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Stem Cells May Be Key to Cancer
NY Times ^ | 02.21.06 | NICHOLAS WADE

Posted on 02/23/2006 10:45:31 PM PST by Coleus

One day, perhaps in the distant future, stem cells may help repair diseased tissues. But there is a far more pressing reason to study them: stem cells are the source of at least some, and perhaps all, cancers.

At the heart of every tumor, some researchers believe, lie a handful of aberrant stem cells that maintain the malignant tissue.  The idea, if right, could explain why tumors often regenerate even after being almost destroyed by anticancer drugs. It also points to a different strategy for developing anticancer drugs, suggesting they should be selected for lethality to cancer stem cells and not, as at present, for their ability to kill just any cells and shrink tumors.

"I think this is one of the most interesting developments in cancer research in the last five years," says Robert Weinberg, a cancer geneticist at the Whitehead Institute in Cambridge, Mass. "I think more and more people are accepting it and evidence is accumulating that cancer stem cells exist in a variety of tumors."  The idea that cancer cells possess the same properties as stem cells has been around for many years. Only recently have biologists developed techniques for identifying stem cells and their presence in tumors.

Cancer stem cells were first identified in certain types of leukemia in 1997 by John Dick and colleagues at the University of Toronto. They were harder to spot in solid tumors because biologists did not possess the means of recognizing the markers —

(Excerpt) Read more at nytimes.com ...


TOPICS: Business/Economy; Culture/Society
KEYWORDS: adultstemcells; cancer; cancerstemcells; leukemia; stemcells
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1 posted on 02/23/2006 10:45:32 PM PST by Coleus
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To: 2ndMostConservativeBrdMember; afraidfortherepublic; Alas; al_c; american colleen; annalex; ...


2 posted on 02/23/2006 10:46:08 PM PST by Coleus (What were Ted Kennedy & his nephew doing on Good Friday, 1991? Getting drunk and raping women)
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To: Coleus

I find it strange that there is no mention (that I could see) of whether this was coming from embryonic stem cells, adult stem cells, or stem cells from amniotic fluid, umbilical cords, or marrow.


3 posted on 02/23/2006 10:53:25 PM PST by GOPyouth (De Oppresso Liber! The Tyrant is captured!)
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To: GOPyouth
I looked too and couldn't find anything..It's the biased NY Times, since they didn't mention the source, I'm "guessing" the cells would be from non-embryonic sources. 

Embryonic Stem cells are primitive, grow quickly like cancer cells,  cause teratomas ,  and death.
4 posted on 02/23/2006 11:02:58 PM PST by Coleus (What were Ted Kennedy & his nephew doing on Good Friday, 1991? Getting drunk and raping women)
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To: PatrickHenry; b_sharp; neutrality; anguish; SeaLion; Fractal Trader; grjr21; bitt; KevinDavis; ...
FutureTechPing!
An emergent technologies list covering biomedical
research, fusion power, nanotech, AI robotics, and
other related fields. FReepmail to join or drop.

5 posted on 02/23/2006 11:06:10 PM PST by AntiGuv
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To: djreece

marking


6 posted on 02/23/2006 11:08:23 PM PST by djreece ("... Until He leads justice to victory." Matt. 12:20c)
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To: Coleus

Adult stem cells ahve been routinely used for more than 8 years for the treatement of the IMMUNO problems that come with cancer treatments.

The stem cell messiah is completely lacking. There have been frankensteinien experiments that have accomplished nothing, the only true use of stemcells as yet has been built on the idea, that if adult stemcells are reintroduced into a weakened immuno system, they will support the anti infenction system of the human body.

If there is anythimg more than an ear or a prostate on a rat, then why is it that Stem Cell, regeneration (called transplants) is only used on immuno deficiencies created by other treatments.

I DO believe there is a great potential for stem cell therapy, but it takes more than this to convince me that stem cells have gone uber ninja generalist in their affects, without something as valid as the other treatments built on adult stems.

People who don't have jobs? tend to require to be published. Doesn't matter if you accomplish anything, just PUBLISH something, THEN you are an academic.

I don't know the source, but I loved the term, "academic idiot"

Okay, I have been yammering, sorry.


7 posted on 02/23/2006 11:09:33 PM PST by wickedpinto (The road map to peace is a straight line down an Israeli rifle.)
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To: Coleus

The Slimes is slowly building the case to make cancer Bush's fault, too. Along with everything else, of course.


