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Health warning over statin taken by millions (Simvastatin)
Daily Telegraph ^ | 03/20/10 | Rebecca Smith

Posted on 03/20/2010 4:54:22 PM PDT by TennesseeGirl

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To: CaspersGh0sts
This is old news, folks. They’re talking about rhabdomyolysis, which is where your muscles can begin to breakdown, ache, and cause renal failure. It’s pretty rare.

Yep. The various heart publications indicate that if you're going to have problems, they normally will happen in the first few months.

Since 1995 I have taken high doses of Lipitor followed by simvastatin 80mg. I had 6 coronary bypasses in 1981 and now, 29 years later, the bypasses are still open. Liver and kidney functions have been normal, checked regularly. Haven't had muscle problems in that time so I'm not likely to be scared off quickly.

41 posted on 03/20/2010 5:59:06 PM PDT by Ole Okie
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To: vaudine

Nose bleeds? Now that’s something different.

If you can’t, you can’t. I’m afraid not to take them
now after not taking them before my operation.

I don’t want more by-passes or what I fear the most...stroke.


42 posted on 03/20/2010 5:59:46 PM PDT by TribalPrincess2U (demonicRATS... taxes, pain and slow death. Is this what you want?)
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To: Carley

Sounds like you were taking lisinopril. Maybe you see try a ARBS (Angiotensin II receptor blockers ).

T. Package RN


43 posted on 03/20/2010 6:02:12 PM PDT by Total Package (TOLEDO, OHIO THE MRSA INFECTION IN THE STATE and the death of freedom)
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To: conservaDave
80mg is a very high dose. I was on 40 at a high and now 20. Numbers good.

I agree. I'm on 20 mg. Simvastatin with 10 mg. Zetia and have great numbers with no ill effects in over a year.

44 posted on 03/20/2010 6:04:34 PM PDT by Bernard Marx (I donÂ’t trust the reasoning of anyone who writes then when they mean than.)
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To: Total Package

Yup, the notorious lisinopril. Oh that kennel cough was something else.


45 posted on 03/20/2010 6:05:01 PM PDT by Carley (Are you better off now than one year ago? HELL NO!!!!!)
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To: TribalPrincess2U
Red Yeast Rice has the same properties as the statin drugs but without the adverse reactions. Drug companies have been pushing to get it off the market...does that tell you something?

Read up on it...it may be something of interest.

46 posted on 03/20/2010 6:08:19 PM PDT by A_Tradition_Continues (formerly known as Politicalwit ...05/28/98 Class of '98...PROCESS MATTERS)
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To: conservaDave

80mg is a very high dose. I was on 40 at a high and now 20. Numbers good.

***

I’m on 40 mg - have noticed shaking in left hand recently. Numbers have been stable for 2+ yeasr now, about 155-165 total cholesterol.

Was wondering if I could decrease ...


47 posted on 03/20/2010 6:12:05 PM PDT by Lmo56
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To: Vaquero

I give up, what’s peripheral, etc
?


48 posted on 03/20/2010 6:15:38 PM PDT by brivette (paper)
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To: truthguy
I've been off statins (poison) for over 3 years. Once I found out that this whole "cholesterol Problem" was/is a huge sham, and learned about the side-effects (that I was experiencing for years but didn't know any better), I told my doc that I wasn't going to take any of them anymore. He didn't argue much. Seriously, anyone that has been taking them and has any concerns, do a little research.

In short:

- "target" levels were established to ensure enough of the population would fall "at risk" (even been adjusted lower to get more users over time)

- the statins cross the blood-brain barrier and kill off cholesterol in the brain that is not easily replenishable (BTW, the body, esp. the brain NEEDs cholesterol to function and grow!)

- I went and had one of the cardiac scoring high-tech MRIs that you have to pay for out of pocket (most ins. don't cover) and found out that I have way less than 10% scaling, which based on my age, is quite good (it is actually the scaling or calcification in the arteries that is a cause of heart disease, not a high cholesterol level!)

- all of the studies that they have done over the years can only establish a very weak (almost non-existent) relationship between the use of statins and lower instances of heart disease

Obviously everyone should do their own research (i.e., not rely on an AMA member) and make their own decision. I have felt so much better since I stopped and have had all of those nasty side effects disappear over time.

49 posted on 03/20/2010 6:16:54 PM PDT by zzeeman (Fighting to not be the amongst the last generation to enjoy freedom & liberty!)
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To: TribalPrincess2U
My husband had 4 bypasses a year ago. He couldn't take most of the medicines they put him on. They took him off amioderone)spelling?), and a couple others He takes blood thinner for atrial flutter and the smallest dose possible of a beta blocker (coreg). He is 82, and I am glad he had the operation before the possibiity of Obamacare. He is doing well.

