Posted on 09/04/2011 5:33:09 PM PDT by decimon
(Edmonton) Researchers in the Faculty of Medicine & Dentistry at the University of Alberta have discovered that resveratrol, a powerful antioxidant found in common foods, prevents a syndrome in some offspring that could lead to later health issues such as diabetes.
Resveratrol is found in fruits, nuts and red wine, and has been shown to extend the lifespan of many species.
Human offspring that have trouble growing in the womb have an increased risk of developing metabolic problems later in life. But U of A medical researchers Jason Dyck and Sandra Davidge and their teams found that administering resveratrol to the young offspring of lab rats after weaning actually prevented the development of a metabolic syndrome, which is characterized by glucose intolerance, insulin resistance and higher deposits of abdominal fat.
Dyck and Davidge published their findings in a recent edition of the peer-reviewed journal Diabetes. Dyck is a researcher in the departments of Pediatrics and Pharmacology, while Davidge is a researcher in the departments of Obstetrics & Gynecology and Physiology. Both are also members of the Mazankowski Alberta Heart Institute, as well as the Women and Children’s Health Research Institute. Dyck and Davidge were co-senior authors of the study.
The study took advantage of the fact that "infancy is a potential window of opportunity to intervene and prevent the future development of metabolic diseases." The researchers noted this is the first potential pharmacological treatment that may help babies that developed in a growth-restricted environment in the womb.
"There is a concept that in utero, there are genetic shifts that are occurring – reprogramming is occurring because of this strenuous environment babies are in, that allows them to recover very quickly after birth," says Dyck.
"When babies are growth-restricted, they usually have a catch-up period after they are born where they catch up to non-growth-restricted groups. It might be that reprogramming that creates this kind of 'thrifty' phenotype, where they want to consume and store and get caught up.
"That reprogramming appears to make them more vulnerable to developing a host of metabolic problems."
Earlier this year, Dyck and Davidge published another paper in Diabetes demonstrating that rat offspring not growing well in the womb had noticeable side effects from high-fat diets after birth – the rats deposited more fat in the abdominal area, developed glucose intolerance, more dramatic cases of insulin resistance and insulin resistance at earlier stages of life.
Dyck and Davidge are continuing their research in this area, examining whether treating the mother during pregnancy can prevent metabolic problems in rat offspring affected by intrauterine growth restriction.
Davidge is an Alberta Innovates-Health Solutions (AIHS) Scientist and a Canada Research Chair in Women’s Cardiovascular Health. Dyck is an AIHS Senior Scholar and the Director of the Cardiovascular Research Centre at the U of A.
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Their research was funded by: the Canadian Institutes of Health Research, the Heart & Stroke Foundation of Canada, and the Women and Children’s Health Research Institute.
You obviously have more than a casual interest in that product.
Resveratrol is a very good antioxidant, among other things. It is derived from either Japanese Knotweed or from Mascadine GrapesThe type derived from grapes has better activity, especially when combined with the skins of the grape. Dosages should be 400-600 mg. Of trans-resveratrol, which is standardized from resveratrol. NutraBio.com has the best product for the price and does not contain fillers. You can get bulk pricing. For all who need help, metabolic syndrome is most likely caused from glycation, which is caused by too many carbohydrates coupled with a toxicity to environmental toxins of other chemicals put into refined, packaged food. Systemic Enzymes help to limit glycation. Also, cinnamon is another good spice to use on a daily basis. Hope everyone finds this useful.
Just tiny amounts are in wine.
It’s pretty pricey about anywhere.
What do you do now?
That can only mean one thing.....
A local doctor had me try Byetta a couple of years ago. The meds made me sick and tired, but the doctor said it would pass in about 3 weeks and start working. But after 4-5 weeks of being sick and tired, I got sick and tired of being sick and tired so I stopped using it.
So I haven't done anything for about 2 years. It's interesting; I've been going over some medical records from about 3-4 years ago, and the results of a scan came back showing the possibility of a growth on my thyroid gland. If memory serves, the thyroid gland is what regulates the body's metabolism. I wonder if there is a connection. I saw this article online one day and I wonder if I have the same thing Nolin has:
Gena Lee Nolin - Thyroid Illness
I'd like to have that checked out again, but in the meantime I'll check out what was posted here in this thread and see what happens. Thanks all for your suggestions.
