Free Republic

For patients with community-acquired pneumonia (CAP), doxycycline is associated with a reduced risk for Clostridioides difficile infection (CDI), according to a study. Ashley L. O'Leary, Pharm.D., from the Veterans Affairs Western New York Healthcare System in Buffalo, and colleagues conducted a retrospective analysis in hospitalized patients in Veterans Affairs Hospitals across the United States to examine whether doxycycline is associated with reduced CDI risk. During the study timeframe, about 156,107 hospitalized patients received care at a Veterans Affairs Hospital and were diagnosed with CAP. The researchers found that compared with azithromycin, doxycycline used with ceftriaxone for the treatment of pneumonia...

A study reveals that the use of doxycycline may help protect against Clostridioides difficile (C. diff) infection for some patients with pneumonia. Specifically, study authors found that for hospitalized patients with community-acquired pneumonia who had experienced C. diff infections in the prior year, the use of doxycycline, instead of the more commonly used azithromycin, reduced the development of new C. diff infections by 45%. More than a third of patients who suffer a C. diff infection will go on to have another in the future. For patients who are admitted to a hospital with pneumonia, clinical guidelines typically recommend the...

As rates of sexually transmitted infections continue to skyrocket across the United States, a growing number of physicians are prescribing a commonly used antibiotic as a way to prevent chlamydia, gonorrhea and syphilis infections in gay and bisexual men and transgender women. Doxycycline is a class of medications traditionally used to treat bacterial STIs after someone has been infected. Yet recent research suggests that one 200mg dose of the drug can be effective in preventing such infections among men who have sex with men if taken within 72 hours after unprotected sex.

Elaborating on the effective methods being followed for treating COVID-19 across the globe, Shashikanth Manikappa, a specialist cardiac anaesthetist working at Monash Health in Melbourne, Australia, has strongly advised what he termed Quadruple Therapy involving four medicines — Ivermectin, Doxycycline, Zinc and Vitamin D3 — as a preventive as well as treating method. Addressing a media conference in Kalaburagi on Monday, the senior doctor said that the use of Ivermectin would be more effective than that of Hydroxychloroquine which was widely being used worldwide, right from the outbreak of the pandemic. Referring to a pre-official release of a randomised controlled...

Thomas Borody MB,BS, BSc (Med), MD PhD, DSc, FRACP, FACP, FACG, AGAF, touts FDA and TGA approved Ivermectin, which he reports to use regularly in his hospital as it evidences positive results for COVID-19 and should be used immediately to fight the pandemic. The developer of the world’s first cure for peptic ulcers, which saved millions of lives worldwide, employed the same methodology to come up with the Ivermectin triple therapy. With over 30 formal clinical trials, many dozens of observational real-world initiatives and hundreds to possibly thousands of doctors already using the medicine, a particular momentum gains speed for...

Australian radio host Luke Bona interviewed this August 12 Professor Thomas Borody, from the Centre for Digestive Diseases in Sydney, Australia, about Ivermectin-based therapies for COVID-19.  The interview is short and to the point, and should be of interest to everyone in the world. Based on existing research and his analysis of therapeutic results using Ivermectin in combination with 2 other widely available generic drugs – Doxycycline and Zinc -, he asserts that COVID-19 is now curable and even easier to treat than the flu. Here are some excerpts. “We came up with a treatment that is simple, safe,...

 Report begins at 1:06.Starts at 1:47 actually.Doxycycline and Ivermectin.Antibiotic and antifungal,100% cure of 60 patients.1-4 cents per pill. https://youtu.be/bU_is2lHfVk  

A New York doctor hopes to help his elderly COVID-19 patients with a treatment plan inspired by the success tentatively being reported with hydroxychloroquine — and which he says shows promising results. Dr. Mohammud Alam, an infectious disease specialist affiliated with Plainview Hospital, said 81 percent of infected covid patients he treated at three Long Island nursing homes recovered from the contagion.

Abstract Here, we propose a new strategy for the treatment of early cancerous lesions and advanced metastatic disease, via the selective targeting of cancer stem cells (CSCs), a.k.a., tumor-initiating cells (TICs). We searched for a global phenotypic characteristic that was highly conserved among cancer stem cells, across multiple tumor types, to provide a mutation-independent approach to cancer therapy. This would allow us to target cancer stem cells, effectively treating cancer as a single disease of “stemness”, independently of the tumor tissue type. Using this approach, we identified a conserved phenotypic weak point – a strict dependence on mitochondrial biogenesis for...

Sagrario Ortega/Spanish National Cancer Research Center (CNIO), MadridPregnant with possibilities. Cells reprogrammed in living mice (green) can contribute to both the placenta and body tissues of a developing mouse. Cells Reprogrammed in Living Mice Researchers have discovered a surprisingly effective way to “reprogram” mature mouse cells into an embryolike state, able to become any of the body’s cell types. Their recipe: Let the transformation happen in a living animal instead of a petri dish. The finding could help scientists better understand how reprogramming works and it may one day help breed replacement tissues or organs in the lab—or in patients.In...

Reuters A drug-resistant "superbug" found in hospitals has a close cousin that is affecting athletes, prisoners and small children in growing numbers across the United States, disease experts said yesterday. Methicillin-resistant Staphylococcus aureus or MRSA can become fatal if not treated with the right antibiotics, said Daniel B. Jernigan of the Centers for Disease Control and Prevention. "MRSA is showing up in places it had never been seen before -- as a predominant cause of skin disease among children in some regions of the country, as clusters of abscesses among sports participants, as the most common cause of skin infections...