8 posted on 02/23/2006 11:09:42 PM PST by KellyAdmirer
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To: Coleus
Articles I read up on for an article I had to write for my ethics class discussed 2 major problems resulting from using embryonic stem cells. 1. Causing tumors in lab rats. 2. The lab rats rejecting the cells.

I don't know if things have changed, but as of when these articles were written, humans weren't being used in these studies b/c of these two issues.

9 posted on 02/23/2006 11:16:50 PM PST by GOPyouth (De Oppresso Liber! The Tyrant is captured!)
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To: Coleus

Why we just get it over with and say that stem cells can cure everything - including the flu and common cold. heh.


10 posted on 02/23/2006 11:39:01 PM PST by BoBToMatoE
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To: BoBToMatoE
I have no doubt that stem cells can probably help scientists come up with solutions to medical problems. The main issue is whether stem cells harvested/gathered from a source other than an embryo are going to be effective.

In other words, are embryonic stem cells necessary?

11 posted on 02/23/2006 11:41:52 PM PST by GOPyouth (De Oppresso Liber! The Tyrant is captured!)
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To: KellyAdmirer

"he Slimes is slowly building the case to make cancer Bush's fault, too. Along with everything else, of course"

Bingo! And don't forget, algore INVENTED stem cells. His genius and scientific breakthrough for the world ended when he won in 2000 but had the election stolen from him...by his arch-enemy the SCOTUS.

BUAHAHAHAHAHAH. Thank you algore, for keeping my handle valid.


12 posted on 02/23/2006 11:58:35 PM PST by goresalooza (Nurses Rock!)
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To: Coleus
Actually there was a news flash about the probably cure for cancer already.
Seems scientists have been wanting to know what caused cancer cells to start up and grow. What do they look for in order to present themselves.
I believe they said that it was found to be a particular enzyme or protein and now they found it.
They showed a picture of it and said by targeting this alone, new types of Chemo drugs that don't hurt the patient or good tissue will be made in the near future and it will probably be the cure for cancer.
With the enzyme/protein gone, the cancer goes away.
13 posted on 02/24/2006 12:32:43 AM PST by A CA Guy (God Bless America, God bless and keep safe our fighting men and women.)
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To: Coleus

Here you go.

http://www.rockymountainnews.com/drmn/local/article/0,1299,DRMN_15_4446435,00.html

Cancer cure


14 posted on 02/24/2006 12:45:36 AM PST by A CA Guy (God Bless America, God bless and keep safe our fighting men and women.)
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To: GOPyouth
I find it strange that there is no mention (that I could see) of whether this was coming from embryonic stem cells, adult stem cells, or stem cells from amniotic fluid, umbilical cords, or marrow.

The NYT would rather destroy all the reseach and have it banned rather than have treatments that don't kill the unborn.

15 posted on 02/24/2006 12:54:52 AM PST by Paul C. Jesup
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To: Paul C. Jesup

See 14


16 posted on 02/24/2006 1:00:56 AM PST by A CA Guy (God Bless America, God bless and keep safe our fighting men and women.)
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To: A CA Guy
Adult Stem Cells are now used in over 64 different treatments.

Also, it sounde like the enzyme telomerase is what causes cancer, not the adult stems. If doctors can find a way to block the enzyme, they have just cured cancer.

And Jacobs is a genius in the way he got a piece of that enzyme.

17 posted on 02/24/2006 1:24:02 AM PST by Paul C. Jesup
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To: Paul C. Jesup

Yes, I saw a news bit with a picture of the enzyme, and they said the plan is to attack the enzyme only, which would kill the source for the cancer while not hurting the person or normal healthy tissue.

I think this can be accomplished fast now that they found this.

I never liked the unborn stem cell usage.


18 posted on 02/24/2006 1:27:03 AM PST by A CA Guy (God Bless America, God bless and keep safe our fighting men and women.)
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To: GOPyouth
I find it strange that there is no mention (that I could see) of whether this was coming from embryonic stem cells, adult stem cells, or stem cells from amniotic fluid, umbilical cords, or marrow.

That's because the article is discussing the discovery of cancer stem cells in tumors & various other types of cancer.

19 posted on 02/24/2006 1:32:17 AM PST by elli1
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To: A CA Guy

The draw back to such a treatment thought is that if they are not careful, their treatments may not just attack that enzyme and it make also attack other normal functions on how the cell divides, causing the cell to no longer divide and you have celular decay and cell death.


20 posted on 02/24/2006 1:33:29 AM PST by Paul C. Jesup
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