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How manuka honey helps fight infection
biologynews.net ^ | September 7, 2009 | NA

Posted on 09/15/2009 8:07:49 PM PDT by neverdem

Manuka honey may kill bacteria by destroying key bacterial proteins. Dr Rowena Jenkins and colleagues from the University of Wales Institute - Cardiff investigated the mechanisms of manuka honey action and found that its anti-bacterial properties were not due solely to the sugars present in the honey. The work was presented this week (7-10 September), at the Society for General Microbiology's meeting at Heriot-Watt University, Edinburgh.

Meticillin resistant Staphylococcus aureus (MRSA) was grown in the laboratory and treated with and without manuka honey for four hours. The experiment was repeated with sugar syrup to determine if the effects seen were due to sugar content in honey alone. The bacterial cells were then broken and the proteins isolated and separated on a system that displayed each protein as an individual spot. Many fewer proteins were seen from the manuka honey-treated MRSA cells and one particular protein, FabI, seemed to be completely missing. FabI is a protein that is needed for fatty acid biosynthesis. This essential process supplies the bacteria with precursors for important cellular components such as lipopolysaccarides and its cell wall. The absence of these proteins in honey-treated cells could help explain the mode of action of manuka honey in killing MRSA.

"Manuka and other honeys have been known to have wound healing and anti-bacterial properties for some time," said Dr Jenkins, "But the way in which they act is still not known. If we can discover exactly how manuka honey inhibits MRSA it could be used more frequently as a first-line treatment for infections with bacteria that are resistant to many currently available antibiotics".


TOPICS: Culture/Society; News/Current Events; Testing
KEYWORDS: health; honey; infection; manukahoney; medicine; microbiology; mrsa

1 posted on 09/15/2009 8:07:50 PM PDT by neverdem
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To: decimon

ping


2 posted on 09/15/2009 8:09:13 PM PDT by neverdem (Xin loi minh oi)
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To: neverdem

Ping


3 posted on 09/15/2009 8:16:37 PM PDT by Truth is a Weapon (Truth, it hurts soooo good!)
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To: neverdem
File this under the 'FWIW' category...

For years I had a persistent condition on the skin of my shin that no doctor could successfully treat. Eventually the symptoms worsened, including the formation of blisters (which, alarmingly, is a symptom of gangrene!). Some mornings I would wake up to find the area warm to the touch, and a very disturbing indentation in the flesh of my shin.

In desperation I ordered a jar of manuka honey from a vendor in New Zealand (having heard about it somewhere), and applied it for a couple of days over the skin.

Within a few days the symptoms abated, and today I have only a slight discoloration of the skin as a reminder of that scary multi-year episode.

Hopefully my experience will be of benefit to someone else.

4 posted on 09/15/2009 8:22:32 PM PDT by The Duke ("Are you now or have you ever been a member of the Democrat Party?")
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To: neverdem; metmom; TigersEye

I used raw honey on a bug bite on my foot that went into MRSA last summer. It worked better then then the horrible drugs.


5 posted on 09/15/2009 8:24:17 PM PDT by pandoraou812 (elected officials should be required to pass drug, alcohol & dementia testing)
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To: pandoraou812

Another FYI, honey is the one kind of sugar/glucose that will not cause your insulin levels to spike.


6 posted on 09/15/2009 8:32:16 PM PDT by Secret Agent Man (I'd like to tell you, but then I'd have to kill you.)
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To: Secret Agent Man

Good,I just ate two tablespoons hoping it would calm my upset stomach.


7 posted on 09/15/2009 8:37:50 PM PDT by madison10
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To: neverdem

all kinds of honey have anti bacterial properties. it also helps wounds stop bleeding faster,dries to form a natural bandage, and has been shown in scientific studies to speed healing of cuts, scrapes, even surgical incisions.


8 posted on 09/15/2009 8:37:55 PM PDT by madamemayhem (defeat isn't getting knocked down, it's not getting back up)
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To: Secret Agent Man

Thanks, I wasn’t aware of that. I don’t have to worry about insulin levels yet.


9 posted on 09/15/2009 8:38:12 PM PDT by pandoraou812 (elected officials should be required to pass drug, alcohol & dementia testing)
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To: Mother Abigail; EBH; vetvetdoug; Smokin' Joe; Global2010; Battle Axe; null and void; ...
micro ping

Piece from childhood virus may save soldiers' lives

10 posted on 09/15/2009 8:40:01 PM PDT by neverdem (Xin loi minh oi)
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To: neverdem

Yes, it works. It also helps clear up acid reflux. I keep a jar on hand at all times.


11 posted on 09/15/2009 8:42:44 PM PDT by WVNan ( (Attack him where he is unprepared, appear where you are not expected.: Sun Tzu))
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To: madamemayhem

Honey was used as a wound antiseptic as recently as WWI.


12 posted on 09/15/2009 8:43:32 PM PDT by Lurker (The avalanche has begun. The pebbles no longer have a vote.)
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To: madamemayhem

Honey was used by the ancient Egyptians to prevent infections. It was also used by them as a preservative. Food items stored in honey remained edible long after it would have otherwise rotted. The Jewish notion of going to a “land of milk and honey” indicated a land of both good nourishment and good health.


