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What to know about the India coronavirus variant causing worries
Washington Examiner ^ | April 24, 2021 | David Hogberg

Posted on 04/25/2021 11:58:15 AM PDT by BeauBo

A new variant of the coronavirus has developed in India, one that is making public health officials worried because it may be causing the country's terrible outbreak and could reduce the efficacy of available vaccines.

The India variant, known as B.1.617 and first identified in October, has been dubbed the “double mutant” variant because it contains two mutations of interest, E484Q and L452R. These are mutations on the spike protein, the part of the virus that attaches to a cell.

"Having two of these mutations which have been seen in other variants around the world are concerning, because there's a similarity in these mutations that confer increased transmissibility, and some of these mutations also result in reduced neutralization, which may have an impact on our countermeasures, including the vaccines," said Maria Van Kerkhove.

E484Q and L452R are known as escape mutations. These types of mutations make it easier for the spike proteins on the virus to evade the antibodies elicited by vaccines and invade cells in the body. Recent research in the journal Cell Host & Microbe found that E484Q was able to evade antibodies in convalescent plasma. An article in Cell recently found that variants containing L452R became more resistant to neutralizing antibodies.

Those attributes raise the fear that a person who's been vaccinated might still be able to carry enough of the mutated virus to infect others, including people who have not been inoculated or have been but have weakened immune systems...

Still, people who have been vaccinated and are infected by a coronavirus mutation are not likely to develop severe COVID-19 or die. Vaccines also elicit a response from another part of the immune system known as T-cells that attack cells infected with a virus... T-cells are able to recognize mutated forms of the coronavirus.

(Excerpt) Read more at washingtonexaminer.com ...


TOPICS: Business/Economy; Culture/Society; Foreign Affairs; News/Current Events
KEYWORDS: b1617; billybear; chinavirus; covid; doublemutant; fearpers; fearthevariant; india; info; omganothervariant; spikeprotein; tellusitsraining; wereallgonnadiesir
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If more evidence emerges that B.1.167 is more transmissible or fatal, the WHO would reclassify it as a “variant of concern.”

India is currently experiencing a surge in COVID-19 cases, especially in the state of Maharashtra, which accounts for half of the country's active cases. On Friday, India experienced a record number of daily cases that exceeded 330,000. Deaths also set a record high of 2,263. Reports of hospitals running out of beds and oxygen are common.

The extent to which B.1.167 is responsible for the current surge is unclear. It has been detected in 10% of the samples that have been genomically sequenced in India. But scientists say more data are needed.

"It seems to be the case, but we cannot say it scientifically. We cannot say so as we have sequenced very small numbers of samples, some 15,000 so far, and we so do not have adequate data to conclude that the B.1.617 variant is responsible for the surge," Dr. Vineeta Bal, an immunologist and a visiting professor at the Indian Institute of Science Education and Research, recently told News 18, a news channel in India.

1 posted on 04/25/2021 11:58:15 AM PDT by BeauBo
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To: BeauBo

There must be bodies or money everywhere.


2 posted on 04/25/2021 12:00:17 PM PDT by blueunicorn6 ("A crack shot and a good dancer”)
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To: BeauBo

No worries, covid is just another flu and will disappear in summer /S


3 posted on 04/25/2021 12:00:32 PM PDT by entropy12
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To: BeauBo

Here is what we need to know about the coronavirus and India. In a country of 1.4 billion people the rate of death is still in line with other countries. About 0.01%.


4 posted on 04/25/2021 12:02:08 PM PDT by Responsibility2nd (Actual FR Quote: “I ain’t getting no Covid Vaccine. I’d rather get Covid and DIE before I get a jab.)
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To: BeauBo

It’s doing what viruses do.


5 posted on 04/25/2021 12:02:11 PM PDT by bgill
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To: BeauBo

India is dirty, overpopulated, unsanitary, and poverty stricken just add in the elderly, compromised, and other diseases they might carry. China is not a friend of India. They may be experimenting on them using bio weaponry


6 posted on 04/25/2021 12:03:07 PM PDT by ronnie raygun
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To: BeauBo

It’s killing the young as much as the old. I have been reading news accounts from India the last week or so.

People who get it start to get sick and 5-8 hours later are dead.


7 posted on 04/25/2021 12:04:01 PM PDT by setter
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To: bgill

Yes that’s right....and some will die....they always do.


