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How aspirin stops the growth and spread of colorectal cancer
New Atlas ^ | April 23, 2024 | Bronwyn Thompson

Posted on 04/23/2024 11:37:08 AM PDT by Red Badger

Around 29 million people in the US take a daily dose of aspirin as a preventative measure for cardiovascular disease. And while an age-related increased risk of bleeding has seen it fall out of favor with medical authorities, it's now shaping up as something that might be even more beneficial in triggering the immune system to help take down certain cancers.

There's been a growing body of research showing that regular, long-term low-dose aspirin use was associated with better outcomes of colorectal cancer (CRC). But scientists haven't been entirely sure just why the common over-the-counter medicine was having a distinctive and seemingly targeted effect on the growth and spread of CRC, and gathering long-term data on this area of aspirin use has been challenging.

That earlier Harvard-led study found that a regular aspirin regimen could prevent almost 11% of colorectal cancers and 8% of gastrointestinal cancers diagnosed in the US every year. Now, Italian researchers have looked at clinical and pathological records of all CRC patients operated on at Chirurgia Generale Unit in Padova, Italy, from 2015 to 2019. Of these 238 patients, 31 (13%) were considered aspirin users – those who took 100 mg of the nonsteroidal anti-inflammatory drug per day.

These 238 patients – known as the METACCRE cohort – underwent histology analysis, with scientists looking at tumor-infiltrating lymphocytes (TIL), immunochemistry and mutation data. A subset of patients slotted into the IMMUNOREACT1 cohort, that specifically focused on immunohistochemistry and flow cytometry.

In simpler terms, what the scientists found was that regular aspirin use appeared to limit nodal metastasis (cancer spread) and produced a higher number of tumor-infiltrating lymphocytes – the T and B cells that can recognize cancer cells and kill them.

(Excerpt) Read more at newatlas.com ...


TOPICS: Business/Economy; Food; Health/Medicine; Society
KEYWORDS: aspirin; coloncancer; tcoyh
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To: woodbutcher1963

Willow Tree Bark.

Who would have thunk it?


https://www.mcgill.ca/oss/article/medical-history/forget-willow-bark-extract-go-aspirin


21 posted on 04/23/2024 7:17:45 PM PDT by Jane Long (The role of the GOP: to write sharply-worded letters as America becomes a communist hell-hole.)
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To: Jane Long

Willow Tree Bark.


Tastes like wild hickory nuts.


22 posted on 04/23/2024 7:18:19 PM PDT by dfwgator (Endut! Hoch Hech!)
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To: dfwgator

:-)

Interesting.

I’d have no idea. Never tried it.


23 posted on 04/23/2024 7:19:12 PM PDT by Jane Long (The role of the GOP: to write sharply-worded letters as America becomes a communist hell-hole.)
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To: dfwgator

Tastes like wild hickory nuts.


But ..... I bet you and Euell sure would know.

πŸ˜‚


24 posted on 04/23/2024 7:20:37 PM PDT by Jane Long (The role of the GOP: to write sharply-worded letters as America becomes a communist hell-hole.)
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To: Myrddin

Good luck to you and God bless.


25 posted on 04/23/2024 7:39:32 PM PDT by Veto! (FJB Sucks Rocks)
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To: dfwgator
Now that's a reference I haven't heard in a long time ... long time.
26 posted on 04/23/2024 7:54:24 PM PDT by Tellurian (Any cleverness from a democrat is quickly invested in deception)
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To: Veto!
Thanks. This was not the rabbit hole I expected to follow this year.
27 posted on 04/23/2024 8:04:52 PM PDT by Myrddin
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To: Myrddin; ConservativeMind; Dr. Sivana; Red Badger; little jeremiah; Tilted Irish Kilt; ...

I wonder how much Vitamin C and E you are taking as both are important for wound healing and tissue formation. Fifty years ago around the time I was having children, I suffered from chronic anemia. THe doctor prescribed taking Iron (Feosole?) which did not help much. Then I started taking Vitamin E for my post partum developing varicose veins and Vitamin C for my allergies. My RBC level soon returned to normal and I then ran across a study saying that Vitamin E could make the difference of only an 85 day life span for RBCs, versus 110 days life span for RBCs with the E. And my varicose veins shrank and disappeared.

Dr. Robert Cathcart has written a lot of interesting material on therapeutic use of Vitamin C for many serious illnesses and conditions. An interesting study in TUrkey in 2021 showed that the Dr. Zelenko Covid protocol for Covid using zinc, HCQ, and Azithromycin (Zelenko later preferred Doxycycline) was effective Covid treatment, but adding some days of 25 gram IV Vitamin C shortened hospital stays by 3 weeks. TAKE THAT, Remdesivir! The only death in this study of nearly 250 older hospitalized patients, many with comorbidities had only ONE death. This elderly woman, I think with cancer, was acutely deficient in Vitamin D.

