Posted on 09/01/2013 2:06:31 PM PDT by Dysart
A number of intestinal pathogens can cause problems after antibiotic administration, said Justin Sonnenburg, PhD, assistant professor of microbiology and immunology and the senior author of the study, to be published online Sept. 1 in Nature. Graduate students Katharine Ng and Jessica Ferreyra shared lead authorship.
"Antibiotics open the door for these pathogens to take hold. But how, exactly, that occurs hasn't been well understood," Sonnenburg said. In the first 24 hours after administration of oral antibiotics, a spike in carbohydrate availability takes place in the gut, the study says. This transient nutrient surplus, combined with the reduction of friendly gut-dwelling bacteria due to antibiotics, permits at least two potentially deadly pathogens to get a toehold in that otherwise more forbidding environment.
In the past decade or so, much has been learned about the complex microbial ecosystem that resides in every healthy mammal's large intestine, including ours. The thousands of distinct bacterial strains that normally inhabit this challenging but nutrient-rich niche have adapted to it so well that we have difficulty living without them. They manufacture vitamins, provide critical training to our immune systems and even guide the development of our own tissues. Antibiotics decimate this gut-microbe ecosystem, which begins bouncing back within a few days but may take a month or more to regain its former numbers. And the ecosystem appears to suffer the permanent loss of some of its constituent bacterial strains.
It is thought that our commensal, or friendly, bacteria serve as a kind of lawn that, in commandeering the rich fertilizer that courses through our gut, outcompetes the less-well-behaved pathogenic "weeds." It has also been suggested that our commensal bugs secrete pathogen-killing factors. Another theory holds that the disruption of our inner microbial ecosystem somehow impairs our immune responsiveness.
(Excerpt) Read more at sciencedaily.com ...
Hi Dy,
I believe the ultimate probiotic is VSL #3 it is described:
VSL#3 high-potency probiotic medical food contains 8 different strains of live lactic acid bacteria that were specially selected to produce an optimal synergistic composition of bacteria. The 8 strains are:
Bifidobacterium breve
Bifidobacterium longum
Bifidobacterium infantis
Lactobacillus acidophilus
Lactobacillus plantarum
Lactobacillus paracasei
Lactobacillus bulgaricus
Streptococcus thermophilus
VSL#3 is a potent probiotic medical food that delivers the highest available concentration of beneficial live bacteria of any probiotic in the world
There are four formulations of VSL#3:
1. Capsules that contain 112.5 billion live bacteria
2. NEW - VSL#3 JUNIOR packets that contain 225 billion live bacteria
3. Packets that contain 450 billion live bacteria
4. Double Strength (DS) packets that contain 900 billion live bacteria. Due to the potency of this formulation, VSL#3 DS is a prescription only
medical food.
All except the last can be purchased without a prescription.
I have used it for several years and nothing has come close.
And I can pick it up from our local Walgreens.
PS NOT CHEAP, but good.
Regards,
Lurking’
Do not start any antibiotic.
They only weaken your immune system, making recovery less likely. They are at best only minimally effective at killing the infecting organism, but very effective at crippling your digestion and immune system.
>> “ Tooth feels fine now and I’m tempted to give the AB a rest.” <<
.
Shaky!
Once the antibiotic is started, stopping early stands some chance of resulting in an AB resistant infection that can be spread to others.
Too late for the best choice: not taking any AB ever.
Cool. Sounds like a nuclear option to restore proper gut critters. Billions upon billions!
>> “ Odd that it is milky in nature and probably not desirable” <<
.
Why would milk not be desirable?
The only milk that is not desirable is that which has had fat removed.
GT Dave's Kombucha Tea has S. Boulardi. Shake gently and drink.
If I understand correctly, most probiotics don't survive the stomach, and Keifer does. Lifeway Keifer is available inexpensively at Aldi, at least at my local store. Vinegar has acetobacter. Not certain if this falls in the probiotic category. Sauerkraut is supposed to have good bacteria as well.
I am reminded of when my son threw up after we fed him milk.
Augmentin caused me 10 months of gastro issues. I will NEVER take that garbage again. Activia doesn’t begin to touch what this stuff does to you.
i think some thought it was worthless because they assumed all the probiotics you were taking were just going to die. that isn’t the case that or maybe they figured people on them for a real short time didn’t experience enough negative results without probiotics it became practice to not give proobiotics altogether.
Bizzare!
You are not normal.
Thats, the stomach, then 20 feet of small intestine. A long way to travel.
How does it reach the large intestine in the first place? After all, we are probably not born with it.
Are probiotics carried along with food? Having it grow in the small intestine might not be good.
Lol. My wife would agree.
I had some serious dental surgery a few years ago,,,too massive doses of antibiotics..and since developed the leaky gut syndrome..a Candida overgrowth....and Chronic Fatigue.
Very high potency Probiotics are a part of my daily regime at the point.
I use UltraFlora™ Acute Care
A 3:1 blend of: 4 billion live organisms
Bifidobacterium lactis HN019
Lactobacillus rhamnosus<
Saccharomyces boulardii
providing 5.5 billion live organisms
“”Having it grow in the small intestine might not be good.”
the bad bacterium are unusually hardy , thus the need for massive doses of the Probiotics..and I’ve not heard of probiotics every being problematic.
you can bet the FDA would have laid done the law... if there were ever any reported problems encountered using probiotics
“”Having it grow in the small intestine might not be good.”
the bad bacterium are unusually hardy , thus the need for massive doses of the Probiotics..and I’ve not heard of probiotics every being problematic.
you can bet the FDA would have laid done the law... if there were ever any reported problems encountered using probiotics
or bop a charging dog with
450 billion
You need to do the math.
How many gallons of kefir would that be???
I’m surprised no one has mentioned fecal transplant therapy:
The length of a course of antibiotic must be studied and tested for years before FDA approval. If you stop a course of antibiotic too soon, you take the chance that the infection will come back worse than before. If the antibiotic is working for you, it is normal to experience symptom relief before the end of the prescribed course; but you should take every dose prescribed. Patient "noncompliance" is one of the leading causes of cost and waste in medical care.
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