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Jumping Ship From the Rats
The American Spectator ^ | 3/19/2008 | Gilbert Ross, M.D.

Posted on 03/25/2008 10:55:02 AM PDT by neverdem

We won! That is, the forces of science-based public health policy seem to have won -- if not the war, at least a major battle. At long last, federal risk assessors and regulators have come around to the view that administering chemicals to rodents in super-high doses does not reliably predict human risk -- of cancer, or anything else -- and that a better method needs to be employed, if we are to avoid more unnecessary bans, anti-chemical media hysteria, and activist crusades.

High dose animal tests on one rodent species don't reliably predict cancer risk in another rodent type, much less in humans. The same tests for "carcinogens" that are used to condemn synthetic chemicals also give false positive findings for a whole spectrum of natural substances that we safely eat, breathe, and drink every day.

The sort-of good news is that the National Institutes of Health (NIH) and the Environmental Protection Agency (EPA) just announced a new collaboration: the development of a "new paradigm" for testing potentially toxic chemicals. Drawing upon the unique testing methodologies to be found in their various sub-agencies, they plan to shift from testing chemicals on whole animals to testing the chemicals on cells and "isolated molecular targets," using high-speed, automated screening robots.

It sounds a bit science-fictiony -- a brave new world, perhaps, of chemical toxicity testing. Bypassing the high dose, long-term animal experimentation for test "subjects" -- cells -- in Petri dishes will undoubtedly save the government testers a lot of money (and also spare the lives of many rats and mice). But the real question is, will it bring some sense to the testing process for evaluating suspected chemical toxins?

ONE GOOD THING can be deduced from this new collegiality...

(Excerpt) Read more at spectator.org ...


TOPICS: Culture/Society; Editorial; Government; Technical
KEYWORDS: carcinogens; health; medicine; toxicity

1 posted on 03/25/2008 10:55:04 AM PDT by neverdem
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To: neverdem

aspartame (nutrasweet) certainly needs to be given another look. or a serious look it never got in the first place.


2 posted on 03/25/2008 11:00:29 AM PDT by kingattax (99 % of liberals give the rest a bad name)
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To: neverdem

Darn. I thought this was about somebody leaving the dem party. Instead, it’s about real rats.


3 posted on 03/25/2008 11:24:59 AM PDT by hsalaw
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To: kingattax

Yes it does, especially in light of the rate of increase of autism.


4 posted on 03/25/2008 11:29:48 AM PDT by Content Provider
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To: kingattax

Oh, I mis-spoke, I thought this was about fighting Rats

5 posted on 03/25/2008 11:31:02 AM PDT by BigLittle ( .)
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To: El Gato; Ernest_at_the_Beach; Robert A. Cook, PE; lepton; LadyDoc; jb6; tiamat; PGalt; Dianna; ...
Link to Global Warming in Frogs’ Disappearance Is Challenged

Third source of oceanic iron is found

No Bad Drugs - The arbitrary distinctions at the root of prohibition

FReepmail me if you want on or off my health and science ping list.

6 posted on 03/25/2008 6:12:42 PM PDT by neverdem
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To: hsalaw; neverdem
Me too. I thought this was about the Senator Clinton / Senator Obama debacle, and then I saw your name attached, neverdem.

Thanks!

Cheers!

7 posted on 03/25/2008 6:31:27 PM PDT by grey_whiskers (The opinions are solely those of the author and are subject to change without notice.)
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To: neverdem
The good:

The Brain is one step closer to "Taking Over the World, Pinky!"

The bad:

White mice STILL cause cancer.

My prediction:

It will not pick up on a lot of physiological effects (changes in an entire organ system which then impinge on *another* system to produce side effects.

Cheers!

8 posted on 03/25/2008 6:33:21 PM PDT by grey_whiskers (The opinions are solely those of the author and are subject to change without notice.)
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To: kingattax

Hello, aspartame is deadly, and you don’t need rats to prove it.


9 posted on 03/25/2008 9:10:33 PM PDT by Rennes Templar ( Never underestimate the difficulty of changing false beliefs by facts.)
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To: AdmSmith; Berosus; Convert from ECUSA; dervish; Ernest_at_the_Beach; Fred Nerks; george76; ...
At long last, federal risk assessors and regulators have come around to the view that administering chemicals to rodents in super-high doses does not reliably predict human risk -- of cancer, or anything else -- and that a better method needs to be employed, if we are to avoid more unnecessary bans, anti-chemical media hysteria, and activist crusades.
Of course, there were also activist crusades against using animals to test for anything, part of the incoherent luddism of the left. Thanks neverdem.
10 posted on 03/25/2008 9:48:10 PM PDT by SunkenCiv (https://secure.freerepublic.com/donate/______________________Profile updated Saturday, March 1, 2008)
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