also many atypical pneumonias are bilateral so he is wrong on that front as well. In addition. no one is using high pressure ventilation any longer. If the hypoxia were a defect in blood cells proning would not help nor would increasing O2 delivery but both help in this disease. I have not heard of any broncho alveolar pa age showing pulmonary hemosidrrosis which I would expect with a lot of free iron running around. It may be an Interesting theory and it may be a part of the puzzle but this is not the grand answer.
That was my thought — if the problem is the hemoglobin is broken, how could giving them more oxygen fix that?
I would expect that we could measure for this pretty well, so if this was happening, we’d use something to help with the excess iron, and something to help with oxygen.
I remember reading some research group was making a cell that could carry much more oxygen than hemoglobin, and deliver it somehow to organs, but I haven’t seen any more about it.
That was my thought — if the problem is the hemoglobin is broken, how could giving them more oxygen fix that?
I would expect that we could measure for this pretty well, so if this was happening, we’d use something to help with the excess iron, and something to help with oxygen.
I remember reading some research group was making a cell that could carry much more oxygen than hemoglobin, and deliver it somehow to organs, but I haven’t seen any more about it.
Multiple mechanisms of action, many things going on. I read a couple of months ago, or saw on a YouTube, clinical studies on early cases that having the patient prone on a bed with the head slightly downhill, improved survival by helping the junk to drain out of the alveoli. As far as increasing O2 delivery, if you have both the air sacs filled with mucus, and some % of the blood cells out of commission, then a higher O2 % would help the few remaining blood cells, when they *do* make it to somewhere they can pick up O2, load up with more oxygen. Osmosis, diffusion, mole fraction, yada yada.
>> also many atypical pneumonias are bilateral so he is wrong on that front as well
As well? The author clearly stated malaria involves parasites. So the inaccuracy concerning bilateral symptoms would be the “first front”, no?
I’m not debating the article’s medical merits — only pointing to the malaria misread — and, in no way questioning your medical insights.