Keyword: stemcells
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Washington, DC (LifeNews.com) -- Two consumer groups have filed an appeal with the U.S. Patent and Trade Office contesting its March ruling upholding the exclusive patents for stem cells. The office said the Wisconsin Alumni Research Foundation, which holds the original patent on embryonic stem cells, can keep its patents. The patents cover all embryonic stem cells used in the United States and any scientists or research firms wanting them must pay WARF's hefty prices for them. The California-based Foundation for Taxpayer and Consumer Rights and the Consumer Watchdog Foundation are the groups behind the lawsuit and it said WARF...
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Researchers at the Joslin Diabetes Center have demonstrated for the first time that transplanted muscle stem cells can both improve muscle function in animals with a form of muscular dystrophy and replenish the stem cell population for use in the repair of future muscle injuries. "I'm very excited about this," said lead author Amy J. Wagers, Ph.D., Principal Investigator in the Joslin Section on Developmental and Stem Cell Biology, principal faculty member at the Harvard Stem Cell Institute and Assistant Professor of Stem Cell and Regenerative Biology at Harvard University. "This study indicates the presence of renewing muscle stem cells...
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Barcelona, Spain: For the first time in the world scientists have succeeded in developing human embryonic stem cells (hESCs) from a single cell, or blastomere, of a 4-cell stage embryo, the 24th annual conference of the European Society of Human Reproduction and Embryology heard today (Wednesday 9 July). Dr. Hilde Van de Velde, from the Vrije Universiteit Brussel (VUB), Brussels, Belgium, said that their research meant that it might be possible in the future to produce hESC lines at an earlier stage without destroying the embryo. Blastomeres are formed in the very early stages of embryonic development. About 24 hours...
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In the ongoing debate about stem cell research, few people differentiate between adult stem cells and embryonic stem cells. Also, few know that there are over 70 successful treatments from adult stem cells and none from embryonic.1What has many up in arms is that the production of embryonic stem cells endangers the life of a very small, but distinctly human, person. Once a human egg has been fertilized, a new cell results, called a zygote. This single cell contains all the instructions required to mature and develop a full-term baby and is therefore rightly considered an immature person. The...
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There's been a lot of controversy over the use of embryonic stem cells in recent years, but adult stem cells, which few people oppose using, are already giving some patients a new lease on life. Donald Reid is hoping adult stem cells will give him more time. The 57-year-old has clogged arteries and heart disease so bad he's not a candidate for surgery. Instead, he's joined an experimental study. It involves a machine that takes his blood and pulls out stem cells. But these aren't stem cells from an embryo. These are Donald's own adult stem cells. In the coming...
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Study: Stem Cells Used To Fix Your Broken Heart It's Called The Marvel Study The Largest Clinical Trial Investigating Adult Stem Cells To Treat Congestive Heart Failure For More Info, Call Jim Moran Heart & Vascular Center At (954) 229-8400 MIAMI (CBS4) ― Doctors are discovering a new way to fix your broken heart. A study is underway in South Florida that could revolutionize the way heart attack patients help their damaged hearts by using their own stem cells. It's called The Marvel Study and under the direction of Dr. Alan Neiderman with the Jim Moran Heart & Vascular Research...
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Mumbai: Seven years after its inception amid much fanfare, Reliance Life Sciences, or RLS, is finally rolling out stem cell-based therapies in India, beginning with a treatment that can restore or improve vision. “This is the first commercial stem cell treatment in ophthalmology in the country,” said K.V. Subramaniam, CEO and president, RLS, part of the Mukesh Ambani-led Reliance group. The company, which has invested around Rs1,000 crore in the business, has lined up other stem cell therapies for cardiac infarction, diabetic ulcer, and stable vitiligo or leukoderma (a skin disease), among others, to be offered in clinics in the...
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Spine surgeons at Pine Creek Medical Center in Dallas have established themselves as the leaders of a cutting-edge surgical procedure that utilizes a patient's own adult stem cells to regenerate tissue. Doctors Douglas Won, Michael Rimlawi, and Francisco J. Battle, all spine surgeons, have extensive experience in harvesting adult stem cells during routine spinal procedures and delivering those cells back to their patients to aid in the treatment of severe back pain. According to the World Research Group, disorders of the spine are one of the largest public health problems in the U.S. and as the population ages, incidents of...
