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Can the antimalarial drug hydroxychloroquine prevent infection with COVID-19? Multi-site clinical trial investigates Hydroxychloroquine to prevent the virus's spread
EurekAlert! ^ | 05/01/2020 | UNIVERSITY OF CALIFORNIA - LOS ANGELES HEALTH SCIENCES

Posted on 05/01/2020 5:42:13 PM PDT by SeekAndFind

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To: SeekAndFind

Don’t they know it’s not allowed to work?


21 posted on 05/01/2020 9:35:24 PM PDT by TBP (Progressives lack compassion and tolerance. Their self-aggrandizement is all that matters.)
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To: Piers

Piers, would you please provide a link to the message from Luigi Sinigaglia that you posted in #14? I expect the original will be in Italian.


22 posted on 05/01/2020 9:36:32 PM PDT by TChad (The MSM, having nuked its own credibility, is now bombing the rubble.)
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To: Piers

Please ignore my post #22. I found the quote.


23 posted on 05/01/2020 9:44:57 PM PDT by TChad (The MSM, having nuked its own credibility, is now bombing the rubble.)
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To: Left2Right
If you look at the comments below the article at your Il Tempo link, you will see a couple by "Will Bailey." One of them is translated and posted above by Piers.

There is no study of 65,000 patients on HCQ. The article is wrong.

"In the Register of the Italian Society of Rheumatology (CONTROL-19) 150 patients with rheumatological pathologies are included and of these 20 took hydroxychloroquine."

Luigi Sinigaglia - President of SIR

24 posted on 05/01/2020 9:53:21 PM PDT by TChad (The MSM, having nuked its own credibility, is now bombing the rubble.)
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To: euclid216
There is a subsection of Americans that have been taking HCQ all along for R.A. and Lupus, and Malaria.

That's the subject of this WSJ piece:

https://www.wsj.com/articles/hydroxychloroquine-and-other-autoimmune-drugs-dont-fully-protect-against-coronavirus-early-data-suggest-11587222001

I'd like to read it, but it's behind a paywall, and I have not found it posted elsewhere. Besides, the WSJ may be conservative on its editorial page, but its reporting is liberal.

25 posted on 05/01/2020 10:35:00 PM PDT by TChad (The MSM, having nuked its own credibility, is now bombing the rubble.)
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To: TChad

https://www.youtube.com/watch?v=dNmPO2MqYLM

Dr Zelenko talks about preventive use within this discussion.

Maybe lessen the impact so can still develop antibodies to the virus.


26 posted on 05/01/2020 11:40:50 PM PDT by Piers
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To: Piers
Thanks for the link. Interesting that he got the idea to use zinc from the South Koreans.

I wish he had done a lot more testing of his patients.

27 posted on 05/02/2020 12:12:53 AM PDT by TChad (The MSM, having nuked its own credibility, is now bombing the rubble.)
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To: SeekAndFind

If hydroxychloroquine prevents the coronavirus from entering the cell through the ACE-2 receptor, that ends the virus’s life cycle.


28 posted on 05/02/2020 2:59:50 AM PDT by jonrick46 (Cultural Marxism is the cult of the Left waiting for the Mothership.)
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To: elengr

Zinc with hydroxychloroquine causes a two-fold hit on the virus. HCQ prevents the virus from entering the cell where it hijacks the reproductive machinery. It also provides pathways into the cell for zinc. At high levels in the cell, zinc destroys the RNA dependent RNA polymeras, which stops the replication process.


29 posted on 05/02/2020 3:08:27 AM PDT by jonrick46 (Cultural Marxism is the cult of the Left waiting for the Mothership.)
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To: jonrick46

“Zinc with hydroxychloroquine causes a two-fold hit on the virus. HCQ prevents the virus from entering the cell where it hijacks the reproductive machinery. It also provides pathways into the cell for zinc. At high levels in the cell, zinc destroys the RNA dependent RNA polymeras, which stops the replication process.”

Good summary. Many people who eat well, have enough zinc already but it is likely good practice to administer it anyway with the HCQ. Very cheap insurance, like HCQ itself.

The Zpack should only be given if a definite secondary infection has already set in. The HCQ + Zpack can increase risk of (usually non-lethal) cardiac events. Not so much HCQ byitself, with or without Zinc.

BTW, the Korean study above looks quite good!


30 posted on 05/02/2020 3:37:39 AM PDT by Basket_of_Deplorables (Unredact the 99 Collyer Report!!!)
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To: Basket_of_Deplorables

The levels of zinc in the cell required to knock out the virus replication process are not high enough, even if you supplement zinc. However, HCQ opens up these pathways so that the zinc given in the treatment go directly into the cells where they raise havoc with the RNA dependent RNA Polyneras (spelling?).


31 posted on 05/02/2020 12:41:02 PM PDT by jonrick46 (Cultural Marxism is the cult of the Left waiting for the Mothership.)
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To: TChad
Arrrgggggh...I hate fake news....

On the positive, at least it's not just in America anymore...

32 posted on 05/02/2020 5:57:25 PM PDT by Left2Right (Keep America Great!)
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*


33 posted on 05/02/2020 8:22:59 PM PDT by Jane Long (Praise God, from whom ALL blessings flow.)
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