
In NYS (of all places), you have to be in a Cuomo approved study.
It makes complete sense that quinine works.
The reason malaria is so difficult to cure is that the malaria parasite first pokes a hole in a cell’s outer membrane, then sucks out the contents of the cell and then uses the hole to enter the leftover cell membrane and it then wears the cell membrane as camouflage while it goes after the next cell. The body’s antibodies and macrophages don’t attack it because they see it as one of their own.
Quinine breaks down damaged cell membranes.
The covid-19 virus attacks a cell, enters it and uses it to replicate inside. Antibodies and phages can only kill the virus outside of the cell. Since the cell membrane has minor damage from the virus entry point,the quinine breaks down the cell membrane before the virus can replicate and with the cell membrane compromised, antibodies and phages can get at the viruses and destroy them.
Quinine is the perfect medicine for this.
Had a consultation with my Cardio on DOXY.ME. Great and very complete. Aussie Outback medicine gone modern.
Just like Liberal Democrats.
Well they wouldn’t listen to the Jewish Dr. Maybe they’ll listen to the Mohamedan Dr
“Are they? We do not have a control group so how would you know?”
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I understand your point. It’s important that the large, randomized, double blind clinical trials that are now being initiated be completed and their results be part of the basis for future treatment regimens. I at least give this physician props for considering possible complications from including azithromycin in his treatment plan for these particular patients and using a thought out substitute.
I hope he has success with his patients while awaiting results from the clinical trials.
It is always amazing how a virus or parasite often acts like a sentient being.
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