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Researchers Look to Daily Pill to Avert H.I.V.
NY Times ^ | August 4, 2008 | LAWRENCE K. ALTMAN

Posted on 08/04/2008 1:09:57 AM PDT by neverdem

MEXICO CITY — Can a pill a day help prevent infection from H.I.V., the virus that causes AIDS?

No one knows. But researchers in a number of countries are conducting trials and planning others to test the unproven strategy that a daily pill, or a combination of drugs, can prevent H.I.V.

By mid-2009, more people will be enrolled in such trials than in all of those for H.I.V. vaccines and microbicides, the AIDS Vaccine Advocacy Coalition said in a report issued here on Sunday at the start of the 17th International AIDS Conference.

Initial findings of the safety and effectiveness might come early next year, although researchers...

--snip--

The United States Agency for International Development, the C.D.C. and the National Institutes of Health are paying in part for all of the trials. The Bill & Melinda Gates Foundation is paying for part of two. The organizations have undertaken the trials because of the success in giving antiretroviral drugs to pregnant women to prevent H.I.V. infection in their infants and drugs to prevent malaria.

--snip--

Initial PrEP studies are testing tenofovir, either alone or combined with another drug, emtricitabine.

Infected people taking these licensed drugs have shown limited side effects like nausea, vomiting, diarrhea and intestinal gas. But the safety of the drugs must be established among noninfected people as well as among participants who become infected in the study.

Trial participants include gay and bisexual men, heterosexual men and women, couples in which one partner is H.I.V. infected, and sex workers.

Up to 15,000 people are expected to be participating in trials by mid-2009. Sites of the trials include Botswana, Brazil, Ecuador, Kenya, Malawi, Peru, South Africa, Tanzania, Thailand, Uganda and the United States.

Male circumcision has proved effective in a significant percentage of H.I.V.-negative people in trials in Africa...

(Excerpt) Read more at nytimes.com ...


TOPICS: Business/Economy; Culture/Society; Government
KEYWORDS: aids; hiv; hivaids; prep
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First, do no harm! IMHO, this is nuts!
1 posted on 08/04/2008 1:09:57 AM PDT by neverdem
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To: neverdem

Oh, but it’s only antiretrovirals—balm of Gilead. Let them have it. They’re certainly not going to stop shooting up drugs and porking each other in the behind.


2 posted on 08/04/2008 1:47:12 AM PDT by Mr Ramsbotham (Barack Obama--the first black Jimmy Carter.)
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To: neverdem; All

Pardon the bluntness, but
don’t buttf*ck
don’t share dirty needles ( aggh! )
don’t have sex with those who do
and you won’t get AIDS
( or GRID- remember that one? )


3 posted on 08/04/2008 2:01:20 AM PDT by backhoe (Just an old keyboard cowboy, ridin' the Trakball in to the Sunset...)
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To: backhoe; GodGunsGuts

It’s rather paradoxical, isn’t it? They’ve got a disease that supposedly wreaks havoc on the immune system, so they fight it by taking drugs that wreak havoc on the immune system.


4 posted on 08/04/2008 2:17:47 AM PDT by Mr Ramsbotham (Barack Obama--the first black Jimmy Carter.)
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To: Mr Ramsbotham
It’s rather paradoxical, isn’t it? They’ve got a disease that supposedly wreaks havoc on the immune system, so they fight it by taking drugs that wreak havoc on the immune system.

There really are times ( like this ) when I feel like I've jumped aboard The Crazy Train, and would like to jump off.

Like that gawd-awful old joke:

A man goes to his Doctor, complaining about a pain in his arm...

He sticks it out at a weird angle, and makes it do things it was never meant to do...

"Doc, it hurts when I do this!"

"Well, quit doing that, you damn fool!"

5 posted on 08/04/2008 2:27:43 AM PDT by backhoe (Just an old keyboard cowboy, ridin' the Trakball in to the Sunset...)
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To: neverdem
Side effects are loose bowels, unexplainable eye movements, spontaneous inflammation of the hair, and sudden death.

Be sure to consult your doctor local hack for the big pharma industry.
6 posted on 08/04/2008 2:36:00 AM PDT by djf (Get ready! Buy Cheez Wiz! It goes with anything!)
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To: djf
Side effects are loose bowels, unexplainable eye movements, spontaneous inflammation of the hair, and sudden death

Sounds like liberals have 3 out of 4 side effects, guess it's just a matter of waiting for #4.
7 posted on 08/04/2008 3:21:18 AM PDT by mkjessup (Jimmy Carter is the Skidmark in the panties of American history.)
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To: neverdem

“Researchers Look to Daily Pill to Avert H.I.V.”

Saltpeter?


