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Puberty blockers may NOT be reversible and could raise children's risk of fertility problems and even cancer, Mayo Clinic study suggests
Daily Mail ^ | April 6,2024 | By JAMES REINL

Posted on 04/05/2024 12:21:01 PM PDT by artichokegrower

Mayo Clinic experts say puberty blockers can lead to withering testicles, fertility problems and even cancer among the trans kids who take them, in the latest study to raise alarm about transgender medicine.

The findings cast doubt on the 'reversibility' of puberty blockers — a key claim of the trans activists who promote the drugs, saying they only 'pause' puberty and buy time for trans kids to make decisions about their gender.

(Excerpt) Read more at dailymail.co.uk ...


TOPICS: Culture/Society
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Doctors that provide puberty blockers are committing malpractice
1 posted on 04/05/2024 12:21:01 PM PDT by artichokegrower
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To: artichokegrower

Millstone, and deserved.


2 posted on 04/05/2024 12:24:06 PM PDT by mware
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To: artichokegrower

Doctors that provide puberty blockers should jailed


3 posted on 04/05/2024 12:25:54 PM PDT by gibsonguy
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To: artichokegrower

They needed a *study* to come to this conclusion???????????


4 posted on 04/05/2024 12:26:15 PM PDT by metmom (He who testifies to these things says, “Surely I am coming soon.” Amen. Come, Lord Jesus…)
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To: artichokegrower

Go fiddling with the design of the universe, things happen.


5 posted on 04/05/2024 12:26:20 PM PDT by lurk (u)
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To: artichokegrower
Things no patient wants to hear: Doctor to 16 year old trans patient: "Your testicles are withered. But we THINK it might be reversible. But we aren't sure yet. Here, let me show you what we are talking about."


6 posted on 04/05/2024 12:26:57 PM PDT by ProtectOurFreedom (“When exposing a crime is treated like a crime, you are being ruled by criminals” – Edward SnowdenA)
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To: artichokegrower

Remember the old margarine commercial with the punchline: “it’s not nice to fool mother nature?” Well you cannot play god and expect to get away with it.


7 posted on 04/05/2024 12:28:14 PM PDT by Fungi
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To: artichokegrower

I could’ve told you that from established science.


8 posted on 04/05/2024 12:30:25 PM PDT by Skywise
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To: artichokegrower

File suits against the libtards


9 posted on 04/05/2024 12:30:44 PM PDT by NWFree (Sigma male 🤪)
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To: artichokegrower

here is a link to the actual paper

https://www.biorxiv.org/content/10.1101/2024.03.23.586441v1.full

Abstract

Spermatogonial stem cell (SSC) acquisition of meiotogenetic state during puberty to produce genetically diverse gametes is blocked by drugs collectively referred as ‘puberty blocker’ (PB). Investigating the impact of PB on juvenile SSC state and function is challenging due to limited tissue access and clinical data.

Herein, we report largest clinically annotated juvenile testicular biorepository with all children with gender dysphoria on chronic PB treatment highlighting shift in pediatric patient demography in US.

At the tissue level, we report mild-to-severe sex gland atrophy in PB treated children. We developed most extensive integrated single-cell RNA dataset to date (>100K single cells; 25 patients), merging both public and novel (52 month PB-treated) datasets, alongside innovative computational approach tailed for germ cells and evaluated the impact of PB and aging on SSC. We report novel constitutional ranges for each testicular cell type across the entire age spectrum, distinct effects of treatments on prepubertal vs adult SSC, presence of spermatogenic epithelial cells exhibiting post-meiotic-state, irrespective of age, puberty status, or PB treatment. Further, we defined distinct effects of PB and aging on testicular cell lineage composition, and SSC meiotogenetic state and function.

Using single cell data from prepubertal and young adult, we were able to accurately predict sexual maturity based both on overall cell type proportions, as well as on gene expression patterns within each major cell type.

Applying these models to a PB-treated patient that they appeared pre-pubertal across the entire tissue. This combined with the noted gland atrophy and abnormalities from the histology data raise a potential concern regarding the complete ’reversibility’ and reproductive fitness of SSC.

The biorepository, data, and research approach presented in this study provide unique opportunity to explore the impact of PB on testicular reproductive health.


10 posted on 04/05/2024 12:32:16 PM PDT by JSM_Liberty
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To: artichokegrower

Chemical castration.

Literally blocking all testosterone production in the body.

“Doctors” doing this to children are monsters and should be jailed.


11 posted on 04/05/2024 12:32:25 PM PDT by ifinnegan (Democrats kill babies and harvest their organs to sell)
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To: artichokegrower

Doctors have ALWAYS known that you can’t “reverse” the results of puberty blockers. Every day the body’s feminine or masculine development is BLOCKED is lost. It’s not like a song or a movie that you can “pause”, then pick up where you left off. Puberty is a limited window. It can’t be shifted.


12 posted on 04/05/2024 12:33:15 PM PDT by ETCM (“There is no security, no safety, in the appeasement of evil.” — Ronald Reagan)
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To: artichokegrower

We, the taxpayers, will end up paying for all of the healthcare costs. We always do.


13 posted on 04/05/2024 12:36:31 PM PDT by Mr. N. Wolfe
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To: artichokegrower

Nobody but tranny sympathizers ever thought that puberty blicjers were reversible. Our bodies have a small window for puberty. These folks are criminals plain and simple. Monsters really.


14 posted on 04/05/2024 12:37:21 PM PDT by DouglasKC
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To: artichokegrower

Of course they aren’t reversible. Mess with someone’s critical development and you have had it. You can’t go back in time.


15 posted on 04/05/2024 12:38:08 PM PDT by Persevero (You cannot comply your way out of tyranny. )
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To: artichokegrower

Anyone that knows anything about endocrinology knows that when a young person is put on puberty blockers it all can not be reversed. As one’s body matures it is totally dependent on hormonal driven directives to the body. Once one is past early puberty it can not be reversed. A scaple nor drugs will reverse this!

The first part of the Hippocratic Oath is “DO NO HARM.” These physicians have no regard to the oath they take.


16 posted on 04/05/2024 12:44:32 PM PDT by cpdiii (cane cutter-deckhand-oilfield roughneck-drilling fluids tech-geologist-pilot-instructor-pharmacist)
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To: artichokegrower

so crazy people will not be able to get older and reproduce? that’s a win for me.


17 posted on 04/05/2024 12:46:31 PM PDT by ronniesgal (have you even tried to mind your own business?)
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To: artichokegrower

They should require these drugs be randomly tested on the drug companies’ executives’ and the approving judges’ children and grandchildren.


18 posted on 04/05/2024 12:48:18 PM PDT by alternatives?
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To: artichokegrower

Duh. That’s why they want to use them.


19 posted on 04/05/2024 12:48:31 PM PDT by E. Pluribus Unum (The worst thing about censorship is █████ ██ ████ ████ ████ █ ███████ ████. FJB.)
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To: artichokegrower

Josef Mengele
State sponsored sterilization.


20 posted on 04/05/2024 12:53:41 PM PDT by Zathras
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