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Hydroxychloroquine fails to prevent COVID-19 in rigorous study
CBS News ^ | 06/04/2020

Posted on 06/04/2020 10:56:57 AM PDT by SeekAndFind

A malaria drug President Donald Trump took to try to prevent COVID-19 proved ineffective for that in the first large, high-quality study to test it in people in close contact with someone with the disease.

Results published Wednesday by the New England Journal of Medicine show that hydroxychloroquine was no better than placebo pills at preventing illness from the coronavirus. The drug did not seem to cause serious harm, though — about 40% on it had side effects, mostly mild stomach problems.

"We were disappointed. We would have liked for this to work," said the study leader, Dr. David Boulware, an infectious disease specialist at the University of Minnesota. "But our objective was to answer the question and to conduct a high-quality study," because the evidence on the drug so far has been inconclusive, he said.

Hydroxychloroquine and a similar drug, chloroquine, have been the subject of much debate since Trump started promoting them in March. Hydroxychloroquine has long been used for malaria, lupus and rheumatoid arthritis, but no large studies have shown it or chloroquine to be safe or effective for much sicker patients with coronavirus, and some studies have suggested the drugs may do harm.

Mr. Trump took a two-week course of hydroxychloroquine, along with zinc and Vitamin D, after two staffers tested positive for COVID-19, and had no ill effects, according to results of his latest physical released by his doctor Wednesday.

Federal regulators have warned against hydroxychloroquine's use except in hospitals and formal studies because of the risk of side effects, especially heart rhythm problems.

(Excerpt) Read more at cbsnews.com ...


TOPICS: Culture/Society; News/Current Events
KEYWORDS: chatforum; covid19; fakenews; hcq; hcqstudy; hydroxychloroquine; prophylaxis; seebs; tds
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To: 1malumprohibitum

this was prophylaxis not treatment. It didn’t work


41 posted on 06/04/2020 11:47:49 AM PDT by Mom MD
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To: SmokingJoe

Sorry. This is not a miracle drug for covid. I would like it to be but it does not work


42 posted on 06/04/2020 11:49:30 AM PDT by Mom MD
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To: SeekAndFind

All this, btw, makes this a bogus study (also very easily done as a fraud):

“The study enrolled people through the Internet and social media, relying on them to report their own symptoms rather than having them tracked in a formal way by doctors. Participants were not all tested for the coronavirus but were diagnosed as COVID-19 cases based on symptoms in many cases. And not all took their medicines as directed.”

Who knows how many actually took the meds, as they only have those who self-reported not to have (though even they seem to have been included in the results).


43 posted on 06/04/2020 11:49:30 AM PDT by 9YearLurker
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To: SeekAndFind

when the fake medical “research” community (which is most of them now) want to denigrate a medicine’s results, they use absolute percentages, such a 12% vs 14%, but when they want to promote a medicine’s results,they use relative results, which in this case would be that the NCQ group had 17% better results than the placebo group, which IS significant ...


44 posted on 06/04/2020 11:54:15 AM PDT by catnipman (Cat Nipman: Vote Republican in 2012 and only be called racist one more time!)
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To: Chauncey Gardiner

I read that NEJM used the same faulty data from Surgisphere that Lancet did.

Lancet is already starting to walk that study back.


45 posted on 06/04/2020 11:55:27 AM PDT by lizma2
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To: catnipman

actually the only results that count are the p value or the number needed to treat. Percentages of any sort are meaningless


46 posted on 06/04/2020 11:59:20 AM PDT by Mom MD
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To: SeekAndFind
After 14 days in the study, 12% on the drug developed COVID-19 symptoms versus 14% in the placebo group, but the difference is so small it could have occurred by chance, Boulware said.

By my math, it reduces the chances of contracting COVID-19 by 17%.

According to the CDC, the flu vaccine was 19% effective in 2014-2015.

47 posted on 06/04/2020 12:07:00 PM PDT by Sooth2222 ("The natives are growing restless")
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To: SeekAndFind

The only reason for that story is that Trump suggested the drug might help.


48 posted on 06/04/2020 12:18:56 PM PDT by I want the USA back (Never forget Justine Damond, murdered by a NON-WHITE, NON-CHRISTIAN cop. (Oh, and no riots))
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To: Mom MD; SeekAndFind
Read this one instead. Real measurements on real subjects. Conclusion: 4 doses of HCQ confers prophylactic effect on Indian health care workers.

https://in.dental-tribune.com/news/new-case-control-study-by-icmr-shows-hydroxychloroquine-can-prevent-covid-19-in-healthcare-workers/

49 posted on 06/04/2020 12:22:14 PM PDT by ScaniaBoy (Part of the Right Wing Research & Attack Machine)
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To: SeekAndFind

Had Covid “symptoms” did they test positive? Were they even tested?


