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Professor Didier Raoult Releases the Results of a New Hydroxychloroquine Treatment Study on 1061 Patients
CovidExit.com ^ | 04/10/2020

Posted on 04/10/2020 6:05:33 PM PDT by SeekAndFind

The new study, of which the abstract was released today, was performed at IHU Méditerranée Infection, Marseille, France. A cohort of 1061 COVID-19 patients, treated for at least 3 days with the Hydroxychloroquine-Azithromycin (HCQ-AZ) combination and a follow-up of at least 9 days was investigated.

Key findings are:

A poor outcome was observed for 46 patients (4.3%); 10 were transferred to intensive care units, 5 patients died (0.47%) (74-95 years old) and 31 required 10 days of hospitalization or more.

The authors conclude that:

“The HCQ-AZ combination, when started immediately after diagnosis, is a safe and efficient treatment for COVID-19, with a mortality rate of 0.5%, in elderly patients. It avoids worsening and clears virus persistence and contagiosity in most cases.”

See the complete abstract below.

The original abstract can be accessed here.

Also, the researchers made this table available.

It’s not clear when the complete study will be made available.

ABSTRACT

Background

In a recent survey, most physicians worldwide considered that hydroxychloroquine (HCQ) and azithromycin (AZ) are the two most effective drugs among available molecules against COVID-19. Nevertheless, to date, one preliminary clinical trial only has demonstrated its efficacy on the viral load. Additionally, a clinical study including 80 patients was published, and in vitro efficiency of this association was demonstrated.

The study was performed at IHU Méditerranée Infection, Marseille, France. A cohort of 1061 COVID-19 patients, treated for at least 3 days with the HCQ-AZ combination and a follow-up of at least 9 days was investigated. Endpoints were death, worsening and viral shedding persistence.

Findings

From March 3rd to April 9th, 2020, 59,655 specimens from 38,617 patients were tested for COVID-19 by PCR. Of the 3,165 positive patients placed in the care of our institute, 1061 previously unpublished patients met our inclusion criteria. Their mean age was 43.6 years old and 492 were male (46.4%). No cardiac toxicity was observed. A good clinical outcome and virological cure was obtained in 973 patients within 10 days (91.7%). Prolonged viral carriage at completion of treatment was observed in 47 patients (4.4%) and was associated to a higher viral load at diagnosis (p < 10-2) but viral culture was negative at day 10 and all but one were PCR-cleared at day 15. A poor outcome was observed for 46 patients (4.3%); 10 were transferred to intensive care units, 5 patients died (0.47%) (74-95 years old) and 31 required 10 days of hospitalization or more. Among this group, 25 patients are now cured and 16 are still hospitalized (98% of patients cured so far). Poor clinical outcome was significantly associated to older age (OR 1.11), initial higher severity (OR 10.05) and low hydroxychloroquine serum concentration. In addition, both poor clinical and virological outcomes were associated to the use of selective beta-blocking agents and angiotensin II receptor blockers (P<0.05). Mortality was significantly lower in patients who had received > 3 days of HCQ-AZ than in patients treated with other regimens both at IHU and in all Marseille public hospitals (p< 10-2).

The HCQ-AZ combination, when started immediately after diagnosis, is a safe and efficient treatment for COVID-19, with a mortality rate of 0.5%, in elderly patients. It avoids worsening and clears virus persistence and contagiosity in most cases.


TOPICS: Health/Medicine; Science; Society
KEYWORDS: covid19; didierraoult; france; hcqzpac; hcqzpacstudy; hydroxychloroquine; raoult
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1 posted on 04/10/2020 6:05:33 PM PDT by SeekAndFind
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To: SeekAndFind
Now we may be getting somewhere. This will be hard to disregard.
2 posted on 04/10/2020 6:08:27 PM PDT by hinckley buzzard (Power is more often surrendered tha)
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To: SeekAndFind
ALSO SEE THIS:

Dr. Oz Explains A Breaking News Study Out Of France Today.



French doctor, Didier Raoult met with France’s Premier Emmanuel Macron last night to present a new paper that studied 1,061 COVID-19 patients that were treated early with hydroxchloroquine and azithromycin (z-pac). He found that those on this drug protocol met with nearly 92% excellent outcomes (they were free of the virus within 10 days). He also found the drug protocol to be very safe for patients with low side effects, and that there was a correlation with the amount of hydroxychloroquine found in the blood and success rates.

However, the paper also found that those patients who had high blood pressure and taking certain types of hypertension medications (beta blockers) had complications. This may lead to a clue that those with high blood pressure are more susceptible to COVID-19 or the medications they’re on can lead to more concerns.

CLICK ABOVE LINK FOR THE VIDEO


3 posted on 04/10/2020 6:09:16 PM PDT by SeekAndFind (look at Michigan, it will)
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To: SeekAndFind

to vaccine-adamant Fauci,
this means nothing. it is anecdotal.

