[bert]

I am in the last thirty days of a drug trial for the drug Code names ASP 1941. At this point I don’t know if I am taking one of the four provided dosages or metformin or a placebo.

In about 12 weeks or so, my A1c is down slightly from 7.1 to 6.8 and morning fasting glucose is stabilizing around 135 or so. I have lost around 6% of my body weight and according to my WII, have effectively lowered my BMI from obese to over weight.

I suffered no adverse side effects normal to ASP 1941 or Metformin. My only known effect is days when I am totally wiped out. I attributed this to lower than normal glusose level but leaned that it may result from low blood pressure. The reason for lowered blood pressure was not yet determined.

Any way, it is interesting to see all this up close. My file is now at least 200 pages in a looseleaf binder.

The next 30 days will be a continuation of the monitoring but no medication.

[neverdem]

I am in the last thirty days of a drug trial for the drug Code names ASP 1941.

Ask them the mechanism of action for ASP 1941 before you're finally out the door, please?

My only known effect is days when I am totally wiped out. I attributed this to lower than normal glusose level but leaned that it may result from low blood pressure. The reason for lowered blood pressure was not yet determined.

Maybe you have metabolic syndrome, aka syndrome X, which includes high blood pressure. By losing weight and treating the type 2 diabetes a drop in blood pressure might be a physiologic response. We're you taking drugs for high blood pressure or a large prostate?

Thanks for the update.

[upchuck]

Thank you for that info. Glad you’re improving.