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Could this be the end of Alzheimer's ?
dailymail ^ | 8/31/16

Posted on 08/31/2016 1:25:29 PM PDT by Tilted Irish Kilt

A revolutionary drug that could stop people from ever developing Alzheimer’s disease has been unveiled by scientists.

Trials have produced ‘unprecedented’ results and the medicine has been hailed as a potential game-changer in the fight against the cruel disease.

In future, healthy pensioners could be prescribed the drug to ward off dementia, in much the same way as statins are given today to those at risk of heart attacks.

One British expert described the drug, which is about to be tested in hospitals around the UK, as the best yet, others called it ‘ingenious’ work with ‘tantalising’ results.And a US doctor hailed it as the best news in his 25-year career.

Existing drugs are of limited benefit and despite billions of pounds being spent on research, no new medicines have hit the market in more than a decade.

While current therapies ease the symptoms, aducanumab tackles the underlying damage in the brain, raising hopes it will be the first to alter the course of the disease.

(Excerpt) Read more at dailymail.co.uk ...


TOPICS: Health/Medicine; Science
KEYWORDS: alzheimers; alzheimerscure; biogen; dementia; dsj02; prevention; scc
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To: hawkaw

I forget.


81 posted on 08/31/2016 3:00:12 PM PDT by Jonty30 (What Islam and secularism have in common is that they are both death cults)
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To: Tilted Irish Kilt
Yes, I think that that drug is now in clinical trial here and the office where my wife receives treatment now has it - the name sounds familiar. Unfortunately there are a couple issues. The one she is currently on is a "mab" drug too (mitochondrial antibody) and when her trial ends in October unless she was on the placebo she cannot go onto that drug since that is also an mab drug. They (the pharmaceutical company) have a policy where she has to wait 48 weeks to go on another mab type drug. So unless the one she is on now opens the books to us to let us know if she is on placebo or was receiving the drug she has almost a year to wait just using aricept and namenda which are not very effective.

If this was showing progress and there was enough pressure like they had with AIDS they could shorten the trial period and get it into the public's hands under the compassionate use guidelines. It is a shame as I watch my wife drift further and further away and she just turned 60. Sometimes I just lay there in bed watching her sleep and I cry thinking about what lies ahead for her.

82 posted on 08/31/2016 3:00:32 PM PDT by Dad was my hero
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To: Tilted Irish Kilt

I hope it works better than “statins” against heart attacks as they have been essentially worthless in than regard.


83 posted on 08/31/2016 3:03:07 PM PDT by traderrob6
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To: Tilted Irish Kilt

Clinical trials seems to involve “mild to moderate Alzheimer’s Disease”.

It’s the serious Alzheimer’s disease that’s the serious problem.

My aunt forgetting to put out the garbage Monday wasn’t a big problem, the bin men got her can if she didn’t have it out.


84 posted on 08/31/2016 3:05:46 PM PDT by Brian Griffin
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To: Brian Griffin
Brian Griffin :
www.dddmag.com/news/2016/07/taurx-alzheimers-drug-fails-late-stage-trial?cmpid=horizontalcontent

A 15 % benefit to alzheimer's patients in not all that significant
unless you are one of those 15%
So the tau medication appears to not be successful, or not successful enough to pursue further testing.
Perhaps a combination of the two medications in synergy ?

85 posted on 08/31/2016 3:05:56 PM PDT by Tilted Irish Kilt ( British historian Arnold Toynbee - Civilisations die from suicide, not by murder.)
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To: BitWielder1
It seems there are always reports of medical "breakthroughs" on dread diseases popping up in the news..

And then we never hear about it again.

86 posted on 08/31/2016 3:11:58 PM PDT by daler
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To: safeasthebanks

If Mexico is smart,,,,,,,,Oldtimer’s tourism!


87 posted on 08/31/2016 3:17:02 PM PDT by Dr. Bogus Pachysandra (Don't touch that thing Don't let anybody touch that thing!I'm a Doctor and I won't touch that thing!)
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To: Tilted Irish Kilt

Perhaps it arrests the typical Alzheimer’s decline, once initiated as a preventative treatment. The amyloid kills neurons and causes permanent structural changes to the brain. It seems to act to stop any further damage occurring, without actually regenerating brain tissue.

Stroke patients can regain function by the retraining of healthy portions of the brain to perform the functions of areas which became injured. Perhaps the losses to Alzheimer can be compensated for in an analogous fashion.