NOTHING will stand in the way of Fauci-Gates-Soros
and their malicious plan infecting Earth.


4 posted on 04/10/2020 6:10:33 PM PDT by Diogenesis ( WWG1WGA)
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To: SeekAndFind

Excellent.


5 posted on 04/10/2020 6:10:36 PM PDT by Trumpisourlastchance
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To: SeekAndFind

How many hacking attempts are underway right now to get into the files of IHU Méditerranée Infection in order to find some connection to Trump?


6 posted on 04/10/2020 6:10:49 PM PDT by bramps (It's the Islam, stupid!)
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To: SeekAndFind

It’s a pretty big anecdote.


7 posted on 04/10/2020 6:11:50 PM PDT by Rio
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To: hinckley buzzard

Enemedia will scream: “See, we told you so, it’s a deadly drug. It killed 4.3% of patients!”


8 posted on 04/10/2020 6:12:58 PM PDT by rfp1234 (Democratus Partitus Delendus Est)
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To: hinckley buzzard

French President Macron visits French doctor behind hydroxychloroquine coronavirus 'cure' touted by Trump

EXCERPT

President Emmanuel Macron visited a French doctor in Marseille on Thursday whose work on a drug normally used for auto-immune diseases has been promoted by US President Donald Trump as a potential weapon against Covid-19 but has split medical opinion.

Macron, who met Professor Didier Raoult at his Marseille hospital behind closed doors, did not endorse the treatment, his office said, adding that it was too early for the French government to assess its effectiveness.

"One visit does not legitimate a scientific protocol, a visit simply marks the head of state's interest for these clinical trials, whether they are promising or not," a presidential adviser said.

But the presidential visit is a boost for the Marseille professor, who has become one of France's best-known doctors after his treatment was cited in a tweet by Trump, calling it "one of the biggest game-changers in the history of medicine".

His research team has published data showing that out of 80 mild Covid-19 patients treated with hydroxychloroquine and azithromycin, 93 percent had no detectable levels of the virus after eight days.

DR. DIDIER RAOULT


9 posted on 04/10/2020 6:13:39 PM PDT by SeekAndFind (look at Michigan, it will)
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To: SeekAndFind

Dr Didier has been doing his part to “social distance” from barbers for years.


10 posted on 04/10/2020 6:19:01 PM PDT by irishjuggler
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To: SeekAndFind
This would seem to be the only line that really matters:

Mortality was significantly lower in patients who had received > 3 days of HCQ-AZ than in patients treated with other regimens both at IHU and in all Marseille public hospitals (p< 10^(-2)).

It sounds very promising. If I'm reading it right, they are saying there is less than 1 in 100 chance the results happened by chance alone.

However it's a bit weird that they don't put that fact right up at the top, and they don't give any numbers for the comparison, i.e. among those patients not treated with HCQ, the death rate was 2% or 1% or whatever.

11 posted on 04/10/2020 6:23:53 PM PDT by edwinland
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To: irishjuggler
Here's Dr. Didier (the one in the middle) before he misplaced his razor...


    

12 posted on 04/10/2020 6:29:24 PM PDT by Songcraft
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To: SeekAndFind

Consider that drugs touted as miracle cures often work on less than half the trial folks and have many serious, serious side effects.

Of course muppet media doesn’t provide context.


13 posted on 04/10/2020 6:29:51 PM PDT by Secret Agent Man (Gone Galt; Not Averse to Going Bronson.)
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To: Diogenesis

Better to be anecdotally alive than scientifically dead!


14 posted on 04/10/2020 6:36:04 PM PDT by etcb
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To: SeekAndFind
5 patients died (0.47%) (74-95 years old)

That is very impressive.

15 posted on 04/10/2020 6:39:25 PM PDT by SmokingJoe
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To: SeekAndFind

Check out the news on this guy. He is getting a lot of heat. I can’t believe anything so obvious would be challenged like it is.


16 posted on 04/10/2020 6:45:44 PM PDT by Nifty
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To: irishjuggler

Dr Didier has been doing his part to “social distance” from barbers for years


LOL


17 posted on 04/10/2020 6:46:22 PM PDT by Freedom56v2
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To: Freedom56v2

Btt


18 posted on 04/10/2020 6:50:34 PM PDT by KSCITYBOY (The media is corrupt)
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To: SeekAndFind; MHGinTN

Bkmk and ping.


19 posted on 04/10/2020 7:16:48 PM PDT by BDParrish ( Please correct me! I never learned anything from anybody who already agreed with me.)
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To: Nifty

It really is a sign of how insane and split our world has become. It’s in plain sight to see and yet the liberals and Trump haters are doing their darndest to discount the drug. It’s really unbelievable and there is no hope of reconciliation with the left


20 posted on 04/10/2020 7:29:45 PM PDT by pangaea6
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