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Experts Suspect Virus Is Cause of Asian Mystery Illness (SARS Alert!)
Associated Press ^ | March 17, 2003 | Emma Ross

Posted on 03/17/2003 2:35:09 AM PST by Timesink

Mar 17, 2003

Experts Suspect Virus Is Cause of Asian Mystery Illness

By Emma Ross
The Associated Press

Health experts searching for the cause of a frightening outbreak of a deadly flu-like illness in Asia say the culprit is probably a virus, and they are encouraged that some victims appear to be getting better.

More than 150 people have fallen ill, mostly in Hong Kong and Vietnam, over the past three weeks. And experts suspect that another 300 people in China's Guangdong province had the same disease beginning in mid-November.

While experts are unsure precisely what is causing the outbreak, several say their biggest fear is that it is a new and lethal form of influenza.

"If it really is the flu, it could be we have a new organism that could cause a pandemic," said Dr. R. Bradley Sack, director of Johns Hopkins' international travel clinic. "People immediately start thinking of 1917," when a worldwide flu epidemic began that killed at least 20 million people.

So far, the disease has killed nine people - seven in Asia and two in North America. Its rapid spread, and the discovery of two clusters in Canada, caused a rare worldwide health alert to be issued on Saturday.

Health officials in China said Monday that the disease that infected about 300 people and killed five in Guangdong province "seems amenable to treatment," although they stressed there is still no link to cases in other countries.

Asian airports were screening passengers for flu-like symptoms, in the hope of stopping the spread of the disease. Some fearful passengers wore surgical masks or covered their faces to ward off infection.

Experts discounted the possibility that terrorism is the source and believe it almost certainly is a contagious infection that spreads most easily from victims to their doctors, nurses and families through coughing, sneezing and other contact with nasal fluids.

"Nothing about that pattern suggests bioterrorism," said Dr. Julie Gerberding, head of the U.S. Centers for Disease Control and Prevention in Atlanta.

Health officials say it may be several more days before they are able to identify the disease. However, they said several of its features suggest it is caused by a virus, which can often be difficult to pinpoint quickly using standard lab tests.

The illness is being called "severe acute respiratory syndrome," or SARS. The incubation period appears to be three to seven days. It often begins with a high fever and other flu-like symptoms, such as headache and sore throat. Victims typically develop coughs, pneumonia, shortness of breath and other breathing difficulties. Death results from respiratory failure.

The World Health Organization has been aware of the outbreak for about three weeks but issued its global alert this weekend because of concern that the illness would spread to North America and Europe.

Officials said they are encouraged that some recent victims seem to be recovering, although they are unsure whether that is because of the many antibiotic and antiviral drugs they have been given or simply the natural course of the disease.

Dr. David Heymann, WHO's communicable diseases chief, said three or four patients had stabilized enough to be moved out of intensive care Sunday in Hanoi, Vietnam, although all still had breathing problems.

The World Health Organization estimates that perhaps 500 people in all have been sickened if the earlier outbreak in China turns out to be part of the same disease, as they suspect it is.

Ninety percent of the most recent cases have been in health care workers.

The CDC prepared cards that were being given to travelers arriving from Hanoi, Hong Kong or Guangdong province in China, warning they may have been exposed. It recommended they see a doctor if they get a fever accompanied by a cough or difficulty breathing over the next week.

Investigators suspect a virus is involved, because victims do not seem to respond well to standard antibiotics, which kill only bacteria, and because their white blood counts drop. That typically happens with viral infections but not bacterial ones.

Few drugs exist for treating viral diseases and often they must run their course until brought under control by the body's natural immune defenses.

No cases have been confirmed in the United States, but Gerberding said the CDC is checking out a few calls. The North American fatalities were a woman and her grown son who died in Toronto after visiting Hong Kong.

A 32-year-old physician from Singapore suspected of having the disease was taken off an airliner during a stopover in Frankfurt, Germany, on Saturday after being in New York City for a medical conference. He was held in quarantine, along with his mother, who had a fever, and his wife, who remained healthy.

However, on Sunday, the man's physician, Dr. Hanns-Reinhardt Brodt, said he was uncertain the case was SARS; he was treating him for ordinary pneumonia.

Also on Sunday, WHO released a report from the China Ministry of Health on the Guangdong outbreak, which said "the epidemic situation has been controlled and the patients are being cured one by one."

In that outbreak, the Chinese said, 7 percent of patients required breathing tubes, but most eventually got better, especially if they were not also infected with bacteria. The disease seemed to weaken as it passed from person to person.