13 posted on 09/15/2009 8:55:25 PM PDT by Kirkwood
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To: The Duke

How did you do it? Clean it daily, then apply the honey under a dressing?


14 posted on 09/15/2009 9:03:31 PM PDT by neverdem (Xin loi minh oi)
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To: neverdem

macro thanks - I am always too busy reading to thank you.


15 posted on 09/15/2009 9:12:49 PM PDT by bitt (“You can’t make a weak man strong by making a strong man weak.” (Abraham Lincoln))
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To: neverdem

Needs to be “live” Manuka Honey...I use it on my sons acne.


16 posted on 09/15/2009 9:16:41 PM PDT by hope
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To: WVNan; Secret Agent Man
Acid Reflux and insulin

Thanks for that info. I have Manuka but didn't know of those benefits.
17 posted on 09/15/2009 9:18:01 PM PDT by presently no screen name
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To: madamemayhem

I just put it on a canker sore and it burns like fire!


18 posted on 09/15/2009 9:21:23 PM PDT by tiki (True Christians will not deliberately slander or misrepresent others or their beliefs)
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To: Lurker
Honey was used as a wound antiseptic as recently as WWI.

I think they're using it now. That was the story maybe a year ago. Some company making gauze pads with honey and IIRC, manuka honey.

19 posted on 09/15/2009 9:22:50 PM PDT by decimon
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To: neverdem

Thanks. I wondered what happened to this stuff.


20 posted on 09/15/2009 9:23:47 PM PDT by decimon
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I thought all honeys had this property?


21 posted on 09/15/2009 9:29:47 PM PDT by D-fendr (Deus non alligatur sacramentis sed nos alligamur.)
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To: Secret Agent Man

Why is my mind resisting this?


22 posted on 09/15/2009 11:22:58 PM PDT by definitelynotaliberal (So how about, in honor of the American soldier, ya quit making things up? - Gov. Palin)
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To: definitelynotaliberal

I have no idea why you are resisting this. All that is written about honey here is provable. I have used honey for mulitple reasons for many years—including applying it to an infected area. It works.

It also can make a great cough syrp—that really works. Just slice an onion, put it in a shallow bowl and drizzle a generous amount of honey over it. Wait a couple of hours. A liquid will form in the bottom of the bowl. Take several tablspoons of that liquid several times a day. Your bronchitis will get better very soon.


23 posted on 09/15/2009 11:38:41 PM PDT by Running On Empty ((The three sorriest words:"It's too late"))
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To: Running On Empty
My father (born in 1901) gave me the best receipt for cough syrup and phlegm that his family used. It is equal parts of honey, lemon juice and whiskey... for instances 2 tablespoons of each. Put in glass jar with lid and shake to mix before taking a teaspoon.

I remember one patient when I worked on the pediatric ward that the doctor had tried everything on..poor little tyke was in oxygen tent...He wrote an order to pharmacy for that exact medication, the baby was given 1/4 tsp. every 3 hours...it worked on the phlegm that was chocking him.

24 posted on 09/16/2009 12:01:31 AM PDT by goat granny
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To: neverdem
These guys need to give their grant money back.

The ancient Egyptians discovered that un-pasteurized honey was a strong disinfectant and used it onall manner of wounds.

25 posted on 09/16/2009 3:43:55 AM PDT by Jimmy Valentine (DemocRATS - when they speak, they lie; when they are silent, they are stealing the American Dream)
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To: goat granny

I think I might like your recipe better than mine :-).

A little bit of honey, a little bit of zesty lemon and a little bit of Jameson whiskey—the sweet, the zesty and the Irish whiskey. Can’t beat that.


26 posted on 09/16/2009 4:14:16 AM PDT by Running On Empty ((The three sorriest words:"It's too late"))
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To: neverdem

Honey has long been used in medicinal ways. I’m glad to see they are actively pursuing it’s uses and varieties. And it’s delicious, too! Mmmm, honey!


27 posted on 09/16/2009 7:53:07 AM PDT by fortunecookie (Please pray for Anna, age 7, who waits for a new kidney.)
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To: Running On Empty

I believe that. I have no doubts that it is an anti-microbial. My resistance is to the position that it doesn’t cause the same spike in insulin as sugar. That I’d like to learn more about.


28 posted on 09/16/2009 9:04:28 AM PDT by definitelynotaliberal (So how about, in honor of the American soldier, ya quit making things up? - Gov. Palin)
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To: neverdem
How did you do it? Clean it daily, then apply the honey under a dressing?

Yep, that was pretty much it. I'm still amazed at the results. Before the honey it was truly a nightmare what was happening - that was maybe 8 years ago, and no problems since, with full recovery.

29 posted on 09/16/2009 12:49:03 PM PDT by The Duke ("Are you now or have you ever been a member of the Democrat Party?")
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To: The Duke

Thanks for the feedback!


30 posted on 09/16/2009 12:59:58 PM PDT by neverdem (Xin loi minh oi)
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