Iunderstand your fear. Most people feel the same as you--afraid not to because the dr. prescribes; just read everything you can about statins. If you haven't subscribed to Newsmax, do so and you will get bulletins on health news. Between the fact that the normal high for cholesterol as well as LDL, triglicerides, etc. were lowered drastically a couple decades ago, and the huge side effects listed for statins, plus the 2 or 3 huge research programs that have been terminated early because the statin group were having many more strokes and heart attacks tha the placebo group--I am much more afraid to take them than not.

vaudine

50 posted on 03/20/2010 6:18:38 PM PDT by vaudine
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To: TennesseeGirl

Wow, this has been known since around 1990. I used to sell a competing statin and it was well known that simvastatin and lovastatin had a propensity to cause rhabdo at high doses. But, 80mg is a very high dose of simvastatin. I’ve been prescribed 40mg of pravastatin, and I do think I have had some issues from it as well, if I take it every day.

The nice thing about Crestor is that it is apparently pretty effective even at doses as low as 5mg. I think if I switch, I’d like to try Crestor.

Also, I am concerned about how low they are trying to drive cholesterol levels. Cholesterol is necessary for formation of the connective tissue in the brain. I wonder about the wisdom of driving cholesterol down to very low levels in the elderly, who are at higher risk of hemorrhagic stroke. If you have lived past 70, you need to ask your doctor about your particular risk/benefit equation with respect to statin therapy.


51 posted on 03/20/2010 6:20:00 PM PDT by mtrott
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To: truthguy

Just happened to me, doctor just about beat me on the head to start with Zetia.

I used it one month, lowered my LDL 13% instead of the 25 to 30% he said was normal, so I’ve quit it.


52 posted on 03/20/2010 6:23:05 PM PDT by Balding_Eagle (If America falls, darkness will cover the face of the earth for a thousand years.)
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To: A_Tradition_Continues
Red Yeast Rice has the same properties as the statin drugs but without the adverse reactions.

Yes, I take RYR, Triple Omega, Phosphatidl Choline Complex, and CoQ10 (in addition to the rest of my daily vitamins and supplements). Like others have said in the thread: good high-fiber diet, exercise, and maintaining a good attitude are very important.

Oh and BTW, every body creates a varying amount of cholesterol, some bodies create more than others, naturally, independent of diet. So any responsible doctor (even an AMA member) should speak about general guidelines, not universal rules/laws in regard to a person's cholesterol level. (Of course, I haven't met one that does!)

And some wonder why the docs are so fast to write out the prescriptions? I'm sure that you are aware of all of the "incentives" that the drug companies give them based on the volume of scripts written, that is a huge driver.

53 posted on 03/20/2010 6:28:08 PM PDT by zzeeman (Fighting to not be the amongst the last generation to enjoy freedom & liberty!)
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To: Viking2002
Get your testosterone checked.

No, I am not casting slurs on your manliness but it is very common for older men to have drops in testosterone. That can cause all sorts of nasty things to happen.

Of course it could also be that being recently married you are not getting enough sleep. :)

54 posted on 03/20/2010 6:28:46 PM PDT by Harmless Teddy Bear (I miss the competent fiscal policy and flag waving patriotism of the Carter Administration)
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To: Balding_Eagle

Zetia—why? It has never been shown to reduce cardiac events. No way Zetia will lower cholesterol 25-30% by itself.


55 posted on 03/20/2010 6:29:17 PM PDT by mtrott
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To: TennesseeGirl

Great. My Dr. just prescribed this for me.


56 posted on 03/20/2010 6:29:21 PM PDT by tang-soo (Prophecy of the Seventy Weeks - Read Daniel Chapter 9)
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To: Harmless Teddy Bear; Viking2002

Also if one took medicinal steroids within the past year, sometimes the bodily production of its own steroids can shut down.


57 posted on 03/20/2010 6:31:11 PM PDT by HiTech RedNeck (I am in America but not of America (per bible: am in the world but not of it))
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To: HiTech RedNeck

I was not aware of that. Interesting.


58 posted on 03/20/2010 6:34:50 PM PDT by Harmless Teddy Bear (I miss the competent fiscal policy and flag waving patriotism of the Carter Administration)
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To: Marty62

Same here. Had problems I had never experienced before. Doc said to stop. I’m fine now.


59 posted on 03/20/2010 6:38:00 PM PDT by BunnySlippers (I LOVE BULL MARKETS . . .)
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Comment #60 Removed by Moderator


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