8 posted on 04/25/2021 12:04:46 PM PDT by caww ( lawlessness will be increased, the love of many will grow cold. Matt:24:12)
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To: BeauBo

Probably a recent release, Wuhan 2.0


9 posted on 04/25/2021 12:06:12 PM PDT by Cold Heart
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To: blueunicorn6; BeauBo
Follow the money.

This is from Moderna's SEC filing.

https://www.sec.gov/Archives/edgar/data/1682852/000168285220000017/mrna-20200630.htm

Key sentence from the "description of the business" section--

Since inception, we have incurred significant net losses. As of June 30, 2020, we had an accumulated deficit of $1.74 billion. We may continue to incur significant expenses and operating losses for the foreseeable future. In addition, we anticipate that our expenses will increase significantly in connection with our ongoing activities to support our platform research, drug discovery and clinical development, infrastructure and Research Engine and Early Development Engine, digital infrastructure, creation of a portfolio of intellectual property, expansion into global markets, and administrative support.

We do not expect to recognize significant revenue from sales of potential mRNA medicines unless and until we successfully complete clinical development and obtain regulatory approval for one or more of our investigational medicines. If we seek to obtain regulatory approval for any of our investigational medicines, we expect to incur significant commercialization expenses. Our investigational vaccine against the novel coronavirus (mRNA-1273), which is currently in clinical trials, has been developed rapidly to respond to the global COVID-19 pandemic. We are expending significant efforts to further the rapid development of this potential vaccine and expect to continue to do so over the next 12 months. These efforts have required and will continue to require the expenditure of significant funds and the establishment of significant worldwide infrastructure and partnerships.

10 posted on 04/25/2021 12:09:24 PM PDT by grey_whiskers (The opinions are solely those of the author and are subject to change with out notice.)
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To: Cold Heart
Probably a recent release, Wuhan 2.0

Such is my suspicion.

11 posted on 04/25/2021 12:10:02 PM PDT by grey_whiskers (The opinions are solely those of the author and are subject to change with out notice.)
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To: setter
People who get it start to get sick and 5-8 hours later are dead.

Oh give me a break! So for whatever reason Indian politicians have decided to use Covid to seize more power. They are a little late to the party. But they have learned from us...

On an average day 28,000 people from India's population of 1.4 Billion die of something. The fear mongering on this will go on as long as people like you continue to buy into the nonsense.

12 posted on 04/25/2021 12:11:03 PM PDT by fireman15
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To: BeauBo

13 posted on 04/25/2021 12:11:04 PM PDT by grey_whiskers (The opinions are solely those of the author and are subject to change with out notice.)
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To: blueunicorn6
A few of my co-workers are in India. It's heartbreaking what's happening there.

I may catch hell from some here, but I'm praying for India and I hope others are as well.

14 posted on 04/25/2021 12:11:41 PM PDT by usconservative (When The Ballot Box No Longer Counts, The Ammunition Box Does. (What's In Your Ammo Box?))
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To: BeauBo

Is there any information on whether the Indians are prophelacting or symptom treating with HCQ or Ivermectin?


15 posted on 04/25/2021 12:12:46 PM PDT by iontheball
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To: entropy12

Exactly right, just like the common flu as far as seriousness.

https://freerepublic.com/focus/f-news/3953709/posts?page=4#4


16 posted on 04/25/2021 12:13:09 PM PDT by billyboy15 (')
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To: usconservative

What’s happening there?


17 posted on 04/25/2021 12:13:46 PM PDT by blueunicorn6 ("A crack shot and a good dancer”)
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To: grey_whiskers

LOL!!!


18 posted on 04/25/2021 12:20:30 PM PDT by metmom (...fixing our eyes on Jesus, the Author and Perfecter of our faith....)
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To: blueunicorn6

Propaganda 🚨 alert !

At this point they’ve had the coronavirus story going for more than a year

It’s over kids - we don’t care anymore

Show us a real virus 🦠 and we might care!! I’m serious

Covid 19 is complete bullcrap. Compendium of all other viruses

So just ignore ANYTHING Related. Make it END PLEASE. KILL IT !

Just like a. virus 🦠! Kill them !


19 posted on 04/25/2021 12:24:20 PM PDT by Truthoverpower (Arizona !!!! Now the TRUMP TRAIN is getting back on TRACK ! TRUTH! )
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To: setter

It’s killing the young as much as the old. I have been reading news accounts from India the last week or so.

People who get it start to get sick and 5-8 hours later are dead.

::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

Your relatively recent sign up date compels me to ask if
you have any links to back up those statements?


20 posted on 04/25/2021 12:24:42 PM PDT by bramps (It's the Islam, stupid!)
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