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Massachusetts Gov. Deval Patrick signed a $1 billion embryonic stem cell research bill on Monday. The measure is meant to provide the controversial research with more taxpayer money after President Bush refused to force taxpayers to fund the destruction of human life. Patrick pushed the plan through the state legislature to force the state's taxpayers to fund embryonic stem cell research to the tune of $1 billion over 10 years.He said he wanted the northeastern state to keep up with others like California, Illinois, and neighboring Connecticut, which have publicly funded the grisly research. Under his plan, the state would...
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NICE, France: In patients with multiple sclerosis (MS), immunosuppressive therapy followed by autologous haematopoietic stem cell transplantation elicited high response rates and improved quality of life for up to 6 years. The results of the study were presented here at the 18th Meeting of the European Neurological Society (ENS) by Tatiana Ionova, MD, PhD, Department of Haematology, Pirogov National Medical Surgical Center, Moscow, Russia. During the last decade, high-dose immunosuppressive therapy followed by autologous haematopoietic stem cell transplantation has been used with increasing frequency as a therapeutic option for patients with MS. "The aim of the study was to assess...
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New York is set to spend $600 million in taxpayer dollars on stem cell research. A recently released draft plan drooling over the potential of embryonic cells to cure a variety of diseases has drawn this blast from Rev. Ruben Diaz, the state senate's sole pro-life Democrat: June 13, 2008Judy Doesschate, J.D.Director of Board OperationsWadsworth CenterNew York State Department of HealthEmpire State Plaza, Box 509Albany, NY 12208-0509Dear Ms. Doesschate:This letter is to express my response to the Empire State Stem Cell Board’s strategic framework that will guide New York State’s $600 Million, 11-year investment in stem cell research. The...
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Dr. Rodriguez discussed use of stem cells for treating SUI (Stress Urinary Incontinence). A stem cell is embryonic, adult, or engineered. Embryonic stem cells come from the blastocyst which is totipotent or pluripotent. These cells are immortal, identical clonal cells with long-term self renewal. Controversies include possible tumor formation, the difficulty maintaining cell cultures and ethical issues. Embryonic stem cells can differentiate into ectoderm, mesoderm and endoderm. Adult stem cells include hematopoetic stem cells, such as derived from bone marrow. This requires a bone marrow harvest, with low yield and difficulty to expand clones. A variety of other tissues have...
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Australian scientists have discovered that stem cells found in the back of a patient's nose can produce the chemical which is missing in people with Parkinson's disease. Parkinson's disease occurs when the brain cells that produce the chemical dopamine stop working. Without dopamine, nerve cells cannot function, leading to muscle problems. Researchers from Griffith University and the University of Queensland harvested adult stem cells from the noses of Parkinson's disease patients. They found that once the nose cells were cultured and infused into animals with Parkinson's disease, the cells began to produce dopamine. Professor Peter Silburn from the University of...
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iZumi Bio has agreed to license some patents from the J. David Gladstone Institutes as they begin to work together on new adult stem cell technology involved in devising cardiovascular therapies. ReportStem cell transplants were used to restore the sight of six blind patients at a London hospital. StorySome 2,500 delegates attended the recent International Society for Stem Cell Research in Philadelphia. And insiders say that the development of induced pluripotent stem cells has clearly energized the entire field. ReleaseIn a new study regarding age-related diseases, researchers identified two key regulatory pathways that control how well adult stem cells...
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Adult stem cell research, for the pro-life community, is ethically superior to embryonic stem cell research because it doesn't involve the destruction of human life. Scientists at Griffith University in Australia are advancing the notion that its effectiveness is superior as well. The researchers published an article on Friday in the medical journal Stem Cells showing that the use of adult stem cells may be getting closer to a cure, or at least an effective treatment, for Parkinson's. Their new studies show adult stem cells from a patient's own nose could treat their condition. The paper showed the finding that...
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Once an Embryo… June 23rd, 2008 by Fr. Frank Pavone The US bishops have issued a very clear statement on embryonic stem cell research. It does not dwell upon the scientific nuances of the issue, but rather assists the reader to focus on the moral issues involved. The statement is not marked by condemnation, but rather by explanation. It is not a rejection of research or of those who stand to benefit from research, but rather a call to pursue the well being of those very individuals by preserving the moral standards that protect their dignity and that of the...