Aside from interest in Zinc I gained from learning about Dr. Zelenko’s work, I began reading a number of studies as I had three loved ones in fall 2022 all dealing with cancer, including prostate, and colon with metastatic liver cancer. One study from late spring 2020 found that the two cancers I just mentioned plus 7 other common cancers all had zinc defficient cancerous tissue even when surrounding healthy tissue was well supplied with zinc. These doctors were enthusiastic about the idea of giving more zince, and even using some form of ionophore to help the zinc get into cancer cells. Some ionophores we have heard of include HCQ, Ivermectin, Quercetin, HGCG (green tea), and Resveritrol. There are others as well. The summer of 2020 I tried at least 6 times to write in AOL comments at their articles explaining the possibility of zinc and an ionophore helping save Covid patients lives and health. I was censored on each of these occasions for violating “community standards” with my polite science based words. No such censorship for all the nasty things said about Trump or Biden in the comments for these same articles.

Therefore I was not surprised to see that a few months after late Spring 2020, in further writings, these scientists were a lot more subdued in their enthusiasm for ZINC as a miracle find for possible cancer treatment. However I enthusiastically added this to supplements I was providing to the two people who were still actively treating their cancers, the third person was finished with apparently successful treatment for the moment. Another study indicated that Astaxanthin, which I was already taking successfully for my cataracts, apparently increased apoptosis (natural death) of cancer cells while providing longer life for normal cells. So I added that to their supplements.

The prostate cancer now seems to be completely stopped for the past year. Unfortunately my brother whose liver cancer was improving nicely, took his 4th Covid shot before I could tell him about the IgG4 class switch I had just learned about. Two weeks later he was on a rapid slide toward death.


28 posted on 04/24/2024 2:34:53 AM PDT by gleeaikin ( Question authority.)
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To: gleeaikin
I haven't been as faithful in my consumption of vitamin A and E over the last few years. 2g of vitamin C daily. 50 mg of zinc daily with quercetin. 10000IU D3 + 500 mcg K2 daily. I could improve my vitamin E input and compare the impact on my next CBC. I'm concerned that after the Whipple rearrangement of my gut, I'll have a challenge keeping my fat soluble vitamin levels up. I'm going to have to supplement with ox bile and pancreatic enzymes to compensate for excised capability. Whipple recovery is no picnic.
29 posted on 04/24/2024 7:48:08 AM PDT by Myrddin
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To: Red Badger

Excellent book, and he confirms what I know as a defense attorney - doctors cannot go outside the “standard of care” which ends up precluding all innovations and creative care. The risk their licenses and certainly their malpractice insurance if they do so. They can also lose their licenses for prescribing medications for reasons other than those approved by the FDA and the prevailing “standard of care.”


30 posted on 04/24/2024 7:59:13 AM PDT by esquirette ("Our hearts are restless until they find rest in Thee." ~ Augustine)
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To: gleeaikin
Sorry to hear about your brother; my condolences.

Thanks for all of the other interesting info.

31 posted on 04/24/2024 12:19:34 PM PDT by chud
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To: Myrddin

I’ve had a suspicion that the Whipple procedure is what Kate Middleton had done to her in January. It is a long recovery. I also think she has a history of Crohn’s disease.

Speedy recovery to you !


32 posted on 04/25/2024 4:06:52 AM PDT by Baldwin77 (DJ & JD 2024 (Trump-Vance) NOVEMBER 5-CHRISTIAN VISIBILITY DAY)
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To: Baldwin77
Thanks. I have a high school classmate who has been fighting pancreatic cancer. He has endured a year of chemo and radiation to reach a point where a Whipple would be attempted. He had the Whipple 4 months ago. After the Whipple, it was determined to not be a 100% fix for my classmate, BUT...the antigen tracking of CA 19-9 and CEA show a huge improvement for him. Perhaps a 2 year horizon for him now. As of April 11th, I'm on the path to a Whipple myself. I linked up my local "myChart" to the one at University of Utah/Huntsman Cancer Center this morning. First consult will be May 16th with the surgeon. The 3 week wait means the cancer has time to grow and spread. The last time I had a cancer diagnosis in 1985, I had the surgery to remove it the next morning. This one is orders of magnitude more complex to perform.
33 posted on 04/25/2024 7:49:26 AM PDT by Myrddin
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To: Myrddin; chud

Please make a point of reading up on Dr. Robert Cathcart’s Vitamin C experiences. He recommends that even completely healthy people should consume 4 grams of C per day, about 1 gram every 6 hours. Amounts he has successfully used for severe illnesses, have been as much as 100 to 200 grams IV over 24 hours.


34 posted on 04/26/2024 12:53:36 AM PDT by gleeaikin ( Question authority.)
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To: gleeaikin
I've consumed 2 grams daily for the last 30 years. Having lost my gallbladder last month, I now need to carefully consume my fat soluble (A, E, D3, K2) vitamins to pair with fatty food and ox bile to ensure that I can absorb them. I'm adding a heme based iron supplement that needs to be taken apart from calcium and turmeric to get ahead of the anemia. B12 needs to be separate from vitamin C. Post Whipple procedure, it will become more complex. It's manageable complexity, just not welcome with all the other things in play.
35 posted on 04/26/2024 7:45:21 AM PDT by Myrddin
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To: Myrddin; All

https://www.canceractive.com/article/antiworm-drug%20for%20animals%20effective%20at%20killing%20cancer%20cells


36 posted on 04/27/2024 2:59:11 AM PDT by Ancesthntr (β€œThe right to buy weapons is the right to be free.” ― A.E. Van Vogt, The Weapons Shops of Isher)
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