50 posted on 06/04/2020 12:42:44 PM PDT by SueRae (An administration like no other.)
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To: SeekAndFind

If they can’t kill us, they’re going to try and drive us insane


51 posted on 06/04/2020 12:43:49 PM PDT by Pollard (whatever)
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To: SeekAndFind

Take a look at the lead author’s disclosures of conflicts of interest related to funding, which include:

Alliance of Minnesota Chinese Organizations
Minnesota Chinese Chamber of Commerce

I’m sure it’s on the up and up despite the obvious CCP connection. The CCP would never want to pervert science even if it were to Trump’s disadvantage, and no American academic’s research could ever be swayed by either his sources of funding or his political ideology.


52 posted on 06/04/2020 12:46:11 PM PDT by Skepolitic
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To: Mom MD
Sorry. This is not a miracle drug for covid. I would like it to be but it does not work

Yet another idiotic post from the resident fake doctor on FR

So what's new?
But I'll bite.

WHO’s Hydroxychloroquine trials were halted based on a dubious ‘study’ by an unknown company with fake data - OpIndia
13 hours ago · Coronavirus: WHO had stopped HCQ trials based on fake data from a dubious company which employs a sci-fi writer and adult content model. The medical journal Lancet had published a ‘ ...

https://www.opindia.com/2020/06/coronavirus-hydroxychloroquine-study-trial-surgisphere-fake-data-adult-model-lancet-medical/

Lancet faces severe criticism from scientific community: Hydroxychloroquine study is hiding data - Dental Tribune India

5 days ago · More than 100 scientists and clinicians have sent an open letter to The Lancet's editor, Richard Horton, and the paper's authors asking them many uncomfortable questions, but have failed to receive ...

https://in.dental-tribune.com/news/lancet-faces-severe-criticism-from-scientific-community-hydroxychloroquine-study-is-hiding-data/

Even the far left Guardian has finally realised the anti HCQ “study” was fake

Surgisphere: governments and WHO changed Covid-19 policy based on suspect data from tiny US company | World news ...

1 day ago · Surgisphere, whose employees appear to include a sci-fi writer and adult content model, provided database behind Lancet and New England Journal of Medicine hydroxychloroquine ...

https://www.theguardian.com/world/2020/jun/03/covid-19-surgisphere-who-world-health-organization-hydroxychloroquine

There is another thousands more articles from serious publications from all over the world on how fake the anti HCQ study was.

53 posted on 06/04/2020 12:47:41 PM PDT by SmokingJoe
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To: kaktuskid

Political reasons would be my guess.


54 posted on 06/04/2020 12:49:48 PM PDT by kanawa ((Trump Loves a Great Deal (NorthernSentinel)))
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To: kaktuskid

Political reasons would be my guess.


55 posted on 06/04/2020 12:49:48 PM PDT by kanawa ((Trump Loves a Great Deal (NorthernSentinel)))
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To: SeekAndFind

1st question:
Prevent or Cure?

2nd question:
Was the HCQ combined with zinc and the Zpak?

If the ‘scientist’ can’t honestly confirm ‘cure’ and yes to the 2nd question, he can STFU.


56 posted on 06/04/2020 12:52:51 PM PDT by Let's Roll ("You can avoid reality, but you cannot avoid the consequences of avoiding reality" -- Ayn Rand)
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To: SeekAndFind

President Trump didn’t get the virus.

Good enough for me!


57 posted on 06/04/2020 12:56:56 PM PDT by Maris Crane
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To: SeekAndFind

IT’S NOT SUPPOSE TO PREVENT CCP-19, WUHAN, CHINESE VIRUS

It is meant to suppress the symptoms so your body can catch up and you live.


58 posted on 06/04/2020 1:01:57 PM PDT by Vendome (I've Gotta Be Me https://youtu.be/wH-pk2vZG2M)
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To: SeekAndFind
This thread is on the same study you just posted.
Its only 34 posts long if you want to look at it.
http://freerepublic.com/focus/f-news/3851662/posts
59 posted on 06/04/2020 1:06:44 PM PDT by SmokingJoe
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To: SeekAndFind

Hydroxychloroquine is not supposed to prevent the Chinese virus.

If you test positive, it’s supposed to prevent you from getting ill to the point where you needs hospitalization.

80 people....staff and patients at a Texas nursing home tested positive....after taking hydroxyl, 79 were cured and did not need hospitalization.


60 posted on 06/04/2020 1:11:38 PM PDT by july4thfreedomfoundation (Wipe ANTIFA off the face of the Earth. Indict Soros, too...their sugar daddy.)
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