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To: Hojczyk; DoughtyOne; Vermont Lt
We have treated 50+ patients with HCQ and two with remdesivir (a third started today).

Because the disease is taking its own sweet time revealing itself, it's hard to interpret studies that enrolled in March and early April.

It's my opinion now that the window for antiviral therapy is pretty narrow and closes rapidly, the deaths are not due to active viral infection but to the consequences (hypercoagulable state, vascular damage, and cytokine overproduction).

That's by way of saying that antivirals given after the window has closed will do nothing, and studies that include both kinds of patients will yield confusing results.

And, if the triggers for the fatal events are antigen-antibody complexes, the vaccine may prove to be harmful - or not.

Lots of miles to go.

53 posted on 05/19/2020 3:34:31 PM PDT by Jim Noble (Think like youÂ’re right, listen like youÂ’re wrong)
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To: Jim Noble

Wanted to make sure you have seen this.

https://www.latimes.com/world-nation/story/2020-04-13/coworkers-save-coronavirus-doctor


57 posted on 05/19/2020 3:43:49 PM PDT by DoughtyOne (Some of the folks around these parts have been sniffing super flu.)
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