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The Perth scientist who made the world-first discovery that human breast milk contains stem cells is confident that within five years scientists will be harvesting them to research treatment for conditions as far-reaching as spinal injuries, diabetes and Parkinson’s disease. But what Dr Mark Cregan is excited about right now is the promise that his discovery could be the start of many more exciting revelations about the potency of breast milk. He believes that it not only meets all the nutritional needs of a growing infant but contains key markers that guide his or her development into adulthood. “We already...
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BERKELEY – Old muscle got a shot of youthful vigor in a stem cell experiment by bioengineers at the University of California, Berkeley, setting the path for research on new treatments for age-related degenerative conditions such as muscle atrophy or Alzheimer's and Parkinson's diseases. Old muscles renewedIrina Conboy and Morgan Carlson have learned how to trigger the rejuvenation of old, damaged muscles. View full-size videoIn a new study published June 15 in an advanced online issue of the journal Nature, researchers identified two key regulatory pathways that control how well adult stem cells repair and replace damaged tissue. They then...
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The US bishops have issued a very clear statement on embryonic stem cell research. It does not dwell upon the scientific nuances of the issue, but rather assists the reader to focus on the moral issues involved. The statement is not marked by condemnation, but rather by explanation. It is not a rejection of research or of those who stand to benefit from research, but rather a call to pursue the well being of those very individuals by preserving the moral standards that protect their dignity and that of the rest of us. The statement reminds us that there is...
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How America came to accept using human embryos for research In the ten years since Dr. James Thomson at the University of Madison first procured human embryonic stem cells (hESCs), support for the prospect of using human embryos and fetuses for research purposes has gradually seeped into the American mindset to the point at which it is now broadly tolerated, if not openly endorsed, especially in the political arena, in academia, and certainly within the scientific community. [1] As we continue to advance as a nation into the age of developmental biology there is reason to fear that Americans are...
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Stem Cells Could Replace Plastic Surgery Silicone breast implants and botox could one day be things of the past thanks to promising new techniques that would allow doctors to work plastic surgery miracles using only a patient's own stem cells. Traditionally, plastic and reconstructive surgery has relied heavily on fillers. Bags full of saline or silicone are used to plump up breasts. Chunks of fat are taken from one area of the body and grafted into another. These techniques, which like other body enhancement procedures have soared in popularity in recent years, can work successfully but they also have drawbacks....
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The pharmaceutical giant Pfizer has announced that it is funding a new adult stem-cell treatment that could treat diabetes-induced retinal damage, a leading cause of blindness. Forbes Magazine says that Pfizer is funding the creation of a San Diego biotech company named EyeCyte to develop stem-cell treatments for eye diseases. The company will base its work upon Scripps Research Institute ophthalmologist Martin Friedlander’s research involving stem-cells from blood and bone marrow. EyeCyte will receive about $3 million from Pfizer, which in return has the right of first refusal regarding the new company’s products. In animal experiments, adult stem-cells have shown...
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A recent medical breakthrough at UNC may help thousands every year whose broken bones do not heal. Researchers who transplanted adult mouse stem cells into mice with fractured bones showed that the cells could help heal the fractures. Anna Spagnoli, associate professor of pediatrics and biomedical engineering at UNC and senior author of the study, said it was meant to determine whether adult stem cells could be used to improve the healing tissue at a fractured site and whether the cells went directly to the injury once transplanted. She said that as a pediatrician, she has worked with children...
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Two Canadians have been injected with a genetically modified version of their own adult stem cells in an attempt to cure pulmonary hypertension, a rare, debilitating lung disease. The procedure, which has successfully cured rats with pulmonary hypertension, has halted the progress of the disease in the patients. The first patient, who has had the disease for 13 years, is reporting no ill effects from the treatment and has seen her condition improve. Researchers are hopeful that the treatment eventually will reverse or even cure the disease. "The use of ethical stem cells to treat disease is a positive and...