8 posted on 08/04/2008 3:32:39 AM PDT by PLMerite ("Unarmed, one can only flee from Evil. But Evil isn't overcome by fleeing from it." Jeff Cooper)
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To: neverdem
I have a much cheaper idea with fewer side effect. It's something called monogamy.
9 posted on 08/04/2008 4:10:37 AM PDT by Gamecock (The question is not, Am I good enough to be a Christian? rather Am I good enough not to be?)
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To: neverdem
"Here, take this pill and bend over for the for the dope shootin gay junkie!"

Uhh, Errr, no thanks, think i'll pass on that one!!!!

10 posted on 08/04/2008 5:14:26 AM PDT by Cheapskate (Still backing Hunter"I refuse to be fitted with collar and chain, and given a pat on the back")
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To: Mr Ramsbotham; Stentor; Marty; Fractal Trader; metmom; John Valentine; editor-surveyor; ...

Thanks for the ping, Ramsbotham. Did you read the PDF link to the AIDS Vaccine Advocacy Coalition in the NY Times article? Here it is in case you missed it. These people are clearly insane!

http://www.avac.org/prep08.pdf


11 posted on 08/04/2008 9:38:52 AM PDT by GodGunsGuts
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To: All

If you would like to be added to the RETHINKING AIDS PING LIST drop me a FReepmail.

AIDS is the biggest public health scam in medical history. Like global warming, AIDS is being used to push a powerful leftist political agenda. For over two decades the Public Health Establishment has used your tax dollars and the full power of the federal government to wage a massive propaganda (and intimidation) campaign designed to (A) dupe the American public into believing that HIV is the cause of AIDS (B) scare the public into thinking "we are all at risk" (C) coverup the extreme toxicity of AIDS chemotherapy drugs (which are not just used on "fast-track" gays and junkies, but also given to pregnant mothers, infants, and children) (D) use this fear to push a leftist social agenda that includes socialized medicine, and the promotion of homosexuality and explicit sex "education" to tender-aged school children (E) use their "public health mandate" to bypass the authority of parents and local school boards who object to their social engineering schemes (F) create a massive federal bureaucracy encouraging the use of addictive drugs, to include prescription heroine (G) use threats and intimidation to silence dissenting scientists and to keep the press from covering the debate (H) and finally, to use AIDS as a model to push similar social agendas with respect to future epidemics.

Every single point above can be documented on my profile page.


12 posted on 08/04/2008 9:39:55 AM PDT by GodGunsGuts
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To: neverdem

==First, do no harm! IMHO, this is nuts!

Finally reached your limit, eh Neverdem?


13 posted on 08/04/2008 9:42:38 AM PDT by GodGunsGuts
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To: allmendream

Seen this one?


14 posted on 08/04/2008 9:43:21 AM PDT by GodGunsGuts
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To: GodGunsGuts
Finally reached your limit, eh Neverdem?

No. Risking adverse drug reactions for an otherwise avoidable disease is just stupid.

I wouldn’t hang my hat on some studies from Africa like Duesberg does. There are other well done studies from Africa that show circumcision cuts the rate of HIV/AIDS by half or more. Before HIV/AIDS, most IDU/IVDA died from drug overdoses, not rare opportunistic infections. You still haven’t explained the dramatic decreases in vertical transmission, mother to child, in HIV positive mothers with only perinatal antiretroviral drug treatment.

15 posted on 08/04/2008 10:50:37 AM PDT by neverdem (I'm praying for a Divine Intervention.)
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To: GodGunsGuts
Did you read the PDF link to the AIDS Vaccine Advocacy Coalition in the NY Times article? Here it is in case you missed it. These people are clearly insane!

Hmmm. I think I'm going to talk to my oncologist about starting a program of aggressive chemotherapy and radiation treatments--just in case I get cancer some time down the line!

16 posted on 08/04/2008 2:18:05 PM PDT by Mr Ramsbotham (Barack Obama--the first black Jimmy Carter.)
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To: Mr Ramsbotham

LOL!


17 posted on 08/04/2008 2:18:58 PM PDT by GodGunsGuts
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To: neverdem; GodGunsGuts
You still haven’t explained the dramatic decreases in vertical transmission, mother to child, in HIV positive mothers with only perinatal antiretroviral drug treatment.

Vertical transmission of what? HIV or AIDS? I'd expect the former, but it would be interesting to see the stats on the latter.

18 posted on 08/04/2008 2:20:16 PM PDT by Mr Ramsbotham (Barack Obama--the first black Jimmy Carter.)
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To: Mr Ramsbotham

PS I hope you don’t mind if I borrow that from time to time...just told my wife, now she’s LOLing too.


19 posted on 08/04/2008 2:21:35 PM PDT by GodGunsGuts
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To: GodGunsGuts
PS I hope you don’t mind if I borrow that from time to time...

Not at all!

20 posted on 08/04/2008 4:33:14 PM PDT by Mr Ramsbotham (Barack Obama--the first black Jimmy Carter.)
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