What Immunity to COVID-19 Really Means

https://www.scientificamerican.com/article/what-immunity-to-covid-19-really-means/ ^

[BusterDog]

Some takeaways from the article:

"Immunity to seasonal coronaviruses (such as those that cause common colds), for example, starts declining a couple of weeks after infection. And within a year, some people are vulnerable to reinfection."

"But studies of SARS-CoV—the virus that causes severe acute respiratory syndrome, or SARS, which shares a considerable amount of its genetic material with SARS-CoV-2—are more promising. Antibody testing shows SARS-CoV immunity peaks at around four months and offers protection for roughly two to three years."

"Even if the antibodies stick around in the body, however, it is not yet certain that they will prevent future infection. What we want, Bowdish says, are neutralizing antibodies."

". . . a limited number of small studies of cells in laboratory dishessuggest that SARS-CoV-2 infection triggers the production of neutralizing antibodies. And animal studies indicate such antibodies do prevent reinfection, at least for a couple of weeks."

"Research on real-life immunity to SARS-CoV-2 is in its preliminary stages, and uncertainties remain. One study found no correlation between viral load and antibody presence, leading the authors to question the antibodies’ actual role in clearing the virus in humans. In addition, peer-reviewed research on SARS-CoV and preprint studies on SARS-CoV-2 report that some nonneutralizing coronavirus antibodies might trigger a harmful immune response upon reinfection with those pathogens or cross infection with other coronaviruses. Thus, while much of the emerging research is promising, Bowdish cautions against using antibody testing to drive policy until researchers know the proportion of COVID-19 survivors who are producing neutralizing antibodies."

[BusterDog]

Basically, there are tons of questions . . . . .

[BlueStateRightist]

A very good summation of the issues related to antibody testing. Nothing is a given regarding the meaning of “immunity” to SAR-CoV-2. The author correctly points out that the presence of antibodies to a pathogen is not always protective. The antibodies must be “neutralizing”. Further, some infecting viral pathogens don’t give rise to lasting immunity (as little as 2 weeks in some instances), while others do (2-3 years).

[z3n]

If I remember my microbiology (I forgot most of it), each time you get a virus, even if it’s variant but similar, your immune system is going to respond to it more quickly. Your immune system has a memory of sorts for the past patterns that it had to ramp up it’s antibodies for. So basically, you can get the cold and the flu again, over and over, but each time you do, you are less likely for the infection to act as virulently. The very first time you get it is often the worst.

They are saying there are already at least three variations of the current covid19.

If you get one, and then the other, you’re going to fare much better for the second. You may not even notice the second.

Rush Limbaugh was saying that he thinks California got covid19 in December, and developed herd immunity.
I want to posit the theory that New York and the east coast got the Asian and the European variants at the same time, increasing the ability of the covid19 variants to confuse the immune systems in some patients and cause more Lung damage and localized inflammation.

[lepton]

Not surprising. They’ve only had access to the virus for perhaps as long as 2.5 months now. The news cycle may go round and round so fast that if feels like years, but the biology marches at its own speed. Rather difficult to get data on how it is going to act a month after recovery, much less a year, and come to conclusions on that data.

[lepton]

Rush Limbaugh was saying that he thinks California got covid19 in December, and developed herd immunity.

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For this to have happened there would have had to have been at least millions of cases, if not tens of millions. Had there been millions of cases, there would have been at least hundreds of thousands of cases of pneumonia from it, and at least tens of thousands of CT-scans or x-rays for pneumonia checks, and at least tens of thousands of the 80 million CT-scans per year would have been chest scans proximal enough in time to the infected having the disease.

No way remotely does this go undetected. It might have been thousands of doctors discovering it independently, clear cases would have been so pervasive and so obvious.

[kristinn]

Thank you for posting this informative article.

[familyop]

Can You Get Coronavirus Twice? How Long Are You Immune After COVID-19?
https://www.forbes.com/sites/brucelee/2020/03/15/can-you-get-infected-by-coronavirus-twice-how-does-covid-19-immunity-work/

Questions raised over COVID-19 reinfection after Japanese woman develops illness again
https://www.japantimes.co.jp/news/2020/02/28/national/coronavirus-reinfection/

Korean woman reinfected with coronavirus after recovery
https://www.koreatimes.co.kr/www/nation/2020/02/119_285335.html

[null and void]

A virus engineered to have Ebola and HIV spike proteins is unlikely to be easy to develop immunity...

Bring Out Your Dead

Post to me or FReep mail to be on/off the Bring Out Your Dead ping list.

The purpose of the “Bring Out Your Dead” ping list (formerly the “Ebola” ping list) is very early warning of emerging pandemics, as such it has a high false positive rate.

The false positive rate was 100%.

At some point we may well have a high mortality pandemic, and likely as not the “Bring Out Your Dead” threads will miss the beginning entirely.

*sigh* Such is life, and death...

If a quarantine saves just one child's or one old fart’s life, it's worth it.

[familyop]

"Rush Limbaugh was saying that he thinks California got covid19 in December, and developed herd immunity."

The states are each tracing contacts as thoroughly as possible and testing, as evidenced by negative test results for people with symptoms outnumbering positives in some states by more than ten to one. There are undetected cases out there but not millions of them.

Yes, testing has been generally discouraged for many, but that's because they don't want to be harassed by millions of non-infected people demanding to be tested for the purpose of running amok. Which brings us back to the information in the article...

[mewzilla]

It goes undetected a) if most folks are asymptomatic and/or b) Fedzilla says it does.

Remember swine flu...?

[lepton]

It goes undetected a) if most folks are asymptomatic and/or b) Fedzilla says it does.

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Neither of those make it go undetected in that many symptomatic cases.

Remember swine flu...?

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Yes. It was detected, even while not being as different from the regular flus as Wuhan/SARS/MERS are from them. It was detected well before the big outbreak.

[trebb]

But remnants of antibodies may allow the system to “get with the program” a bit quicker and more effectively.

[bgill]

About 3-4 days ago, FOX Maria Bartiroma made a comment about antibodies remain for 30-60 days. This may be what she was talking about.

We’re never going to end this monster. We could have by shutting down the world for 21 days but humans are too wimpy to do that.

Shhh, don’t tell the flubros this is a virus and viruses mutate so “this year’s vaccine” won’t work just like the flu vaccines. It not working is far worse than the flu vaccines not working.

[bgill]

Hopefully, you manage to live through CV the first time, the second time, the third time...

[bgill]

The cancer has eaten up Rush’s brain. No need to listen to his rubbish anymore.

[<1/1,000,000th%]

Actually you want t-cell clones that remain in your bloodstream.

[Greetings_Puny_Humans]

Wtf

Not a good post on your part. I get you’re probably emotional on this topic, but Rush is one of us.

[bgill]

Used to be before his brain was eaten up with cancer. He doesn’t need to be on the air anymore.