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Breakthrough: Adult Stem Cells & Parkinson’s Great - and, for anyone following the stunning medical advances being made thanks to ADULT Stem Cell Research - unsurprising news on the Parkinson’s front. Just as numerous spinal cord injuries are being successfully treated with ASC taken from nasal cavities, it looks there sufferers of Parkinson’s Disease may be helped, too.Scientists Say Cure for Parkinson's Disease Right under Their Noses SYDNEY, Australia, June 12, 2008 (LifeSiteNews.com) - New research on stem-cell therapy shows scientists have found that the cure for Parkinson’s disease may lie right under one’s nose - or rather, in it....
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After 21 years of unsuccessful heart treatments, including several heart procedures, 68-year-old Coenie de Jongh was desperate. So when his cardiologist suggested a last-resort experimental therapy, it represented a literal life line. Coenie, from Bloubergstrand near Cape Town, had his first heart attack at the young age of 40. A bypass operation followed and his condition improved, but seven years later Coenie’s health started deteriorating again. More operations and more intense treatment followed, but in 2002 his health took a real turn for the worse. His condition was so bad he struggled to find a cardiologist who was willing to...
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Participants in a Federal Drug Administration (FDA) protocol at TCA Cellular Therapy utilizing stem cells to treat lower limb ischemia are experiencing increased mobility and decreased pain in lower legs. Lower limb ischemia is a condition where plaque build-up causes decreased circulation in the lower leg. Symptoms of the condition include intense pain and swelling. Study participants may have had different factors that contributed to their condition: a family history of Peripheral Artery Disease (PAD), history of smoking and other vascular conditions. Common among them however, were that more traditional treatments (utilizing stents and grafts) were ineffectual and that the...
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Like the masterless samurai for whom it is named, the protein Ronin chooses an independent path, maintaining embryonic stem cells in their undifferentiated state and playing essential roles in genesis of embryos and their development, said Baylor College of Medicine researchers who reported on this novel cellular regulator in the current issue of the journal Cell. Three proteins - Oct4, Sox2 and Nanog -- had previously been considered the "master" regulators of embryonic stem cells, but "Ronin could be as important as these three," said Dr. Thomas Zwaka, assistant professor in the Stem Cells and Regenerative Medicine (STaR) Center at...
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SAN DIEGO – A team of San Diego scientists has moved embryonic stem cell research a step closer to helping repair the brains of stroke victims and people with diseases such as Parkinson's and Alzheimer's. The team, led by the Burnham Institute's Stuart Lipton, figured out how to coax the embryonic stem cells of mice to become nerve cells that, when transplanted into a mouse brain damaged by stroke, link themselves to the existing network of neurons. The mice showed therapeutic improvement, and none of them developed tumors, which has been a problem associated with the implantation of stem cells,...
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Eight months after state officials broke ground on New Jersey's new center for stem cell research, the once-heralded $150 million project has quietly been put on indefinite hold. Despite continuing assurances that the 18-story tower in New Brunswick would remain on track -- even after voters rejected proposals last year to finance $450 million in stem cell science grants -- state officials behind the scenes pulled back millions in construction funding for the research facility late last year. They now acknowledge they are re-evaluating the entire project. Gov. Jon Corzine said the project is in limbo and could not offer...
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LifeNews.com Note: William Beckman is the executive director of the Illinois Right to Life Committee. Opinion articles like this one do not necessarily reflect the views of LifeNews.com. The June 19, 2008 headline reads “US doctors kill skin cancer with cloned T-cells.” Does this suggest that human cloning of embryonic stem cells has been successful in treating skin cancer? Absolutely not! The details of the New England Journal of Medicine report that generated this news coverage reveal that adult stem cells obtained from the patient were used. As reported in ScienceDaily, researchers “removed CD4+ T cells, a type of white...
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In an approach that could become a new treatment for the 10 to 20 percent of people whose broken bones fail to heal, researchers at the University of North Carolina at Chapel Hill have shown that transplantation of adult stem cells can improve healing of fractures. Adult stem cells are specialized cells with the ability to regenerate tissue in response to damage. However, many patients lack sufficient numbers of these cells and thus cannot heal properly. Researchers have used adult stem cells in a few cases to improve fracture healing, but further studies were needed to show that this method...
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Stem cells may force Crohn's disease into retreat, say Long Island medical investigators who are embarking on a pioneering analysis that targets patients who've failed other therapies. Cases of Crohn's disease have skyrocketed since World War II, jumping tenfold in the United States and raising questions about the disease's genetics and demography. It is one of two disorders -- the other is ulcerative colitis -- that are known as inflammatory bowel diseases. Before the 20th century there was no recorded evidence of either. Dr. Robert Richards, director of clinical research in the gastroenterology division at Stony Brook University Medical Center,...
