Posted on 03/30/2010 3:21:27 PM PDT by decimon
BIRMINGHAM, Ala. - The age-old maxim "Eat breakfast like a king, lunch like a prince and dinner like a pauper" may in fact be the best advice to follow to prevent metabolic syndrome, according to a new University of Alabama at Birmingham (UAB) study.
Metabolic syndrome is characterized by abdominal obesity, high triglycerides, insulin resistance and other cardiovascular disease-risk factors.
The study, published online March 30 in the International Journal of Obesity, examined the influence exerted by the type of foods and specific timing of intake on the development of metabolic syndrome characteristics in mice. The UAB research revealed that mice fed a meal higher in fat after waking had normal metabolic profiles. In contrast, mice that ate a more carbohydrate-rich diet in the morning and consumed a high-fat meal at the end of the day saw increased weight gain, adiposity, glucose intolerance and other markers of the metabolic syndrome.
"Studies have looked at the type and quantity of food intake, but nobody has undertaken the question of whether the timing of what you eat and when you eat it influences body weight, even though we know sleep and altered circadian rhythms influence body weight," said the study's lead author Molly Bray, Ph.D., professor of epidemiology in the UAB School of Public Health.
Bray said the research team found that fat intake at the time of waking seems to turn on fat metabolism very efficiently and also turns on the animal's ability to respond to different types of food later in the day. When the animals were fed carbohydrates upon waking, carbohydrate metabolism was turned on and seemed to stay on even when the animal was eating different kinds of food later in the day.
"The first meal you have appears to program your metabolism for the rest of the day," said study senior author Martin Young, Ph.D., associate professor of medicine in the UAB Division of Cardiovascular Disease. "This study suggests that if you ate a carbohydrate-rich breakfast it would promote carbohydrate utilization throughout the rest of the day, whereas, if you have a fat-rich breakfast, you have metabolic plasticity to transfer your energy utilization between carbohydrate and fat."
Bray and Young said the implications of this research are important for human dietary recommendations. Humans rarely eat a uniform diet throughout the day and need the ability to respond to alterations in diet quality. Adjusting dietary composition of a given meal is an important component in energy balance, and they said their findings suggest that recommendations for weight reduction and/or maintenance should include information about the timing of dietary intake plus the quality and quantity of intake.
"Humans eat a mixed diet, and our study, which we have repeated four times in animals, seems to show that if you really want to be able to efficiently respond to mixed meals across a day then a meal in higher fat content in the morning is a good thing," Bray said. "Another important component of our study is that, at the end of the day, the mice ate a low-caloric density meal, and we think that combination is key to the health benefits we've seen."
Bray and Young said further research needs to test whether similar observations are made with different types of dietary fats and carbohydrates, and it needs to be tested in humans to see if the findings are similar between rodents and humans.
"We're also working on a study right now to determine if these feeding regimens adversely affect heart function," Young said.
About the UAB School of Public Health
The UAB School of Public Health is a community of scholars and professionals working and teaching in varied arenas of public health with the goal of fostering research and best practices crucial to the health of the United States and its peoples. The school offers more than 20 areas of study and manages dozens of research and community-service centers.
About the UAB Division of Cardiovascular Disease
The UAB Division of Cardiovascular Disease emphasizes excellence in patient care, teaching plus basic and clinical research. Clinical research is closely associated with individual clinical cardiology services and encompasses a variety of opportunities and interactions with faculty associated with numerous large federal- and industry-supported clinical trials. Media Contact
Media Contact: Jennifer Lollar (205) 934-3888 jpark@uab.edu
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Posted by Andrea Reiber on 3/30/2010 1:55:00 PM
Odd thing - I don't see Andrea Reiber's name in the original though it appears in this copy.
Consider the source.
Don’t tell Glenn Reynolds ping.
Whatchoo got agin 'Bama?
Boy, they ain’t ‘nuff bacon on that hole muffin.
Not kosher. Double plus not kosher on Passover,
ping
All I can say is “DUH”.
Any kind of dry cereal and milk do nothing for me except to give me a migrane.
A little leftover pasta, leftover cheese souffle, chili and beans, etc..............keep me going all day.
You knew, of course, that additional research is needed. That phrase (or variations thereon) sneaks its way into every scientific study notice.
What’s your problem with the source, Mac?
Its such a cop-out. I say the end of a paper should have a statement like "That's the deal man, prove me wrong." Or something similarly provocative.
It’s missing the mayo and cheese.
My old man couldn’t eat a donut without first spreading butter on it. Yikes.
ping for later read
“Having lived in the Great State of Alabama where the fry Pickles, Ice Cream and Snickers bars, please do not trust this article!”
It’s certainly true that if this study were sponsored by the Hog Farmers of America, there might be some reason to doubt its veracity.
I like that approach. I guess I am not nuanced enough. I too like declarative sentences, unlike the stuff that comes out of the scientific community.
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