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‘One size fits all’ pill for cancer treatment may be on horizon
MSN ^ | June 3, 2022 | Mark Waghorn

Posted on 06/04/2022 10:29:46 PM PDT by Tired of Taxes

A protein that destroys hard to treat cancers has been discovered by scientists - offering hope of effective new treatments.

Experiments on mice and human tissue found it is effective against the most aggressive tumors.

They include those of the breast, pancreas, ovaries and brain. The compound, known as ERX-41, leaves healthy tissue unscathed.

It is one of the most promising breakthroughs to date - offering hope of a "one size fits all"' pill that was once thought impossible.

Results were so encouraging clinical trials are expected to begin in the next few months.

Lead author Professor Ratna Vadlamudi, of the University of Texas, said: "We identified a critical vulnerability in multiple cancers and have validated our findings in multiple cancer cell types and animal models.

"The range of cell lines and xenografts in which the compound has been shown to work is compelling and indicates that it is targeting a fundamental vulnerability in cancer cells."

Xenografts are human tumors grown in mouse models for research purposes. The findings could lead to exciting drugs for cancers that have few effective treatments.

Prof Vadlamudi's lab staff study breast and ovarian cancer with a goal to developing small-molecule inhibitors for tumours that are resistant to current therapies.

In 2017 they identified a compound called ERX-11 that targets the estrogen receptor (ER) protein that drives most breast cancers.

By screening similar chemicals the researchers showed ERX-41 killed ER-positive and triple-negative breast cancers (TNBCs) in petri dishes.

They lack receptors for the hormones estrogen, progesterone and human epidermal growth factor 2 - and are the most deadly.

The researchers then showed ERX-41 also attacked a large number of human tumors grown from several of these cell lines in mouse models.

(Excerpt) Read more at msn.com ...


TOPICS: News/Current Events
KEYWORDS: cancer; cancerresearch; cancertreatment; dostarlimab; jemperli
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This biotech company hopes to start clinical trials in early 2023.
1 posted on 06/04/2022 10:29:46 PM PDT by Tired of Taxes
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To: Whenifhow; null and void; aragorn; EnigmaticAnomaly; kalee; Kale; AZ .44 MAG; Baynative; bgill; ...

sure hope it cures monkeypox, too...

/s


2 posted on 06/04/2022 10:35:30 PM PDT by bitt ( <img src=' 'width=50%> )
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To: Tired of Taxes

How long is the line for clinical trials?

I should probably sign up now so I can get in in a few years.


3 posted on 06/04/2022 10:52:17 PM PDT by VanShuyten ("...that all the donkeys were dead. I know nothing as to the fate of the less valuable animals)
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To: Tired of Taxes

Cost of pill = $1,000,000,000


4 posted on 06/04/2022 10:59:44 PM PDT by Sir Bangaz Cracka (Poor 'lil Travon bees slamming dat white cracka'a head into dat sidewalk causin he be scared)
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To: Sir Bangaz Cracka

Hahaha

Like the people who will control this (if it works) will want money


5 posted on 06/04/2022 11:17:14 PM PDT by algore
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To: algore

Ibrance, from Pfizer, is one pill per month, $10k. Extends like about 10 months. The side effects were too much for my wife. Extreme fatigue, for one.


6 posted on 06/04/2022 11:52:44 PM PDT by JohnnyP (Thinking is hard work (I stole that from Rush).)
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To: Tired of Taxes

Cancer Inc. in America is a huge business. If this becomes reality, it is going to wipe out a lot of that business. It will also put a huge strain on social security and medicare as people live much longer.


7 posted on 06/05/2022 12:55:13 AM PDT by BiglyCommentary
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To: Tired of Taxes

Like all the other cancer cures, this will be the last we hear about it


8 posted on 06/05/2022 1:47:51 AM PDT by roving (Blue Lives Matter More Than Children)
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To: Tired of Taxes

Read later.


9 posted on 06/05/2022 2:05:42 AM PDT by NetAddicted (Just looking)
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To: BiglyCommentary

Bingo my friend. The Dean of the College of Medicine (back in my day) said no one in the industry wants a cure; especially an inexpensive one.


10 posted on 06/05/2022 2:06:23 AM PDT by Chauncey Gardiner
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To: Tired of Taxes
Exercise helps prevent many cancers and helps overcome cancer during treatment...but most adult humans still don't care enough to do it (even just walking).

They want a pill.

11 posted on 06/05/2022 2:41:52 AM PDT by RoosterRedux
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To: Tired of Taxes

Bttt


12 posted on 06/05/2022 2:56:58 AM PDT by Guenevere (“If the foundations are destroyed, what can the righteous do?”)
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To: VanShuyten

encouraging clinical trials, much like the covid vax


13 posted on 06/05/2022 3:41:43 AM PDT by ronnie raygun
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To: Tired of Taxes
Lead author Professor Ratna Vadlamudi...

That's all I need to know... "Hey,Ratna! Go to America. Tell white man he wrong. Not impossible. You cured cancer. Just one sip of your magic water. Make millions."

Like someone else said, last we'll hear of it.

14 posted on 06/05/2022 3:43:52 AM PDT by LibWhacker
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To: Tired of Taxes

As a Cancer survivor this is TOTAL BS!!!! There will NEVER be a magic bullet cure for Cancer with a drug made by Big Pharma. Curing and stopping Cancer comes from eating right, exercise, plenty of sunshine and removing as many toxins from your life as possible.

As a 12 year Cancer survivor I KNOW. If I would have taken the medical route....I WOULD BE DEAD BY NOW!!

For Big Pharma to find a magic cure for Cancer would put the entire Cancer agencies out of business and there is way too much money to be made by keeping the lie going and too many jobs to be lost.

Don’t believe the LIES!!!


15 posted on 06/05/2022 3:51:53 AM PDT by afchief
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To: Tired of Taxes

Cancer feeds on sugar, if you get cancer, remove all sugar from your diet, that includes alcohol. Goodbye cancer, however that is not profitable for big pharma and our medical institutions. Sorry, most of this has been wiped off of the web.


16 posted on 06/05/2022 3:57:19 AM PDT by foundedonpurpose (Praise Hashem, for his restoration of all things!)
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To: Tired of Taxes
For anyone eho wants to geek out, just published...

Targeting LIPA independent of its lipase activity is a therapeutic strategy in solid tumors via induction of endoplasmic reticulum stress

17 posted on 06/05/2022 4:16:14 AM PDT by mewzilla (We need to repeal RCV wherever it's in use and go back to dumb voting machines.)
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To: Tired of Taxes

Free for anyone. Complete with microchips.


18 posted on 06/05/2022 4:23:54 AM PDT by motor_racer ("We're gonna punish our enemies, and we're gonna reward our friends" - Barak Obama)
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To: BiglyCommentary
Cancer Inc. in America is a huge business. If this becomes reality, it is going to wipe out a lot of that business. It will also put a huge strain on social security and medicare as people live much longer.

You just said what I have thought for a long, long time!

19 posted on 06/05/2022 4:54:24 AM PDT by eeriegeno (Checks and balances??? What checks and balances?)
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To: Tired of Taxes

After covid, anyone who trusts pharma is insane.


20 posted on 06/05/2022 5:04:52 AM PDT by exnavy (we are not a democracy.)
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