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President Bush may follow in the footsteps of his brother Jeb and convert to Catholicism, several European papers are reporting. In the wake of the president’s visit to see Pope Benedict XVI at the Vatican, Italian newspapers, citing Vatican sources, said Bush was open to the idea of converting to Catholicism. The Italian newspaper Il Foglio referred to such talk about Bush’s possible conversion and stated that “anything is possible, especially for someone reborn like Bush.” Noting that Tony Blair converted to Catholicism after leaving office as Britain’s prime minister last year, the paper also stated that “if anything happens,...
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MOUNTAIN HOME, Ark. — When 9-year-old Kacie Sallee saw her father's face more clearly for the first time in her life, she had a question. "She said, 'Is that what he looks like?'" said her mother, Marinda Sallee. Kacie, who is blind, returned last week from China, where she received umbilical-cord stem cell treatment in hopes of improving her eyesight. The nearly four-week trip and medical treatment was paid through $60,000 in local donations. Kacie was born with septo-optic dysplasia, an underdevelopment of the optic nerve and pituitary gland. She could see bright colors out of her right eye but...
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ORLANDO, Fla. (CNS) -- Opening their spring general meeting in Orlando, members of the U.S. Conference of Catholic Bishops got an interim report on the causes and context of child sexual abuse by priests and made quick work of proposals to revisit the ethical guidelines on feeding tubes and to declare a National Catholic Charities Sunday in 2010. In the first morning session of the June 12-14 assembly at the Hyatt Regency Grand Cypress, the bishops also took a preliminary look at two documents they will vote on later in the meeting. The first was a 700-page draft translation of...
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AUSTRALIA'S first licences to clone human embryos could be granted as early as this week. A National Health and Medical Research Council panel met in Canberra on Friday to consider applications from two separate research groups. The green light for the controversial science could lead to a cure for such afflictions as Alzheimer's, Parkinson's and Huntington's diseases and type 1 diabetes in less than 10 years. A Monash University team and another based at the Melbourne lab of the Australian Stem Cell Centre have each partnered with Sydney IVF to submit licence requests. The teams want permission to create cloned...
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"Adult stem cells cure and treat more than 70 diseases and are involved in almost 1,300 human clinical trials. Scientists also keep discovering that adult stem cells are capable of creating a wider variety of mature cells. Perhaps the most promising of these was announced in the January issue of Nature Biotechnology." From article, "Code of Silence", under articles heading.
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Success in mice could be a breakthrough for disorders such as multiple sclerosis. Human donor cells (red) spread through the mouse brains and trigger their repair.Windrem et al./Cell Stem Cell 5 June 2008 Human stem cells have been used to correct abnormal brain development in mice with fatal brain disorders, offering hope for treating a range of neurological disorders including some deadly childhood genetic diseases. Those behind the new treatment hope that human clinical trials could be just a few years away. The treatment uses human glial progenitor cells — cells that can differentiate into the glial cells that, among...
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Life is regenerative, by definition. But by and large, humans lack the regenerative capacity of creatures such as newts and hydra. Although some of our cells have the innate ability to replenish themselves — and, by doing so, to repair ageing and injured tissues and organs — most of the body's cells form the specialized cell type they are destined for and then go into lock down. Having said that, humans do have organs and tissues, such as liver and skin, that regenerate well. Unfortunately, the insults of injury, disease and age wreak havoc on those that don't. This explains...
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At least two modules of genes promote stemness Two separate groups of genes seem able to promote stemness. And while most adult tissue stem cells share one program, embryonic stem cells and at least some human cancer cells share another. In fact, one well-known oncogene, myc, was able to both initiate the embryonic stem cell module and generate cancer stem cells. These findings, reported recently by researchers at Stanford University in California and the Weizmann Institute of Science in Israel, support the still-controversial hypothesis that embryonic stem cells and at least some cancer stem cells share a common genetic program....