---

On the Net:

WHO: http://www.who.int/en/

CDC: http://www.cdc.gov/ncidod/sars/

AP-ES-03-17-03 0509EST


TOPICS: Breaking News; Culture/Society
KEYWORDS: atypicalpneumonia; epidemic; pandemic; pneumonia; sara; sars

1 posted on 03/17/2003 2:35:09 AM PST by Timesink
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To: Timesink
Get your Amantadine prophyllactic prescriptions now.
2 posted on 03/17/2003 2:40:41 AM PST by patriciaruth
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To: patriciaruth
Amantadine's for Parkinson's Disease, isn't it?
3 posted on 03/17/2003 2:43:40 AM PST by Timesink (Hi, Billy Mays here for new MOAB! It'll wipe your worst stains right off the face of the planet!)
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To: Timesink
The German reported in this article is in very bad condition.

All of the employees on the flight are in "house quaranteen".

Also, there are two suspected cases in Geneva.

This is being played WAY down in the media. According to the reports here, the disease is transmitted like a cold or whopping cough. They DO NOT know what it is! They have no "cure". It is travelling around the world and seems to be at least significantly contagious. Why is the press not pushing for more??
4 posted on 03/17/2003 3:03:13 AM PST by An.American.Expatriate
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To: Timesink
Amantadine is also used for influenza as treatment and prophylaxis. I think it is only good for influenza A. There are newer, probably better meds...which are also more expensive, natch.
5 posted on 03/17/2003 3:40:24 AM PST by RJCogburn (Yes, it is bold talk.....)
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To: Timesink
The only thing that perks my ears up is te end "The disease seemed to weaken as it passed from person to person."

Diseases don't weaken with transmission.
6 posted on 03/17/2003 4:43:07 AM PST by Bogey78O (check it out... http://freepers.zill.net/users/bogey78o_fr/puppet.swf)
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To: An.American.Expatriate
This is being played WAY down in the media. ... Why is the press not pushing for more??

Don't worry about that. If the press sees a chance to exploit a disease for the fear factor, it will (West Nile virus, for instance).

7 posted on 03/17/2003 5:48:54 AM PST by newgeezer (I'm a native American. Aren't you?)
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To: An.American.Expatriate
I don't know about the press downplaying this...I was surprised to hear Russert ask Colin Powell about the disease on MTP!
8 posted on 03/17/2003 5:59:30 AM PST by marktuoni
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To: Bogey78O
Diseases don't weaken with transmission.

Experts discounted the possibility that terrorism is the source and believe it almost certainly is a contagious infection that spreads most easily from victims to their doctors, nurses and families through coughing, sneezing and other contact with nasal fluids.

I love this. Seems to me like all it would take is half-a-dozen or so martyrs from the religion of peace willingly exposed to the contaminant, and then once contagious, sent on a world-wide shopping spree for 24 to 48 hours.

9 posted on 03/17/2003 6:08:34 AM PST by fivecatsandadog (fur, cryin' out loud...)
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To: Timesink
The illness is being called "severe acute respiratory syndrome," or SARS

M R DUCKS

M R KNOT

O S A R - C M WANGS

L I'LL B

M R DUCKS

10 posted on 03/17/2003 6:55:58 AM PST by martin gibson
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To: Bogey78O
Diseases don't weaken with transmission.

Technically, no. But in effect, yes. Because if a virus is too lethal it kills its host before the host can pass on the virus. Thus as the virus continues to mutate, the less lethal variations are the ones that are spread more widely. It is speculated that the common cold viruses originally were quite lethal, but over time it is the less lethal variations that survived. From a virus survival perspective, it is better to cause only enough injury to spread and no more.

11 posted on 03/17/2003 7:10:47 AM PST by dark_lord
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To: fivecatsandadog
It's just another coincidence.(sarcasm)
12 posted on 03/17/2003 7:28:16 AM PST by sheik yerbouty
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To: newgeezer
Don't worry about that. If the press sees a chance to exploit a disease for the fear factor, it will (West Nile virus, for instance).

Very interesting obseravation. You are absolutley correct.

Yet, it seems the level of hype and exploitation is inversely proportional to the possibility that the disease could actually effect average people.

13 posted on 03/17/2003 7:48:09 AM PST by tallhappy
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To: dark_lord
Makes sense.

But for so many mutations to exist it would have to reproduce at an alarming rate. Because if what you said about the cold virus holds true it took centuries for it to mild down it seems.
14 posted on 03/17/2003 8:58:25 PM PST by Bogey78O (check it out... http://freepers.zill.net/users/bogey78o_fr/puppet.swf)
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To: Bogey78O
Except remember there are hundreds and hundreds of different "cold" viruses. Otherwise we would just get it once as kids and not again, rather than every darn winter. And the cold viruses themselves do continue to mutate as well.
15 posted on 03/17/2003 10:00:11 PM PST by dark_lord
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