88 posted on 08/31/2016 3:20:25 PM PDT by Ozark Tom (The binding rules only allow hints to be given freely in lieu of actual disclosures.)
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To: pepsi_junkie

Not funny to people who have relatives with either


89 posted on 08/31/2016 3:32:08 PM PDT by uncbob
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To: Ozark Tom
Ozark Tom :" Perhaps it arrests the typical Alzheimer’s decline, once initiated as a preventative treatment"

Yes , this was mentioned as a possible use for prevention in the original news source article.
The key question is whether the build up of amaloyoid proteins was the cause , or a symptom of the disease.
Further studies , and Class studies will be needed involving larger numbers of participants to demonstrate effectiveness.

90 posted on 08/31/2016 3:37:14 PM PDT by Tilted Irish Kilt ( British historian Arnold Toynbee - Civilisations die from suicide, not by murder.)
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To: Tilted Irish Kilt

Wonderful news!


91 posted on 08/31/2016 3:43:38 PM PDT by Bigg Red (Go away, Satan! -- Fr.Jacques Hamel (R.I.P., martyr))
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To: Tilted Irish Kilt

I’m interested in seeing how they get this drug past the blood-brain barrier.

Great post!


92 posted on 08/31/2016 3:46:03 PM PDT by <1/1,000,000th%
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To: napscoordinator

“Diabetes is another place where a cure will never happen”

There is already a cure for type 2 diabetes. I know from personal experience. They had to take me off my diabetes meds because my glucose was going to low. A1C has been at 5.5 for a year now...


93 posted on 08/31/2016 3:50:10 PM PDT by babygene (Make America Great Again)
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To: Buttons12
Bamunacuda has a better flow to it.

Does it have a HEMI in it though?

94 posted on 08/31/2016 4:02:59 PM PDT by Blue Highway
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To: hawkaw

No, do not put your faith in magic drugs. All drugs have bad consequences.

Look at yourself in the mirror. Now take charge of your health. Adjust your habits.

All the people I know dying off early or painfully did not take charge of their health. The best investment is small changes in one’s behavior.


95 posted on 08/31/2016 4:10:30 PM PDT by TheNext (Hillary Hurts Children & Women)
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To: Tilted Irish Kilt

Importantly, for years dentists noted a strong correlation between chronic gum disease and Alzheimer’s. It was established that gum disease allows the five spirochete bacteria that commonly dwell in the mouth to slip past the blood/brain barrier and enter the brain.

While they do not cause an infection there, when they die, the remnants of a vast number of bacteria seem to form the plaque associated with Alzheimer’s.

The solution to this is easy. While ordinary toothpaste is good at reducing plaque and tartar, as well as strengthening the teeth, ordinary powdered baking soda is particularly lethal to spirochete bacteria, killing them with just five seconds of exposure.

Baking soda toothpaste is not concentrated enough to do this, however. So they now advise to *alternate* brushing the teeth with toothpaste and powdered baking soda on different days. This may prevent Alzheimer’s in the first place.


96 posted on 08/31/2016 4:14:49 PM PDT by yefragetuwrabrumuy ("Don't compare me to the almighty, compare me to the alternative." -Obama, 09-24-11)
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To: yefragetuwrabrumuy
yefragetuwrabrumuy :" ordinary powdered baking soda is particularly lethal to spirochete bacteria, killing them with just five seconds of exposure."

Which goes to show you that the 'old ways' weren't quite so dumb as many people believe.
I had also heard that people who lost teeth early in life, or in mid-life, also had a lower incidence of Alzheimer's.
So that may lead credence to what you have stated regarding spirochetes in the mouth .

97 posted on 08/31/2016 4:31:54 PM PDT by Tilted Irish Kilt ( British historian Arnold Toynbee - Civilisations die from suicide, not by murder.)
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To: yefragetuwrabrumuy
yefragetuwrabrumuy :" ordinary powdered baking soda is particularly lethal to spirochete bacteria, killing them with just five seconds of exposure."

As I recall, 'old timey' toothpaste consisted of baking soda and pumice.
Unfortunately, pumice wears down the enamel of the teeth, while the baking soda cleanses the teeth.
Frequent brushing of teeth resulted in tooth loss.

98 posted on 08/31/2016 4:35:52 PM PDT by Tilted Irish Kilt ( British historian Arnold Toynbee - Civilisations die from suicide, not by murder.)
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To: TheNext

I started when I was 33 by stopping the cigs. In my 50s now, I run 1/2 marathons and eat much better. Yes, I fully support your suggestions and try my best to follow through on them.


99 posted on 08/31/2016 4:37:09 PM PDT by hawkaw
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To: Tilted Irish Kilt

.
All I know is that there is not a shred of evidence for causation by the plaque.

Even correlation is iffy. There are so many cases of similar effects without the plaque. (Mother-in-law being one, showing the same effects for 16 years without a trace of the assumed causes)


100 posted on 08/31/2016 4:40:00 PM PDT by editor-surveyor (Freepers: Not as smart as I'd hoped they'd be)
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