You should completely eliminate sugar from your diet as the first basic step.
Another suggestion with regards to your thyroid issue. An overgrowth of Candida Albicans can cause thyroid disorders. However, typical thyroid tests will not indicate this. You must have a Candida antibody test. The pitfall is only 1 out of 6 physicians have the necessary knowledge about Candida and how it effects our entire body and organ systems. Many people who have metabolic syndrome will show a high antibody level and high, whats called RT3(reverse T3) numbers. Candida is silent and does not always present itself as skin erruptions or nail fungus. Lastly, bromide toxicity plays a large role in thyroid disfunction as it competes for Iodine, for the lone receptor site. Many baked goods use brominated flour. It is in plastics, fire retardents,computer keyboards and screens, clothing, soda and other textiles. Unfortunately, some people have a lower tolerance to this. The good news is that diet and proper supplementation can reverse anything, if it is implemented soon enough and there is a willingness to follow through. Good luck!
Exp Biol Med (Maywood). 2004 Jun;229(6):473-8.
Iodine toxicity and its amelioration.
Baker DH.
Department of Animal Sciences and Division of Nutritional Sciences,
290 Animal Sciences Laboratory,
University of Illinois
I think I'm gonna change doctors and see what happens. I need to have everything all checked out, again, and see what the docs say. Resveratrol is an interesting item to check out and I will next time I'm near a CVS (thanks decimon).
In the meantime, we'll see what happens. Thanks again for everything.
As for Thyroid activity not being changed, it is not the immediate concern. The study states it “can”. That is not definitive.
The function of the Thymus gland is what gets affected first, along with adrenal function and metabolism of fats. Also, Bromine makes Iodine become like water to the body, and it just flushes it out. It also can cause “False” Thyroid tests that show normal limits. Long term toxicity, will then begin to cause disruption in function. Thyroid function is dependent on the Thymus gland. Lastly, Thyroid blood tests are one of the most inaccurate of medical tests.
It could be one of the reasons Thyroid disfunction is on the rise, due to the replacement of Iodine with Bromine in the flour industry over the last 50-60 years.
You can research more at drmercola.com and google search dr.brownstein and bromide toxicity. You can come to your own truthful conclusions. In my practice, this is what I see on a weekly basis.
Almost forgot! You can check out “The Bromide Dominance Theory.” Just google it.
You are WELCOME! NutraBio.com best for Resveratrol. Take care!
As for Thyroid activity not being changed, it is not the immediate concern. The study states it “can”. That is not definitive.
The function of the Thymus gland is what gets affected first, along with adrenal function and metabolism of fats. Also, Bromine makes Iodine become like water to the body, and it just flushes it out. It also can cause “False” Thyroid tests that show normal limits. Long term toxicity, will then begin to cause disruption in function. Thyroid function is dependent on the Thymus gland. Lastly, Thyroid blood tests are one of the most inaccurate of medical tests.
It could be one of the reasons Thyroid disfunction is on the rise, due to the replacement of Iodine with Bromine in the flour industry over the last 50-60 years.
You can research more at drmercola.com and google search dr.brownstein and bromide toxicity. You can come to your own truthful conclusions. In my practice, this is what I see on a weekly basis.
You are a medical doctor?
I am a Certified Personal Trainer, Nutritional Specialist and will be getting my Doctor of Naturopathy license this year. I am also a product formulator. I have been engaged in the science and art of healing for the last 20 years. Most important, I am driven by helping people get fit, healthy and live longer and more productive lives.
You’re singin’ my song! I am just now getting around to reading the resveratrol thread and see that you’re proficient in iodine :)
I posted this thread the other night
http://www.freerepublic.com/focus/f-chat/2775065/posts?page=1
I’m working on getting my thyroid under control. I’m on 50mg iodoral, salt, mag, Vit C, B complex. All in all feeling really well. I am having difficulty getting my sugar under control and was reading up on taking higher doses of chromium picolonate.
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