Now that Hillary Clinton has been confirmed as Secretary of State, the Obama administration will announce Thursday two high-profile appointments -- former senate majority leader George Mitchell (D-Me.) as Middle East envoy and former U.N. ambassador Richard Holbrooke as envoy for Afghanistan, Pakistan "and related matters," sources close to the administration said. Mitchell will be charged with rebuilding the Middle East peace process in the wake of the three weeks of violence between Israel and the Palestinian militant group Hamas. Holbrooke will take on the difficult job of soothing relations between Afghanistan and Pakistan, whose border is a haven for...