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Blue-eyed humans have a single, common ancestor
University of Copenhagen ^ | January 30, 2008 | Unknown

Posted on 01/30/2008 2:10:37 PM PST by decimon

New research shows that people with blue eyes have a single, common ancestor. A team at the University of Copenhagen have tracked down a genetic mutation which took place 6-10,000 years ago and is the cause of the eye colour of all blue-eyed humans alive on the planet today. What is the genetic mutation

“Originally, we all had brown eyes”, said Professor Eiberg from the Department of Cellular and Molecular Medicine. “But a genetic mutation affecting the OCA2 gene in our chromosomes resulted in the creation of a “switch”, which literally “turned off” the ability to produce brown eyes”. The OCA2 gene codes for the so-called P protein, which is involved in the production of melanin, the pigment that gives colour to our hair, eyes and skin. The “switch”, which is located in the gene adjacent to OCA2 does not, however, turn off the gene entirely, but rather limits its action to reducing the production of melanin in the iris – effectively “diluting” brown eyes to blue. The switch’s effect on OCA2 is very specific therefore. If the OCA2 gene had been completely destroyed or turned off, human beings would be without melanin in their hair, eyes or skin colour – a condition known as albinism. Limited genetic variation

Variation in the colour of the eyes from brown to green can all be explained by the amount of melanin in the iris, but blue-eyed individuals only have a small degree of variation in the amount of melanin in their eyes. “From this we can conclude that all blue-eyed individuals are linked to the same ancestor,” says Professor Eiberg. “They have all inherited the same switch at exactly the same spot in their DNA.” Brown-eyed individuals, by contrast, have considerable individual variation in the area of their DNA that controls melanin production.

Professor Eiberg and his team examined mitochondrial DNA and compared the eye colour of blue-eyed individuals in countries as diverse as Jordan, Denmark and Turkey. His findings are the latest in a decade of genetic research, which began in 1996, when Professor Eiberg first implicated the OCA2 gene as being responsible for eye colour. Nature shuffles our genes

The mutation of brown eyes to blue represents neither a positive nor a negative mutation. It is one of several mutations such as hair colour, baldness, freckles and beauty spots, which neither increases nor reduces a human’s chance of survival. As Professor Eiberg says, “it simply shows that nature is constantly shuffling the human genome, creating a genetic cocktail of human chromosomes and trying out different changes as it does so.”


TOPICS: Culture/Society; Miscellaneous; News/Current Events; Technical
KEYWORDS: blueeyes; eugenics; evolution; genetic; genetics; godsgravesglyphs; helixmakemineadouble; incest; mutation
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To: Sherman Logan

I think you meant a one if four chance.


81 posted on 01/30/2008 2:46:34 PM PST by Blood of Tyrants (G-d is not a Republican. But Satan is definitely a Democrat.)
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To: decimon
Now, blue hair, that's something!


82 posted on 01/30/2008 2:46:52 PM PST by Revolting cat! (We all need someone we can bleed on...)
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To: vortigern
Did Goebbels say anything about Hitler’s bushy little mustache?
83 posted on 01/30/2008 2:47:31 PM PST by Sawdring
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To: decimon

Maybe it’s when God breathed life into man. Just musing in the most politically incorrect way I can think of.


84 posted on 01/30/2008 2:47:40 PM PST by isrul
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To: fishtank

So whom did Noah’s son’s children marry? Each other?

I’ve always wondered about that.


85 posted on 01/30/2008 2:48:18 PM PST by FixedandDilated
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To: decimon
The mutation of brown eyes to blue represents neither a positive nor a negative mutation.

Blue eyes are acknowledged to be more sensitive to light, and that's an advantage in areas with less light more of the year, such as northern Europe—where there happen to live most of the blue-eyed people on earth. So, how can it be neither positive nor negative? Perhaps a European advantage for surviving in Europe is just too politically incorrect a thought to harbor in one's mind.

The whole thing sounds like B.S. anyway.

86 posted on 01/30/2008 2:48:26 PM PST by SamuraiScot
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To: avacado

Similar to me...

Mom - green
Dad - brown
Sis - brown
Me - blue
Bro - green
Sis - brown
bro - brown


87 posted on 01/30/2008 2:48:53 PM PST by Scarpetta (e pluribus victim)
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To: GQuagmire

Maybe possible, but I never saw it.

We always sent them for a paternity test, and the news was always bad.

In fact, there was a form to fill out with check marks to see who got the free paternity test — “admitted infidelity,” and “blue/blue/brown” were two of the boxes.


88 posted on 01/30/2008 2:49:27 PM PST by TheThirdRuffian (Don't blame me; I will write in Thompson.)
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To: Revolting cat!
Pink hair, too.


89 posted on 01/30/2008 2:49:56 PM PST by CholeraJoe ("A dead whale or a stove boat!")
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To: LexBaird

I set myself up for this.......


90 posted on 01/30/2008 2:50:15 PM PST by GQuagmire (Giggety,Giggety,Giggety)
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To: decimon
The most beautiful woman in the world has blue eyes (or maybe not.)


91 posted on 01/30/2008 2:50:21 PM PST by Revolting cat! (We all need someone we can bleed on...)
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To: rfp1234
Look at the difference in the dilation of his eyes. Is he concussed???
92 posted on 01/30/2008 2:51:03 PM PST by Constitutions Grandchild
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To: GQuagmire
I’ll play along. I have blue eyes. My parents have brown eyes. Is my father my father? /lol

Actually that depends. If you're paternal grandfather or grandmother had blue eyes, probably. If not, the odds just dropped considerably.

93 posted on 01/30/2008 2:51:56 PM PST by Centurion2000
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To: Revolting cat!

94 posted on 01/30/2008 2:53:21 PM PST by blam (Secure the border and enforce the law)
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To: blam

Didn’t you used to have an animated map showing before and after?


95 posted on 01/30/2008 2:53:34 PM PST by CholeraJoe ("A dead whale or a stove boat!")
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To: TheThirdRuffian
It is impossible, barring mutation, for two blue-eyed parents to have a non-blue eyed baby. (You can sometimes get green, but I can’t remember how.)

LOL! Plus his wife lived in Japan while he was out at sea. And, yes, his son did look quite a bit Japanese. I guess this is what drove him to become a Jehovah's Witness.

96 posted on 01/30/2008 2:53:52 PM PST by PJ-Comix (Join the DUmmie FUnnies PING List for the FUNNIEST Blog on the Web)
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To: PJ-Comix

There is an article posted along here that contradicts what I said, but I sure as heck never saw it.


97 posted on 01/30/2008 2:54:42 PM PST by TheThirdRuffian (Don't blame me; I will write in Thompson.)
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To: Centurion2000

paternal grandmother


98 posted on 01/30/2008 2:56:07 PM PST by GQuagmire (Giggety,Giggety,Giggety)
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To: decimon

99 posted on 01/30/2008 2:57:09 PM PST by BaBaStooey (I heart Emma Caulfield.)
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To: blam
The Southern grouping included individuals from Greece, Italy, Portugal and Spain, as well as Ashkenazi and Sephardic Jews. The Northern group included people with English, Irish, German, Swedish and Ukranian ancestry. These groups correspond to those historically divided by the Pyrenees and Alps mountain ranges.

The Goths & later, Normans (Vikings) really got around.

100 posted on 01/30/2008 2:58:25 PM PST by GoLightly
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