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Aussie cancer breakthough holds promise for leukemia, arthritis
Courier Mail ^ | August 12, 2008 | Tamara McLean

Posted on 08/12/2008 10:44:30 AM PDT by Schnucki

NEW treatments for leukemia and asthma are in development after scientists discovered a way to stop the production of malfunctioning blood cells. Researchers at the St Vincent's Institute in Melbourne and Hanson Institute in Adelaide have unravelled the structure of a protein in the blood control system that is key to some blood and inflammatory disorders.

Pharmaceutical company CSL will use the breakthrough to develop new treatments which stop the protein from being activated, hindering the spread of cancer.

Professor Michael Parker, of the St Vincent's Institute, said his team established the structure of a receptor that controls the actions of a blood-forming regulator called GM-CSF.

"This regulator has been of interest to researchers and clinicians for many years now because its controller or receptor, found on the surface of blood cells, is critical in regulating their many functions," Professor Parker said.

In leukemia, an excessive number of malfunctioning white blood cells are produced because some of the signals coming from the receptor are abnormal.

"Because our discovery shows precisely what the receptor looks like and also how it works, we can now begin to design new drugs to rein in the deadly abnormal blood cells," Professor Parker said.

(Excerpt) Read more at news.com.au ...


TOPICS: Culture/Society
KEYWORDS: australian; breakthrough; cancer; health; healthcare

1 posted on 08/12/2008 10:44:30 AM PDT by Schnucki
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To: neverdem

that pingie thingie!


2 posted on 08/12/2008 11:10:48 AM PDT by fightinJAG (Rush was right when he said: "You NEVER win by losing.")
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To: texas booster

Folding ping


3 posted on 08/12/2008 11:19:08 AM PDT by Straight Vermonter (Posting from deep behind the Maple Curtain)
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To: Schnucki

Good news. . .hope the ‘rest of the story’ is a timely one.


4 posted on 08/12/2008 11:20:15 AM PDT by cricket (Damn Political Correctness; before it damns us all. . .)
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To: Schnucki
I have Rheumatoid Arthritis, and this certainly good news (or a step in the direction of good news) for me. I want to live long enough to be cure of RA by autologous blood stem cell therapy.

Can I have an 'Amen'?

5 posted on 08/12/2008 11:48:35 AM PDT by Mrs. Don-o (Thanks.)
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To: fightinJAG

Thanks for the ping.


6 posted on 08/12/2008 12:17:01 PM PDT by neverdem (I'm praying for a Divine Intervention.)
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To: Schnucki

So happy for this news.

I wish also there was a breakthrough for melanoma treatment.


7 posted on 08/12/2008 12:38:47 PM PDT by diamond6 (Everyone who is for abortion has been born. Ronald Reagan)
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To: Mrs. Don-o

Amen!


8 posted on 08/12/2008 10:45:33 PM PDT by TigersEye (Berlin '36 ... Olympics for murdering regimes. ... Beijing '08)
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