Woodward’s paper on the dino bone dna can be found here:
DISP: Bioinformatics LabDINO DNA sequence in the BLAST web form and “BLAST” it. We will use all the default settings, so just press the format button. ...
myweb.dal.ca/js551958/Tutorial/Lab2.html
Well worth reading!
I’ll check it out...thanks for the link!
I did PCR in the mid 90s and it was a real bitch to avoid contamination. I had to bleach almost everything used, even the interior of the pipettes to get rid of the contamination.
Back in 94 the databases were orders of magnitude smaller. Yeast wasn't even sequenced (the first entire genome sequenced- would have made my thesis work easier).
Sequencing was totally different then. The associated paper used radio-labeled nucleotides and ran it on a gel. The sequencing gels were read by hand. Now fluorescent tagged nucleotides are used and the sequence is read directly off the gel by machine. In fact you send off your DNA and primers by FedEx or other courier and the next afternoon you are e-mailed your sequence. Much faster and accurate.
Doesn't prove anything except that dinosaur DNA hasn't been cloned.