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Research from the University of Southern California (USC) has discovered a new mechanism to allow embryonic stem cells to divide indefinitely and remain undifferentiated. The study, which will be published in the May 22 issue of the journal Nature, also reveals how embryonic stem cell multiplication is regulated, which may be important in understanding how to control tumor cell growth. “Our study suggests that what we believe about how embryonic stem cell self-renewal is controlled is wrong,” says Qi-Long Ying, Ph.D., assistant professor of Cell and Neurobiology at the Keck School of Medicine of USC, researcher at the Eli and...
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Bone marrow stem cells waver before committing to develop into specialized blood cellsIf two roads diverged in a yellow wood, random fluctuations would influence which road stem cells traveled. A new understanding of how stem cells choose among their possible fates could aid development of stem cell therapies for diseases, scientists say. A type of adult stem cell in bone marrow can develop along one of two paths: either the red or white blood cell lineages. Scientists have wondered why some bone marrow cells follow one path while other, seemingly identical cells go down the other. New research shows that...
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While it has long been known that embryonic stem cells have the ability to develop into any kind of tissue-specific cells, the exact mechanism as to how this occurs has heretofore not been demonstrated. Now, researchers at the Hebrew University of Jerusalem and elsewhere have succeeded in graphically revealing this process, resolving a long-standing question as to whether the stem cells achieve their development through selective activation or selective repression of genes. The collaborative research group, which included Dr. Eran Meshorer of the Department of Genetics at the Silberman Institute of Life Sciences at the Hebrew University of Jerusalem, has...
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Gordon Brown backs animal-human hybrids By Subhajit Banerjee and agencies Last Updated: 2:31PM BST 18/05/2008 Gordon Brown today strongly defended the medical use of animal-human hybrid embryos, ahead of a key Commons vote on the issue. The Prime Minister said that stem cell research was an "inherently moral endeavour" and a "profound opportunity" to save and transform millions of lives. "Britain is at the forefront of this research and responsible for much of the worldwide progress," he wrote in The Observer newspaper. The premier supports scientists who want to insert the nuclei of human cells into animal eggs,...
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A drug that targets the cell surface receptors that play an important role in many types of cancer can bring about significant tumour regression in breast cancer after only six weeks of use, a scientist told the 6th European Breast Cancer Conference (EBCC-6) today. Dr. Angel Rodriguez, from the Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, USA, said that the work demonstrated for the first time that the tyrosine kinase inhibitor lapatinib could decrease tumour-causing breast cancer stem cells in the primary breast cancers of women receiving neoadjuvant treatment (treatment given before the primary surgery for...
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Human Dignity & the Sanctity of Life Overturning Roe v. Wade John McCain believes Roe v. Wade is a flawed decision that must be overturned, and as president he will nominate judges who understand that courts should not be in the business of legislating from the bench. Constitutional balance would be restored by the reversal of Roe v. Wade, returning the abortion question to the individual states. The difficult issue of abortion should not be decided by judicial fiat. However, the reversal of Roe v. Wade represents only one step in the long path toward ending abortion. Once the...
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Until about a decade ago, there was only one way to make an embryo—the old-fashioned technique of combining an egg with a sperm. Then came Dolly the cloned sheep in 1996. Scottish scientists created her by injecting the nucleus of a breast cell from one sheep into the enucleated egg of another sheep. Dolly was essentially genetically identical to the donor of the breast cell nucleus. Since then researchers have used reproductive cloning to produce mice, cats, dogs, horses, cows, goats, pigs, and other mammals. As valuable as reproductive cloning is for producing livestock and research animals, most researchers were...
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In what could signal a further shift in the global stem cell debate, lawmakers in an Australia state have rejected legislation allow the cloning of human embryos for research purposes. This week's vote in the Western Australia capital, Perth, is believed to be one of the first times the embryonic cloning issue has been considered by a legislature anywhere in the world since reports of a major research breakthrough last November prompted new questions about the need to use embryos at all. The issue will be under discussion on Capitol Hill again on Thursday, when a health subcommittee of the...
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Governor Paterson announced $109 million in funding for stem cell research yesterday as part of a $600 million initiative approved in last year’s budget. ... Yesterday’s announcement coincided with a convocation ceremony at Memorial Sloan-Kettering Cancer Center. “Human embryonic stem cells offer an unprecedented opportunity to study all aspects of human development,” the hospital’s president, Dr. Harold Varmus, said in a statement.
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